Translational Neuro Image
Translational Neuro-Oncology Labs

The Translational Neuro-Oncology Laboratories aim to discover the cellular, molecular, and mathematical basis underlying the growth patterns of malignant brain tumors (glioma, GBM), and the interactions between cancer cells and the tumor microenvironment. Investigators in the Translational Neuro-Oncology Laboratories are also developing new immunotherapies for primary and metastatic brain cancer. Research efforts range from basic immunobiologic mechanisms to translational immune-therapeutics.

Pioneering work from the Translational Neuro-Oncology Laboratories has led to an FDA-approved Phase I clinical trial for malignant brain cancer that is ongoing within the U-M Medical School Department of Neurosurgery. 

Visit the Castro-Lowenstein Lab

Research Faculty
profile-maria-castro-2023 Maria Castro, PhD
R C Schneider Collegiate Professor
Professor of Neurosurgery
Professor of Cell and Developmental Biology
Co-Director, Brain Tumor Research and Translational Neuro-Oncology Laboratories
Pedro Lowenstein Pedro Lowenstein
Richard Schneider Collegiate Professor
Assistant Chair
DEI in Research
Professor of Neurosurgery
Professor of Cell and Developmental Biology
Translational Neuro-Oncology Laboratories