More articles about: Basic Science and Laboratory Research

New map of the ovary provides a deeper understanding of how oocytes interact with the surrounding cells during the normal maturation process, and how the function of the follicles may break down in aging or fertility related diseases.

A recent U-M study uncovers a pathway utilized during normal wound healing that has the potential to reverse idiopathic pulmonary fibrosis.

A new collaborative study, examined the interaction between three naturally occurring gases — nitric oxide (NO), oxygen, and H2S — during generation of new blood vessels, called angiogenesis.

Researchers open new leads in anti-HIV drug development, using a compound found in nature

Study focuses on Hippo signaling pathway as critical link between fibrosis, vascular dysfunction, and sex bias in systemic sclerosis

Bacteria in the mouth may play a role in survival from idiopathic pulmonary fibrosis (IPF).

A new study links two autism-associated genes together for the first time, potentially revealing a mechanism behind brain changes seen in people with autism.

A prospective study published in the journal Lancet Microbe provides more clarity on which patient populations are at higher risk for prolonged infections — and hints that this fear is likely unwarranted.

A study from the University of Michigan Medical School developed off-switches useful for improving the safety of the Type I-C/Cas3 gene editor.

Research from Michigan Medicine experts is shedding light and potentially expanding options for patients living with an aggressive childhood cancer.

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment, also finding a way to deliver immunotherapy’s cancer-killing impact without the unwelcome side effect.

Itaconate shows promise in reducing inflammation for several conditions

By studying first-year college students’ experiences and backgrounds, scientists may have discovered a way to go beyond genetics to predict which students might be more or less vulnerable to stress-related depression.

A Michigan Medicine expert breaks down what ulnar neuropathy is and how electrodiagnostic studies can assess severity and guide management, which can sometimes include conservative treatment and education on how to protect the nerve.

Through a series of experiments in non-human primates, mice and humans, a multi-institutional team led by researchers from Michigan Medicine and Rush University found that the immune protein soluble urokinase plasminogen activator receptor, or suPAR, is an important link between viral infections and proteinuria; the elevation of protein in the urine is known to cause glomerulopathy, a common form of kidney disease.