Human Genetics Research
MPHOTO-HumnGeneticsHdsGrps24(51)_.jpg

Mapping the Future of Human Genetics

We're evolving the field through research in Genome Structure and Function, Population Genetics and more.

One of the most remarkable aspects of our scientific community is the diversity of research topics we explore. To tackle questions across varied topics, we balance the use of classical approaches with new, cutting-edge experimental and computational techniques. We also leverage a host of model systems including yeast, zebrafish, mouse, dogs, and human populations. 

Unifying our diverse research, and centering our scientific community, is a shared drive to understand how genomes function, how they change over time and across environments, and how perturbations in genome sequences cause single-gene and complex diseases.

Dive Deep Into the Literature

Michigan Experts is a searchable database of research expertise across disciplines from several schools/colleges or institutes at the University of Michigan. Please explore the U-M Medical School Department of Human Genetics' research profile and collaboration network on the Michigan Experts website.

PubMed® comprises more than 37 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full text content from PubMed Central and publisher web sites. Please explore the Department of Human Genetics' publications on the PubMed Central website. View select department publications since 2019.

Work With Us

Join a cohesive and highly interactive community of investigators and educators with research programs in diverse areas of genetics and genomics.

See Open Positions
Awards & Publication Announcements

Emails to this group will be sent to the Department of Human Genetics Public Relations Team to announce new press in research and education.

Contact our PR team
Featured News & Stories See all news red cancer cell on red background
Health Lab
Researchers identify roles of key genes in colon cancer development
Researchers used mouse models and studies of colorectal cancer tissues to show that loss of SOX9 gene promotes tumor progression and the pathway it regulates can be a potential target for future treatments.
Photo of Dr. Jun Li
Department News
Connecting the Dots with Dr. Jun Li
The U-M RNA Center interviewed Dr. Jun Li, highlighting his collaborations with several U-M initiatives, centers, and institutions and contributions as a member of several committees and advisory panels at the U-M Medical School and beyond.
Department News
Now Hiring! Research Administrator Intermediate
​We have posted a​n exciting Research Administrator Intermediate position with​in ​t​he Department of Human Genetics at the University of Michigan Medical School.
sperm moving to cell all blue and cell red
Health Lab
Battle of the sex chromosomes
A study from University of Michigan researchers has uncovered the mechanism behind the arms race for mouse X and Y bearing sperm to fertilize an egg.
Department News
PNAS Comments on Dr. Martin Arlt's Study
PNAS comments on Dr. Martin Arlt's study "Reenacting a mouse genetic evolutionary arms race in yeast reveals that SLXL1/SLX compete with SLY1/2 for binding to Spindlins" on March 3, 2025.
Department News
Dr. Samantha Regan Receives the 2025 Young Investigator Award
Dr. Samantha Regan is named 2025 Young Investigator from the ASXL Rare Research Endowment (ARRE) Foundation.