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Molecular Biology Core

The Molecular Biology Core in the U-M Medical School Department of Ophthalmology & Visual Sciences facilitates and expedites vision research by providing an array of services involving molecular biology technologies, statistical genetics, bioinformatics.

The Core also provides access to large equipment that would be impractical for a single lab to acquire or maintain.

For More Information

Project Priorities
Collaborative Vision Research Investigations
NEI-funded Investigations
Pilot Data Generation for Vision Grant Proposals

Our Services
  • Maintenance/oversight of Core equipment
  • Training and certification for experimentation involving Core equipment and protocols
  • Facilitating MCORES usage
  • Gene expression, statistical, analytical experiment support and analysis
  • ‘OMICS data storage (as needed)
  • Emergency and defrosting freezer storage

Contact
Sumathi Shanmugam
Research Lab Specialist Lead
Phone: 734-615-8596

Experimentation & Protocols
  • SNP and GWAS analysis
  • Gene expression data analysis
  • Quantitative PCR assay design and analysis
  • RNA-Seq sequence data processing pipeline, differential expression and bioinformatic analysis for bulk and single-cells
  • Other molecular biology protocols, depending on availability

Equipment

Note: Some pieces of equipment must be reserved for use.

  • Agilent 2200 Tape Station
  • Agilent Bioanalyzer 2100
  • BioTek Epoch plate Spectrophotometer
  • Thermo Fisher Scientific Nanodrop 1000 Spectrophotometer
  • PerkinElmer Lambda Bio20 UV/Vis Spectrophotometer
  • BioRad CFX 96
  • BioRad CFX 384
  • BioRad Opus 384
  • Azure Biosystems 600 Imaging System
  • Large capacity centrifuges
  • Beckman Avanti J-26 centrifuge
  • Beckman Coulter Opima L-90K ultracentrifuge
  • Sorvall Super T21 centrifuge
  • Benchtop centrifuges
  • Vacuum concentrators
  • Savant ISS 110 Integrated SpeedVac System
  • Ultrapure water purification systems
  • Milli-Q Reference (2)
  • Tuttnauer-Brinkman 3870E tabletop autoclave

Equipment Reservation Calendars

Note: Log into the MiCores reservation calendar site to view these calendars.

Core Director
See all Ophthalmology & Visual Sciences faculty portrait of Steven Abcouwer

Steven Abcouwer
Research Professor
Ophthalmology and Visual Sciences
Medical School