Patricia S Yaeger Collegiate Professor of Molecular, Cellular and Developmental Biology
Professor of Molecular, Cellular and Developmental Biology
College of Literature, Science, and the Arts
Professor of Biological Chemistry
[email protected]
Available to mentor
Ursula H Jakob
Professor
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Oleson BJ, Bhattrai J, Zalubas SL, Kravchenko TR, Ji Y, Jiang EL, Lu CC, Madden CR, Coffman JG, Bazopoulou D, Jones JW, Jakob U. Nat Aging, 2024 Jan; 4 (1): 48 - 61.Journal ArticleEarly life changes in histone landscape protect against age-associated amyloid toxicities through HSF-1-dependent regulation of lipid metabolism.
DOI:10.1038/s43587-023-00537-4 PMID: 38057386 -
Ulrich K, Farkas Á, Chan O, Katamanin O, Schwappach B, Jakob U. Mol Cell, 2022 Sep 1; 82 (17): 3226 - 3238.e7.Journal ArticleFrom guide to guard-activation mechanism of the stress-sensing chaperone Get3.
DOI:10.1016/j.molcel.2022.06.015 PMID: 35839781 -
Neal S, Ohtake F, Cuervo AM, Hegde RS, Jakob U, Lazarou M, Gilbert WV, Chen ZJ, Tooze SA, Haber JE, Walters KJ, Hartl FU. Mol Cell, 2022 Apr 21; 82 (8): 1390 - 1397.Journal ArticleQuality Control: Maintaining molecular order and preventing cellular chaos.
DOI:10.1016/j.molcel.2022.04.002 PMID: 35452608 -
Zuily L, Lahrach N, Fassler R, Genest O, Faller P, Sénèque O, Denis Y, Castanié-Cornet M-P, Genevaux P, Jakob U, Reichmann D, Giudici-Orticoni M-T, Ilbert M. mBio, 2022 Apr 26; 13 (2): e0325121Journal ArticleCopper Induces Protein Aggregation, a Toxic Process Compensated by Molecular Chaperones.
DOI:10.1128/mbio.03251-21 PMID: 35289645 -
Cable J, Weber-Ban E, Clausen T, Walters KJ, Sharon M, Finley DJ, Gu Y, Hanna J, Feng Y, Martens S, Simonsen A, Hansen M, Zhang H, Goodwin JM, Reggio A, Chang C, Ge L, Schulman BA, Deshaies RJ, Dikic I, Harper JW, Wertz IE, Thomä NH, Słabicki M, Frydman J, Jakob U, David DC, Bennett EJ, Bertozzi CR, Sardana R, Eapen VV, Carra S. Ann N Y Acad Sci, 2022 Apr; 1510 (1): 79 - 99.Journal ArticleTargeted protein degradation: from small molecules to complex organelles-a Keystone Symposia report.
DOI:10.1111/nyas.14745 PMID: 35000205 -
Beaufay F, Amemiya HM, Guan J, Basalla J, Meinen BA, Chen Z, Mitra R, Bardwell JCA, Biteen JS, Vecchiarelli AG, Freddolino PL, Jakob U. Sci Adv, 2021 Dec 24; 7 (52): eabk0233Journal ArticlePolyphosphate drives bacterial heterochromatin formation.
DOI:10.1126/sciadv.abk0233 PMID: 34936433 -
Königstorfer A, Ashby LV, Bollar GE, Billiot CE, Gray MJ, Jakob U, Hampton MB, Winterbourn CC. Pathog Dis, 2021 Jan 9; 79 (1):Journal ArticleInduction of the reactive chlorine-responsive transcription factor RclR in Escherichia coli following ingestion by neutrophils.
DOI:10.1093/femspd/ftaa079 PMID: 33351093 -
Ulrich K, Schwappach B, Jakob U. Biol Chem, 2021 Feb 23; 402 (3): 239 - 252.Journal ArticleThiol-based switching mechanisms of stress-sensing chaperones.
DOI:10.1515/hsz-2020-0262 PMID: 32990643