women in lab examining sample jar, one woman points at the sample
Bacterial Pathogens

There are many different bacteria that cause many diseases. At the University of Michigan Medical School Department of Microbiology & Immunology, we study a wide variety of gram-positive and gram-negative pathogens. 

A common method to classify bacteria is Gram staining which distinguishes between gram-positive (the bacteria turns blue) and gram-negative bacteria (which do not retain the stain and are red or pink). The term “Gram” refers to a specimen staining method developed by Hans Christian Gram in 1884. It involves staining an organism with crystal violet or methylene blue dye and then observing the organism under a microscope.

Areas of Investigation

Some of the pathogens include:

  • Mucosal pathogens: Campylobacter jejuni, E. coli, Helicobacter pylori, Proteus mirabilis, Vibrio cholerae
  • Intracellular pathogens: Legionella pneumophila, Listeria monocytogenes)
  • Select agents: Bacillus anthracis, Brucella spp., Yersiniapestis, Mycobacteria tuberculosis).
  • Toxin secretion (cholera toxin) and antimicrobial and therapeutic agent: Actinomycetes, Cyanobacteria, Myxobacteria spp.

Other aspects of study include vaccine development and mathematical modeling of infection.

Faculty researching Bacterial Pathogens
headshot of Michael Bachman Michael A Bachman, MD, PhD
Associate Professor of Pathology
Associate Professor of Microbiology and Immunology
Medical Director, Clinical Microbiology Laboratory
Program Director, Clinical Research
Clinical Pathology Division
Suzy Dawid Suzanne Dawid, MD, PhD
Andrew B Briskin Research Professor of Pediatrics
Associate Professor of Pediatrics
Associate Professor of Microbiology and Immunology
Philip C. Hanna Philip C Hanna, PhD
Professor of Microbiology and Immunology
MS Program Director, Microbiology and Immunology
KirschnerDenise22-large-853x1280 copy.jpeg Denise E Kirschner, PhD
Program Director, Microbiology and Immunology Mentoring Program
Professor of Microbiology and Immunology
labcoat Eric C Martens, PhD
Professor of Microbiology and Immunology
headshot of Harry Mobley Harry L Mobley, PhD
Frederick G Novy Distinguished University Professor of Microbiology and Immunology
Frederick Novy Collegiate Professor
Professor of Microbiology and Immunology
headshot of Mary ORiordan Mary O'Riordan, PhD
Frederick C Neidhardt Collegiate Professor
Professor of Microbiology and Immunology
Maria Sandkvist M&I-1200x1500.jpeg Maria Sandkvist, PhD
Professor of Microbiology & Immunology
headshot of Pat Schloss Patrick Schloss, PhD
Program Director of Microbiology and Immunology AP&A
Frederick G Novy Collegiate Professor of Microbiome Research and Professor of Microbiology and Immunology
labcoat David H Sherman, PhD
Professor
labcoat Evan Snitkin, PhD
Associate Professor of Microbiology and Immunology
Associate Professor of Internal Medicine
swanson-michele Michele Swanson, PhD
Professor of Microbiology and Immunology
Director of Postdoctoral Studies
young-vince Vincent B Young, MD, PhD
William Henry Fitzbutler Collegiate Professor of Internal Medicine
Professor of Internal Medicine
Professor of Microbiology and Immunology
shenoy-anukul Anukul Shenoy, PhD
Assistant Professor of Microbiology
Immunology