Back to Research
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AI & Machine Learning -
Applications to Complex Genetic Diseases -
4D Nucleome -
Genomics, Gene Regulation & Epigenomics -
Multi-“omics” Integrative Bioinformatics -
Protein Structure, Proteomics & Alternative Splicing -
Systems Biology & Networks Analysis -
Translational Bioinformatics, Drug Discovery & Pharmacogenomics -
Grants -
Software & Bioinformatics Tools
In 2022, U-M Medical School Department of Computational Medicine & Bioinformatics ranked #4 in NIH Grants for biomedical science departments.
- 18 new awards where DCMB Faculty are PI’s: $9,338.111
- 26 new awards where DCMB are Co-I’s: $58,229.192
- 8 new awards where DCMB faculty are participating without effort $7,891,868
- Grand total of 52 new grants involving DCMB Faculty for $75,459,171
- “High-throughput Inverted Reporter Assay for Characterization of Silencers and Enhancer Blockers”
- “Mobile Element Derived Chromatin Looping Variability in Human Populations”
- “The Biology of Mutant STAT6 in Follicular Lymphoma” with Dr. Malek, U-M Internal Medicine - Division of Hematology/Oncology
- “Uncover the Role of H3.3-G343R Mutation in Shaping the DNA Damage Response, Anti-tumor Immunity and Mechanisms of Resistance in Glioma” with Dr. Castro, U-M Rogel Cancer Center
- “Allele-specific Analysis of Human Epigenome, Transcriptome and High-resolution Chromatin Organization”
- “A consortium-wide modular MPRA resource to assess cellular contexts of T2D variants” with the Broad Institute, MIT and Havard
- “Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression” with Cornell University
- “Expansion of Pancreatias Connectivity Platform and Phenotyping of HANDEL Samples by Cutting-Edge Single Cell Multi-ome Technology” with Vanderbilt University
- “Proposal for the AMP T2D-GENES Data Coordination Center and Web Portal” with the Broad Institute, MIT and Havard
- “The Regulation of Hepatic Metabolic Zonation by the Diabetes Gene TCF7L2” with the University of Texas, Health Science Center at San Antonio
- “Risk of Alzheimer's Disease and Related Dementias from Perinatal Lead Exposure: Brain Region and Cell Type Effects” with Dr. Bakulski, U-M School of Public Health, Epidemiology
- “Craniofacial Skeletal Cell Lineage Plasticity for Reconstituting Stem Cells and their Niches” with the University of Texas
- “Leveraging Spatial Location for Single-Cell Molecular and Morphological Characterization” Student award (F31)
In 2022, DCMB ranked #4 in NIH Grants in Biomedical Science departments.
Two NIH Training Grants
- “Biomedical Informatics and Data Science Training Program (BIDSTP)” - eight funded students per year for five years
Project Directors: Dr. Ivo Dinov and Dr. Maureen Sartor - “Proteogenomics of Cancer Training Program” - seven funded students per year for five years
Project Director: Dr. Alexey Nesvizhskii
NSF Grant
- “IUCRC Phase I University of Michigan Ann Arbor: Center for Data-Driven Drug Development and Treatment Assessment (DATA)” with U-M MIDAS
Department of Defense Grant
- “Data-guided Learning and Control of Higher Order Structures”