Matthias Truttmann PhD
Assistant Professor of Molecular and Integrative Physiology
[email protected]

Available to mentor
Matthias Truttmann PhD
Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Qualifications
    • Post Doctoral Research Fellow
      Boston Children's Hospital, Biochemistry / Molecular Biology / Cell Biology, 2018
    • Post Doctoral Research Fellow
      Whitehead Institute for Biomedical Research, Biochemistry / Molecular Biology / Cell Biology, 2016
    • Post Doctoral Research Fellow
      Massachusetts Institute of Technology, MIT Learning and Teaching Lab, 2015
    • Post Doctoral Research Fellow
      University of Basel, Biozentrum, Infection Biology / Systems Biology, 2011
    Center Memberships
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    • Center Member
      Rogel Cancer Center
    Research Overview

    Post-translational regulation of chaperone function in aging and aging-associated diseases

    Protein AMPylation in the context of protein aggregation, protein folding and protein quality control

    Genetically encoded, protein aggregation-associated diseases

    De novo generation of camelid nanobodies

    Recent Publications See All Publications
    • Journal Article
      TSWIFT, a novel method for iterative staining of embedded and mounted human brain sections.
      Porter CM, Tabler S, Choi S, Truttmann MC. Sci Rep, 2024 Jun 3; 14 (1): 12688 DOI:10.1038/s41598-024-63152-2
      PMID: 38830987
    • Presentation
      Targeting FICD-mediated protein AMPylation in mammalian proteostasis regulation
      Truttmann M. 2024 Nov 19;
    • Additional Scholarship
      Data from GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function
      Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. 2024 Nov 1; DOI:10.1158/1541-7786.c.7520410
    • Additional Scholarship
      Supplementary Figure S1 from GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function
      Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. 2024 Nov 1; DOI:10.1158/1541-7786.27435436
    • Additional Scholarship
      Supplementary Figure S2 from GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function
      Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. 2024 Nov 1; DOI:10.1158/1541-7786.27435433
    • Additional Scholarship
      Supplementary Figure S3 from GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function
      Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. 2024 Nov 1; DOI:10.1158/1541-7786.27435427
    • Additional Scholarship
      Supplementary Figure S4 from GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function
      Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. 2024 Nov 1; DOI:10.1158/1541-7786.27435424
    • Additional Scholarship
      Supplementary Figure S5 from GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function
      Ray P, Jaiswal S, Ferrer-Torres D, Wang Z, Nancarrow D, Curtin M, Martinho MS, Lacy SM, Kasturirangan S, Thomas D, Spence JR, Truttmann MC, Lagisetty KH, Lawrence TS, Wang TD, Beer DG, Ray D. 2024 Nov 1; DOI:10.1158/1541-7786.27435418