DCMB Research
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Translating Theories into Practice

We leverage innovative technologies to investigate how hidden information in genes and biological molecules can further personalize the diagnosis, treatment and prevention of diseases.

Creating Novel AI & Machine Learning Methods to Accelerate Discoveries & Biomedical Research

The research focus of the Department of Computational Medicine and Bioinformatics (DCMB) is to create novel and impactful informatics and computationally based AI and Machine Learning methods, tools, algorithms, and information resources to enable and extend basic and clinical research discoveries and methods. 

Working with our students and post-docs, we provide the ideal environment to learn by creating our research and publishing our impactful findings in leading journals. Our research is supported by the National Institutes for Health (NIH), the National Science Foundation (NSF), the Defense Advanced Research Projects Agency (DARPA), and many non-for-profit Foundations and research organizations.

Our faculty engage in a vast spectrum of bioinformatics and computational biology research, analyzing unanswered questions spanning cancers and neuropsychiatric disorders to metagenomics and translational informatics. There is still much to explore at the intersection of biology, computational science, mathematics and medicine. Our faculty are nationally recognized leaders in this highly interdisciplinary field.

More about DCMB Faculty

DCMB Publications

View a collection of publications from the Department of Computational Medicine & Bioinformatics.

View publications on PubMed

By their very nature, computational medicine and bioinformatics are very collaborative. DCMB and CCMB members are engaged with many U-M partners.

  • Caswell Diabetes Institute
  • Center for Metabolic Diseases
  • College of Pharmacy
  • Eisenberg Family Depression Center
  • Frankel Institute for Heart and Brain Health
  • Health Data
  • Internal Medicine
  • Kellogg Eye Center
  • Michigan Neuroscience Institute
  • Precision Health
  • Radiation Oncology
  • Rogel Cancer Center
  • School of Public Health 
  • Weil Institute for Critical Care
Venn diagram illustrating the interdisciplinary nature of dcmb/ccmb machine learning within various biomedical and research sectors at an academic institution.

Graphic that shows DCMB at the core, surrounded by a ring with the various fields of computational medicine and bioinformatics applications. On the outside are "petals" with the name of collaborating units at U-M: Precision Health, Weill Institute for Critical Care, Eisenberg Family Depression Center, Health Data, School of Public Health, Radiation Oncology, Rogel Cancer Center, College of Pharmacy, Center for Metabolic Diseases, Castell Diabetes Institute, Kellogg Eye Center, Internal Medicine, Michigan Neuroscience Institute, and the Institute for Heart and Brain Health. This graphics looks like a flower with a maize and blue core, and colorful petals.

Researcher Database

Explore DCMB's research profile and collaboration network on the Michigan Experts website, a searchable database of research expertise across disciplines from the University of Michigan’s schools, colleges and institutes.

Research Grants

In 2022, DCMB received nearly $75.5 million in funding for 52 grants from organizations including National Science Foundation (NSF), Department of Defense (DoD) and the National Institutes of Health (NIH), for which DCMB ranked #4 in NIH Grants for biomedical science departments.

BAB in the Lab

BioAssemblyBot®, an ultra precise robot affectionately referred to as "she," makes repetition her core mission. Her infatigable ability to precisely repeat the same test using different samples in mere hours gives time back to our scientists to design the best possible experiments.

Get to Know BAB
Featured News & Stories See all news Portrait of Marissa Dolorfino
Department News
DCMB Graduate Student Marissa Dolorfino receives a four-year fellowship from DOE
Marissa Dolorfino, a Bioinformatics Graduate Program trainee mentored by professor Matthew O’Meara, DCMB, and Terra Sztain-Pedone, College of Pharmacy, was awarded a 4-year Department of Energy Computational Science Graduate Fellowship (DOE CSGF).
Kayvan Najarian speaking at the 2024 DATA meeting at the University of Michigan
Department News
The Center for Data-Driven Drug Development and Treatment Assessment (DATA): Industry Advisory Board meeting and project funding awards announcement
The Center for Data-Driven Drug Development and Treatment Assessment (DATA) held a two-day meeting of its Industry Advisory Board (IAB) on May 16–17, 2024, at the University of Michigan (U-M) in Ann Arbor, Michigan. The goals for the meeting were for the Center’s IAB to award DATA’s 2024–25 research grants, to discuss how the Center can respond to the current trends and industry needs in the areas of AI for drug design and treatment assessment, and to showcase the young scientists trained at the U-M in this field.
Photos of DCMB promoted faculty: Yuanfang Guan, Ph.D., Jie Liu, Ph.D., Ryan Mills, Ph.D., Stephen C.J. Parker, Ph.D., and Arvind Rao, Ph.D.
Department News
Five DCMB faculty are promoted, congratulations!
Five DCMB faculty were promoted. They are Yuanfang Guan, Ph.D., Jie Liu, Ph.D., Ryan Mills, Ph.D., Stephen C.J. Parker, Ph.D., and Arvind Rao, Ph.D. Congratulations!
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Health Lab
Massive study identifies new biomarkers for renal cancer subtypes, improving diagnosis and—eventually—treatment
A study led by University of Michigan Health Rogel Cancer Center researchers identifies novel biomarkers in renal cell carcinomas.
Maya Bose Drawn to Michigan caricature
Department News
Drawn to Michigan Featuring Maya Bose
Drawn to Michigan Featuring Maya Bose - From River Otters to DNA: Her Journey to Computational Medicine and Bioinformatics at U-M!
University of Michigan Girls Who Code logo
Department News
U-M Girls Who Code (GWC) received a Phyllis M. Blackman Innovation Grant to promote "Strengthening Community Partnerships."
This DEI grant will support the Girls Who Code Summer Camp in greater Detroit.