Neurology providers point to a computer screen
BASIC Sleep & Sleep Apnea Projects

Since 2010, our group has investigated multiple aspects of sleep apnea, and more recently, sleep itself, and its associations with stroke and stroke outcomes. The BASIC Sleep Apnea Projects used a portable sleep apnea test to evaluate sleep apnea. Currently funded studies use full, portable polysomnography.

Project Titles

 

  • The epidemiology of sleep apnea in a bi-ethnic stroke population (R01 HL098065)

  • Sleep Apnea Health Disparities in Mexican American Stroke Patients (R01 NS070941)
  • Nocturnal rostral fluid shifts in stroke patients with sleep apnea (R01HL123379)
  • Sleep apnea after stroke: Implications for screening and treatment (R01HL126700)
  • Identifying sleep targets to improve stroke outcomes (R01HL152741)
  • Towards personalized medicine: pathophysiologic contributions to post-stroke sleep apnea (R01HL164755)
Overview

The University of Michigan Stroke Program investigates multiple aspects of post-stroke sleep and sleep apnea among patients in Corpus Christi, Texas.

  • An NHLBI-funded ancillary study assessed the frequency of sleep-disordered breathing after stroke, and the relationship of this sleep disorder to stroke outcomes
  • An NINDS-funded sleep apnea study investigate health disparities related to sleep apnea in stroke patients
  • An NHLBI-funded ancillary study investigated the association between nocturnal rostral fluid shifts and sleep apnea severity
  • An NINDS-funded longitudinal, population-based study of sleep apnea and stroke outcomes was performed to improve the identification and management of important sleep apnea after stroke, provide critical data to plan future clinical trials, and explore a potential target to reduce an important ethnic health disparity
  • An NHLBI-funded ancillary study investigates, using full portable PSG, the association between sleep and recovery after stroke
  • Finally, an NHLBI-funded longitudinal study that enrolls stroke cases and a stroke-free comparison group investigates the pathophysiologic mechanism (endotypes) underlying obstructive sleep apnea
Our Publications

View our publications to read the latest research on sleep and sleep apnea.

View our publications
Sleep Study Staff
Principal Investigators
labcoat Devin L Brown, MD, MS
Professor of Neurology
user Lynda D. Lisabeth, PhD, MPH
Co-Investigators
labcoat Ronald D Chervin, MD, MS
Michael S Aldrich Collegiate Professor of Sleep Medicine
Professor of Neurology and Section Head for Sleep Disorders
Lewis B. Morgenstern Lewis B Morgenstern
Milton and Carolyn Kevreson Research Professor of Neurology
Professor of Neurology
Professor of Neurosurgery
Professor of Emergency Medicine
Professor of Epidemiology
Section Head for Stroke
user Brisa N. Sánchez, PhD user Sehee Kim, PhD user Xu Shi, PhD user Yan Sun, PhD user Joseph Burns, PhD user Scott Sands, PhD