a person looking through a microscope

Head & Neck Cancer Research

The department's head and neck oncology research group leads a comprehensive, multidisciplinary research program integrating advanced molecular genetics, immuno-oncology, and patient-centered clinical care. 

Their translational laboratories are pioneering liquid biomarker development for early detection and surveillance, while leveraging spatial transcriptomics and metabolomics to dissect the tumor microenvironment and its role in progression and treatment resistance. A particular focus is placed on understanding the tumor microenvironment in response to immunotherapy and mechanisms of treatment resistance. The group’s work spans bench-to-bedside translation, with robust clinical trial activity informed by genomic, transcriptomic, and spatial data. 

Additionally, investigators are committed to improving outcomes through innovations in shared decision-making and value-based care, ensuring that scientific advances are tightly integrated with patient needs and healthcare system impact.

Our Head and Neck Oncology Program includes experts from 13 departments and five schools within the University of Michigan. Together this dedicated group conducts head and neck cancer research that includes basic, clinical, behavioral, population and translational research. 

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Our Team

headshot of Chad Brenner

J Chad Brenner, PhD, MSE

Associate Professor of Otolaryngology-Head and Neck Surgery
Associate Professor of Pharmacology
Cellular and Molecular Biology Academic Program Director
Medical School
Marisa Buchakjian

Marisa Buchakjian, MD, PhD

Clinical Assistant Professor of Otolaryngology-Head and Neck Surgery
Head and Neck Surgical Oncology
Microvascular Reconstruction Fellowship Director
Medical School
David Forner

David Forner, MD, MSc

Clinical Assistant Professor of Otolaryngology-Head and Neck Surgery
Otolaryngology Education Lead
Medical School
Molly Heft Neal, MD

Molly E Heft Neal, MD

Clinical Assistant Professor of Otolaryngology-Head and Neck Surgery
Otolaryngology-Head and Neck Surgery Associate Chair At-Large
Otolaryngology Education Lead
Medical School
profile-scott-mclean-2019

Scott Alan McLean, MD, PhD, FACS

Clinical Associate Professor of Otolaryngology-Head and Neck Surgery
Medical School
Jeff Moyer

Jeffrey S Moyer, MD, MS, FACS

Shan R Baker M.D. Legacy Professor of Facial Plastic and Reconstructive Surgery
Professor of Otolaryngology-Head and Neck Surgery
Clinical Physician Lead for Otolaryngology
Facial Plastic and Reconstructive Surgery Division Chief
Facial Plastics and Reconstructive Surgery Fellowship Co-Director
Facial Cosmetic Surgery Center Medical Director
Otolaryngology-Head and Neck Surgery and Associate Chair of Clinical Programs
Medical School
2019-Prince-Mark.jpeg

Mark E P Prince, MD, FRCS(C), FACS

Charles J Krause M.D.
Legacy Professor of Otolaryngology
Chair, Department of Otolaryngology-Head and Neck Surgery
Professor of Otolaryngology-Head and Neck Surgery and Otolaryngology
Adult Service Chief
Medical School
Pratyusha Yalamanchi

Pratyusha Yalamanchi, MD, MBA

Clinical Assistant Professor of Otolaryngology-Head and Neck Surgery
Medical School