woman in red shirt reads through papers
Genomics, Gene Regulation & Epigenomics

Genomics research is at the center of DCMB’s endeavor to understand the structure, function, and evolution of our genome and its role in variations of biological traits and diseases.

Regulatory genomics and epigenomics research aims to understand how the timing, quantity and variant forms of gene activity are controlled both by regulatory elements in the DNA sequences and by chemicals that bind and modify the DNA and the chromatins. The study of the genome, the regulatory genome and the epigenome together sheds light on the human genome as a dynamic system shaped by DNA sequences that is invariant in an individual’s life span and by chemical modifications through intrinsic and external factors.  

Eventually, we hope that research in these areas will uncover the secret of how the human genome defines our species, the individuals, and their health. 

DCMB faculty members’ research in these areas spans from basic science to clinical applications, as well as the development of tools and methods that enable the advancement of the field.  

This research overlaps with the study of 4D Nucleome and the Application to Complex Genetic Diseases.

The following DCMB/CCMB faculty members work in this area. 
Associated Faculty
Brian Athey Brian D Athey, PhD
Michael Savageau Collegiate Professor
Chair
Department of Computational Medicine and Bioinformatics
Professor of Computational Medicine and Bioinformatics
Professor of Psychiatry
Medical School
Veera Baladandayuthapani Veera Baladandayuthapani, PhD
Jeremy M G Taylor Collegiate Professor of Biostatistics
Chair, Department of Biostatistics
Professor of Biostatistics, School of Public Health
Professor of Computational Medicine and Bioinformatics, Medical School
Profile-AuKinFai-2023.jpg Kin Fai Au, PhD
Professor of Computational Medicine and Bioinformatics
Medical School
Alan Boyle Alan P Boyle, PhD
Associate Professor of Computational Medicine and Bioinformatics
Associate Professor of Human Genetics, Medical School
Ivo Dinov Ivo Dinov, PhD
Henry P Tappan Collegiate Professor of Nursing
Professor of Nursing
Director Academic Program
School of Nursing
Professor of Computational Medicine and Bioinformatics
Medical School
Guan-Yuanfan.jpg Yuanfang Guan, PhD
Professor of Computational Medicine and Bioinformatics
Professor of Internal Medicine, Medical School
labcoat Jeffrey Kidd
Professor of Human Genetics
Professor of Computational Medicine and Bioinformatics
Medical School
Minji Kim Minji Kim, PhD
Assistant Professor of Computational Medicine and Bioinformatics
Medical School
Jacob Kitzman headshot Jacob Kitzman, PhD
Associate Professor of Human Genetics
Associate Chair
Department of Human Genetics
Associate Professor of Computational Medicine and Bioinformatics
Medical School
Cong Ma Cong Ma, PhD
Assistant Professor of Computational Medicine and Bioinformatics
Medical School
headshot of Rajasree Menon Rajasree Menon, PhD
Research Scientist
Computational Medicine and Bioinformatics
Medical School
Ryan Mills Ryan E Mills
Program Director of DCMB Computing Infrastructure
Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics
Medical School
Steven Parker Stephen CJ Parker, PhD
Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics
Medical School and Professor of Biostatistics
School of Public Health
Indika Rajapakse Indika Rajapakse, PhD
Professor of Computational Medicine and Bioinformatics, Medical School
Professor of Mathematics, College of Literature, Science, and the Arts
portrait of Arvind Rao Arvind Rao, PhD
Professor of Computational Medicine and Bioinformatics
Professor of Radiation Oncology, Medical School
Professor of Biostatistics, School of Public Health
Maureen Sartor Maureen Sartor, PhD
Co-Director
Bioinformatics Graduate Program
Professor of Computational Medicine and Bioinformatics
Medical School
Professor of Biostatistics
School of Public Health
Elizabeth Katherine Speliotes headshot Elizabeth K Speliotes, MD, PhD, MPH
Keith S Henley M.D. Collegiate Professor of Gastroenterology
Professor of Internal Medicine
Professor of Computational Medicine and Bioinformatics
Associate Director
Medical Scientist Training Program (MSTP) and Program Director
Precision Medicine Program
Medical School
portrait of Alex Tsoi Lam (Alex) C Tsoi, PhD
Assistant Professor of Dermatology
Assistant Professor of Computational Medicine and Bioinformatics
Research Assistant Professor, Mary H Weiser Food Allergy
Medical School and Research Assistant Professor, Biostatistics, School of Public Health
Joshua Welch Joshua Welch, PhD
Associate Professor of Computational Medicine and Bioinformatics, Medical School
Associate Professor of Electrical Engineering and Computer Science, College of Engineering
Yue Zhao Yue Zhao, PhD
Research Assistant Professor
Computational Medicine and Bioinformatics
Medical School