More articles about: Basic Science and Laboratory Research

Phrenic neuropathy is a condition that impacts the nerve around the diaphragm making it harder to breathe, especially in situations such as lying down or being in water. The condition is treatable, with surgical intervention, physical therapy or by letting it heal over time.

A low calorie diet and high intensity exercise can reduce nerve damage in prediabetic mice, according to a Michigan Medicine study.

University of Michigan researchers may have found that the solution to prevent people from dying from a fentanyl overdose may be found within fentanyl's own chemistry.

New research has discovered why some cancers don’t respond to immunotherapy treatment: A metabolite transporter within the tumor microenvironment blocks a key type of tumor cell death integral to immune response.

A study hints at how complex introducing yourself to another can be, using a mouse model to uncover the brain processes behind nonsexual social approach and contact.

Dementia doesn’t just erode memory – it also changes behavior and mental health. A new study shows the brain’s salience network and tau protein may be involved.

Researchers have developed a new model to help predict treatment response in patients with bladder cancer. 

A study shows that disulfiram, known for causing severe hangover symptoms by blocking alcohol breakdown, also inhibits the inflammatory NLRP3 complex.

Researchers have uncovered a key reason why a typically normal protein goes awry and fuels cancer. They found the protein NSD2 alters the function of the androgen receptor, an important regulator of normal prostate development.

Using the Ab38 antibody to target the CD38 enzyme could be a new gateway to treat and prevent fibrosis for patients with systemic sclerosis.

Targeting and blocking the sCD13 protein from interacting with the B1R protein can pave the way for new fibrosis and systemic sclerosis treatments.

A research team is investigating how metabolism – the process by which cells turn sugars, fats and proteins into energy – is used to make NETs in regards to antiphospholipid syndrome.

An investigator looks at the hidden influence of Vascular Endothelial Growth Factor, or VEGF, in a deadly form of Castleman disease

Research finds that adults living with cerebral palsy had a very high occurrence of pain, with 90% having a pain history and 74% having multiple diagnoses of pain coming from different origins such as the lower back, irritable bowels, joint arthritis and chronic headaches.

A network of proteins found in the central nervous system could be harnessed to increase the effectiveness, and reduce the side effects, of diabetes and weight-loss drugs such as Ozempic and Mounjaro, according to research from the University of Michigan Life Sciences Institute.