Computer screen with data
Microbiome

The microbes that live in and on us direct our immune status, susceptibility to disease, physiological development and metabolism.

DNA sequencing of the microbial community in humans and animals during disease and health allows us to examine critical changes in this community that influence our well-being. These studies are supplemented with detailed transcriptomic, proteomic and metabolomic data that reveal the underlying biochemical processes of these microbes that dictate health status.

Areas of Investigation

We work on several areas of microbiome:

  • How the gastrointestinal community (gut microbiota) influences susceptibility to enteric pathogens including Clostridium difficile and E. coli as well as the progression of inflammatory bowel diseases and colorectal cancer
  • How individual bacterial species harvest carbohydrate nutrition from the host diet in order to persist in the gut environment
  • The microbial ecology of mucosal surfaces including the gut, lungs, nasal cavity and vagina and the influence of these microbes in shaping mucosal immunity
  • The evolution of antibiotic resistance, and tracking bacterial pathogen outbreaks
Faculty researching Microbiome
BalunasMarcy22-1200x1500.png ( Marcy Balunas, PhD
Associate Professor of Microbiology and Immunology
Associate Professor of Medicinal Chemistry
College of Pharmacy
Robert Dickson Robert Pickett Dickson, MD
Associate Professor of Internal Medicine
Associate Professor of Microbiology and Immunology and Associate Fellowship Director
Pulmonary and Critical Care Medicine
headshot of Gary Huffnagle Gary B Huffnagle, PhD
Nina and Jerry D Luptak Research Professor
Research Professor
Mary H Weiser Food Allergy Center
Professor of Internal Medicine
Professor of Microbiology and Immunology
Professor of Molecular, Cellular and Developmental Biology
College of Literature, Science, and the Arts
profile-nicole-koropatkin-2023 Nicole M Koropatkin, PhD
Associate Professor of Microbiology
Immunology
labcoat Eric C Martens, PhD
Professor of Microbiology and Immunology
headshot of Pat Schloss Patrick Schloss, PhD
Program Director of Microbiology and Immunology AP&A
Frederick G Novy Collegiate Professor of Microbiome Research and Professor of Microbiology and Immunology
schmidt-tom Thomas Schmidt, PhD
Professor of Internal Medicine
Professor of Microbiology and Immunology
Professor of Ecology and Evolutionary Biology
College of Literature, Science, and the Arts
labcoat David H Sherman, PhD
Professor
labcoat Evan Snitkin, PhD
Associate Professor of Microbiology and Immunology
Associate Professor of Internal Medicine
young-vince Vincent B Young, MD, PhD
William Henry Fitzbutler Collegiate Professor of Internal Medicine
Professor of Internal Medicine
Professor of Microbiology and Immunology