Neurology providers point to a computer screen
BASIC Sleep & Sleep Apnea Projects

Since 2010, our group has investigated multiple aspects of sleep apnea, and more recently, sleep itself, and its associations with stroke and stroke outcomes. The BASIC Sleep Apnea Projects used a portable sleep apnea test to evaluate sleep apnea. Currently funded studies use full, portable polysomnography.

BASIC Sleep Study

This research study involves hundreds of patients with recent stroke or stroke‐like symptoms. This study may benefit you and may help doctors care for future patients with stroke. This research study is being funded by the National Institutes of Health and is only being conducted in Nueces County. 

Sleep disorders are common after stroke. This unique research study will explore how sleep disorders may impact the recovery of patients after stroke. Ultimately, we hope to use this information to provide better treatments for stroke patients.  

Sleep testing provides information about amount of sleep, time spent in different sleep stages, time spent awake after initial sleep, breathing during sleep, and oxygen drops during sleep. Sleep testing can also find a common condition called sleep apnea, where you stop breathing or almost stop breathing multiple times per hour during sleep. 

The sleep study will be performed with a device called the Nox A1. We typically do the testing a week or two after your hospitalization. The Nox A1 monitors your breathing, blood oxygen, leg movements, brain waves, heartbeat (EKG), body position and movement, and surrounding light. This device also records sound to capture your snoring. Sleep studies are usually performed in a sleep laboratory, but we will conduct yours in your home for added convenience.  

There is no charge to you or your insurance company if you participate. You will receive the results of the sleep testing about 3 months after the test. You will also receive $50 to thank you for your participation. 

Project Titles
  • The epidemiology of sleep apnea in a bi-ethnic stroke population (R01 HL098065)
  • Sleep Apnea Health Disparities in Mexican American Stroke Patients (R01 NS070941)
  • Nocturnal rostral fluid shifts in stroke patients with sleep apnea (R01HL123379)
  • Sleep apnea after stroke: Implications for screening and treatment (R01HL126700)
  • Identifying sleep targets to improve stroke outcomes (R01HL152741)
  • Towards personalized medicine: pathophysiologic contributions to post-stroke sleep apnea (R01HL164755)

The University of Michigan Stroke Program investigates multiple aspects of post-stroke sleep and sleep apnea among patients in Corpus Christi, Texas.

  • An NHLBI-funded ancillary study assessed the frequency of sleep-disordered breathing after stroke, and the relationship of this sleep disorder to stroke outcomes
  • An NINDS-funded sleep apnea study investigate health disparities related to sleep apnea in stroke patients
  • An NHLBI-funded ancillary study investigated the association between nocturnal rostral fluid shifts and sleep apnea severity
  • An NINDS-funded longitudinal, population-based study of sleep apnea and stroke outcomes was performed to improve the identification and management of important sleep apnea after stroke, provide critical data to plan future clinical trials, and explore a potential target to reduce an important ethnic health disparity
  • An NHLBI-funded ancillary study investigates, using full portable PSG, the association between sleep and recovery after stroke
  • Finally, an NHLBI-funded longitudinal study that enrolls stroke cases and a stroke-free comparison group investigates the pathophysiologic mechanism (endotypes) underlying obstructive sleep apnea
Our Publications

View our publications to read the latest research on sleep and sleep apnea.

View our publications
Sleep Study Staff
Principal Investigators
labcoat Devin L Brown, MD, MS
Professor of Neurology
user Lynda D. Lisabeth, PhD, MPH
labcoat Ronald D Chervin, MD, MS
Michael S Aldrich Collegiate Professor of Sleep Medicine
Professor of Neurology and Section Head for Sleep Disorders
Lewis B. Morgenstern Lewis B Morgenstern
Milton and Carolyn Kevreson Research Professor of Neurology
Professor of Neurology
Professor of Neurosurgery
Professor of Emergency Medicine
Professor of Epidemiology
user Brisa N. Sánchez, PhD user Sehee Kim, PhD user Xu Shi, PhD user Yan Sun, PhD user Joseph Burns, PhD user Scott Sands, PhD