Professor of Computational Medicine and Bioinformatics
Professor of Internal Medicine
[email protected]
Available to mentor
Yuanfang Guan, PhD
Professor
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Ph.D., Molecular BiologyPrinceton University, Princeton, NJ, 2010
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BS, BiologyThe University of Hong Kong, Hong Kong, 2005
The Guan lab's research focus is machine learning in biology and medical fields.
Guan Lab
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Causey JL, Li K, Chen X, Dong W, Walker K, Qualls JA, Stubblefield J, Moore JH, Guan Y, Huang X. IEEE/ACM Trans Comput Biol Bioinform, 2022 19 (2): 1165 - 1172.Journal ArticleSpatial Pyramid Pooling With 3D Convolution Improves Lung Cancer Detection.
DOI:10.1109/TCBB.2020.3027744 PMID: 32991288 -
Causey JL, Li K, Chen X, Dong W, Walker K, Qualls JA, Stubblefield J, Moore JH, Guan Y, Huang X. IEEE/ACM Trans Comput Biol Bioinform, 2022 19 (2): 1165 - 1172.Journal ArticleSpatial Pyramid Pooling With 3D Convolution Improves Lung Cancer Detection.
DOI:10.1109/TCBB.2020.3027744 PMID: 32991288 -
Bushart DD, Zalon AJ, Zhang H, Morrison LM, Guan Y, Paulson HL, Shakkottai VG, McLoughlin HS. Cerebellum, 2021 Feb; 20 (1): 41 - 53.Journal ArticleAntisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel-Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3.
DOI:10.1007/s12311-020-01179-7 PMID: 32789747 -
Bushart DD, Zalon AJ, Zhang H, Morrison LM, Guan Y, Paulson HL, Shakkottai VG, McLoughlin HS. Cerebellum, 2021 Feb; 20 (1): 41 - 53.Journal ArticleAntisense Oligonucleotide Therapy Targeted Against ATXN3 Improves Potassium Channel-Mediated Purkinje Neuron Dysfunction in Spinocerebellar Ataxia Type 3.
DOI:10.1007/s12311-020-01179-7 PMID: 32789747 -
Wang X, Guan Y. Med Res Rev, 2021 Jan; 41 (1): 5 - 28.Journal ArticleCOVID-19 drug repurposing: A review of computational screening methods, clinical trials, and protein interaction assays.
DOI:10.1002/med.21728 PMID: 32864815 -
Wang X, Guan Y. Med Res Rev, 2021 Jan; 41 (1): 5 - 28.Journal ArticleCOVID-19 drug repurposing: A review of computational screening methods, clinical trials, and protein interaction assays.
DOI:10.1002/med.21728 PMID: 32864815 -
Xiao Y, Wang X, Zhang H, Ulintz PJ, Li H, Guan Y. Nat Commun, 2020 Sep 8; 11 (1): 4469Journal ArticleFastClone is a probabilistic tool for deconvoluting tumor heterogeneity in bulk-sequencing samples.
DOI:10.1038/s41467-020-18169-2 PMID: 32901013 -
Xiao Y, Wang X, Zhang H, Ulintz PJ, Li H, Guan Y. Nat Commun, 2020 Sep 8; 11 (1): 4469Journal ArticleFastClone is a probabilistic tool for deconvoluting tumor heterogeneity in bulk-sequencing samples.
DOI:10.1038/s41467-020-18169-2 PMID: 32901013
Department News
Five DCMB faculty were promoted. They are Yuanfang Guan, Ph.D., Jie Liu, Ph.D., Ryan Mills, Ph.D., Stephen C.J. Parker, Ph.D., and Arvind Rao, Ph.D. Congratulations!