Robert T Kennedy

portrait of Robert T. Kennedy
Hobart H Willard Distinguished University Professor of Chemistry
Professor of Chemistry
College of Literature, Science, and the Arts
Professor of Pharmacology
Medical School
[email protected]
Available to mentor
Robert T Kennedy
portrait of Robert T. Kennedy
Professor
  • About
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  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Robert Kennedy is a Professor of Chemistry and Pharmacology. His research interests are in bioanalytical chemistry with an emphasis on microfluidics, mass spectrometry, chromatography, and electrophoresis. He develops these methods to study neurotransmitter dynamics in vivo, hormone secretion, and for high-throughput experimentation.

    Links

    • My Background

    Qualifications

    • PhD
      University of North Carolina-Chapel Hill, United States
      1984 - 1988

    Center Memberships

    • Center Member
      Caswell Diabetes Institute

    Research Overview

    We develop and apply bioanalytical methods for studying hormone and neurtransmitter secretion. We develop microfluidic chips to culture cells and integrate methods to measure releasate. We also coupling sampling probes to analytical methods for in vivo brain chemical measurements. We develop metabolomics methods for studying biological systems. We have focused LC-MS/MS, capillary electrophoresis, and sensors for analysis. We have applied to study of islets of Langerhans and various rodent models in the brain.

    Recent Publications

    See All Publications
    • Journal Article
      Utilizing Venturi effect for automated high-throughput droplet-MS from well plates.
      Murray BE, Diehl RC, Pott M, Holland-Moritz DA, Narayan ARH, Kennedy RT. Analyst, 2026 Mar 16; DOI:10.1039/d6an00065g
      PMID: PMC12990301
    • Journal Article
      A 3‑D Printed Millifluidic Reactor for Continuous Flow Photocatalysis in the Teaching Laboratory
      Snyder RT, Wortman AK, Xin Y, Penabad LI, Rich LC, Schindler CS, Kennedy RT, Stephenson CRJ. Journal of Chemical Education, 2026 Feb 20; DOI:10.1021/acs.jchemed.5c01125
    • Journal Article
      Neurochemical and Neurophysiological Effects of Intravenous Administration of N,N-Dimethyltryptamine in Rats
      Glynos NG, Huels ER, Groenhout T, Raghu A, Nelson A, Kim Y, Zeid AM, Liu T, Mashour GA, Kennedy RT, Pal D. Journal of Neuroscience the Official Journal of the Society for Neuroscience, 2026 Feb 4; 46 (5): DOI:10.1523/JNEUROSCI.0742-24.2025
      PMID: 41419333
    • Journal Article
      Rapid analysis of terpenes produced by fermentation using flow injection analysis coupled to APCI MS
      Murray BE, Pott M, Beekwilder J, Kennedy RT. Analytical Methods, 2026 Jan 1; DOI:10.1039/d5ay02027a
    • Journal Article
      Sampling Probes Microfabricated from Parylene-C for In Vivo Neurochemical Monitoring
      White T, Bain I, Cain CN, Popov P, Evans CR, Kennedy RT. ACS Measurement Science Au, 2025 Dec 17; 5 (6): 879 - 889. DOI:10.1021/acsmeasuresciau.5c00102
    • Journal Article
      Improving the Detection of Analyte Degeneracies in Untargeted Liquid Chromatography-Tandem Mass Spectrometry Data.
      Cain CN, Ma C-H, Popov P, Kennedy RT. Anal Chem, 2025 Dec 9; 97 (48): 26439 - 26448. DOI:10.1021/acs.analchem.5c03704
      PMID: PMC12961633
    • Journal Article
      Phenotyping and Selection of Cells Using Mass Spectrometry and a Microfluidic Droplet Printer
      Mavrakis E, Knecht GT, Unger MJ, Narayan ARH, Kennedy RT. Analytical Chemistry, 2025 Dec 9; 97 (48): 26607 - 26615. DOI:10.1021/acs.analchem.5c05032
    • Journal Article
      Detection of Neuronal Glutamate in Brain Extracellular Space In Vivo Using Microdialysis and Metabolic Labeling with Glutamine
      Hershey ND, Popov P, Oliver N, Dugan CE, Kennedy RT. ACS Chemical Neuroscience, 2025 Sep 3; 16 (17): 3398 - 3409. DOI:10.1021/acschemneuro.5c00518
      PMID: 40838767