
Our genome is intricately structured at multiple levels in the cell. However, how these structural aspects affect cellular function and cause disease is largely unknown.
Our researchers are uncovering these mysteries of our genome by employing cutting-edge experimental and computational approaches. Our work encompasses the realms of basic, applied and clinical research. For example, we investigate: the molecular mechanisms driving de novo variants in germ cells; how ‘jumping genes’ or retrotransposons affect the structure our genome function; and how transcriptional regulatory elements direct gene expression at the proper time and space.
We also develop and employ cutting-edge approaches to address these questions including novel single-cell genomics, and super-resolution microscopy, nascent RNA sequencing, massively parallel mutagenesis, and transcriptional assays with big data analysis tools.
Please browse the profiles of the Evolutionary & Population Genetics faculty below to explore the research of individual laboratories.

Professor of Human Genetics
Chair, Department of Human Genetics and Professor of Neurology
Medical School

Associate Professor of Human Genetics
Medical School

Program Director, Bioinformatics Graduate Program
Professor of Human Genetics
Professor of Psychiatry
Research Professor, Michigan Neuroscience Institute and Professor of Computational Medicine and Bioinformatics
Medical School

Professor of Human Genetics
Professor of Internal Medicine
Medical School

Warner-Lambert/Parke-Davis Professor of Medicine
Professor of Internal Medicine
Professor of Human Genetics
Professor of Pediatrics
Medical School and Research Professor
Life Sciences Institute

Associate Professor of Urology
Associate Professor of Obstetrics and Gynecology
Medical School

Associate Professor of Pediatrics
Medical School

Medical School

Associate Chair
Department of Human Genetics
Associate Professor of Computational Medicine and Bioinformatics
Medical School

Professor of Computational Medicine and Bioinformatics
Medical School

Research Associate Professor
Michigan Neuroscience Institute
Medical School

Medical School

Assistant Professor of Human Genetics and Associate Director Academic Program, PIBS, Medical School

Professor of Human Genetics
Professor of Neurology
Medical School

Professor of Computational Medicine and Bioinformatics
Professor of Human Genetics

Professor of Human Genetics
Professor of Internal Medicine and Program Director
PhD Graduate Program in Genetics and Genomics
Medical School

Medical School

Associate Chair, Department of Human Genetics
Program Director, Human Genetics
Associate Professor of Obstetrics and Gynecology
Associate Professor of Urology
Medical School

Medical School

Professor of Human Genetics
Medical School and Professor of Biostatistics
School of Public Health

Assistant Professor of Human Genetics
Medical School

Associate Professor of Ophthalmology and Visual Sciences
Associate Professor of Pathology
Associate Professor of Human Genetics
Medical School

Associate Professor of Human Genetics
Associate Chair, Department of Human Genetics and Program Director, Human Genetics, Medical School

Professor of Pediatrics
Professor of Human Genetics
Medical School

Professor of Neurology
Associate Chair for Research
Department of Neurology
Medical Director
Neurology and Professor of Human Genetics
Medical School

Professor of Human Genetics
Associate Medical Director
Molecular Diagnostics Laboratory
Program Assistant
MGP Fellowship Director
Medical School