![2019 Crosby Lab Image](https://medschool.umich.edu/sites/default/files/styles/large_16_9/public/2023-10/CrosbyLab%282019%29.jpeg?h=e35444e9&itok=VDc-k1l9)
The Crosby Neurosurgical Laboratories have two main areas of research focus: cerebrovascular disease and central nervous system (CNS) tumors. Cerebrovascular studies focus on understanding mechanisms of brain injury in hemorrhagic and ischemic stroke, and the effects of neurological disease on the blood-brain barrier.
CNS tumor research centers on the role of cancer stems cells in glioblastoma and medulloblastoma, the stem cell vascular niche, developing new therapies for spine metastatic cancers, and engineering stem cells as inflammatory sensors and vehicles for delivering therapeutics for glioblastoma.
![RICHARD F. KEEP](https://medschool.umich.edu/sites/default/files/styles/wide/public/2023-11/KeepColor.jpg?itok=4JluK0zu)
Crosby-Kahn Collegiate Professor of Neurosurgery and Neuroanatomy
Associate Chair
Department of Neurosurgery
Professor of Molecular and Integrative Physiology
Professor of Neurosurgery and Program Director
Crosby Neurosurgical Laboratories
Associate Chair
Department of Neurosurgery
Professor of Molecular and Integrative Physiology
Professor of Neurosurgery and Program Director
Crosby Neurosurgical Laboratories
![Xing Fan, MD](https://medschool.umich.edu/sites/default/files/styles/wide/public/2023-10/XingFan.jpg?itok=sqS8Lt-3)
Associate Professor of Neurosurgery
Associate Professor of Cell and Developmental Biology
Associate Professor of Cell and Developmental Biology
![profile-ya-hua-2023](https://medschool.umich.edu/sites/default/files/styles/wide/public/2023-11/YaHua.jpg?itok=2Yr6673F)
Research Professor of Neurosurgery
![neurosurgery_guohua_xi](https://medschool.umich.edu/sites/default/files/styles/wide/public/2023-11/Xi.jpg?itok=WXfyDHov)
![profile-jianming-xiang-2023](https://medschool.umich.edu/sites/default/files/styles/wide/public/2023-11/Xiang_Jianming_4x5.jpg?itok=mOrT73BC)
Associate Research Scientist
Neurosurgery
Neurosurgery