More articles about: Basic Science and Laboratory Research

Why smokers have a higher chance of developing pancreatic cancer and why they tend to have worse outcomes than nonsmokers, according to a new study by University of Michigan Health Rogel Cancer Center.

New research discovers how cells prevent RNA traffic jams under stress, which could help fight disease

Patricia and Jerry Wagner have provided ongoing, dedicated support to the Heinz C. Prechter Bipolar Research Program at University of Michigan Heatlh.

Study reveals how a popular fentanyl additive, xylazine, affects breathing and heart rate.

Researchers from University of Michigan have identified pivotal roles for a pair of virus-like proteins and their effect on how cells self-regulate and respond to stress. These proteins are implicated in several cancers and neurodegenerative diseases

High levels of triglycerides, the most common type of fat in the body and the foods you eat, directly cause abdominal aortic aneurysms, according to a study in mice. A drug candidate lowered triglyceride levels by up to 50% and prevented aneurysm formation, showing promise as a treatment avenue. 

An international research team finds that the human gut is a site of rapid change, with recent and important deviations from other mammals.

Michigan Medicine researchers identify the function behind mysterious variants for a gene linked to colon cancer.

Saiontz family's gift to U-M's Mary H. Weiser Food Allergy Center boosts innovative research, education, and care for people living with food allergies.

Researchers at Michigan Medicine have uncovered a key mechanism that regulates blood pressure and vascular remodeling in people with a genetic variant linked to high blood pressure.

A study explains the genetic underpinnings of a rare and aggressive form of ovarian cancer – and offers a potential pathway for new treatments.

University of Michigan Health Rogel Cancer Center scientists identified a gene that plays a key role in prostate cancer cells that have transitioned to a more aggressive, treatment-resistant form. The gene can be indirectly targeted with an existing class of drugs, suggesting a potential treatment strategy for patients with aggressive subtypes of prostate cancer.

The University of Michigan team identified herpesvirus saimiri, which infects the T cells of squirrel monkeys, as a source of proteins that activate pathways in T cells that are needed to promote T cell survival.

New research work discovers that the presence of dead members of C. elegans has profound behavioral and physiological effects, leading the worms to more quickly reproduce and shorten their lifespans.

Researchers have discovered a new molecular process that occurs when donor hearts are preserved in cold storage which contributes to failure after transplant, a study in both humans and animals shows. Fortunately, therapy that is typically prescribed for high blood pressure can target this process to reduce cold preservation associated with cardiac injury. This discovery has potential to improve the consistent function of donor hearts and extend the distance they can be safely transported in cold storage.