Martin Myers

Martin Myers
Marilyn H Vincent Professor of Diabetes Research
Director of the Michigan Diabetes Initiative
Professor of Internal Medicine
Professor of Molecular and Integrative Physiology
Medical School
University of Michigan Medical School
Internal Medicine
2800 Plymouth Rd., NCRC Bldg 20
Ann Arbor, MI 48109
Available to mentor
Martin Myers
Martin Myers
Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Dr. Myers received his undergraduate degree in Molecular Biology (summa cum laude) at Princeton University in 1988 and his M.D. and Ph.D. (Cell Biology) degrees from Harvard Medical School in 1997. He joined the faculty at the Joslin Diabetes Center at Harvard Medical School in 1997, where he began to focus his independent research laboratory on mechanisms of leptin receptor signaling and links to the regulation of mammalian physiology. In 2004, Dr. Myers moved to the University of Michigan as a Michigan Biomedical Sciences Scholar and joined the faculty of Internal Medicine and Molecular and Integrative Physiology. Dr. Myers is the Director of the Elizabeth Weiser Caswell Diabetes Institute and the Michigan Diabetes Research Center.

    Dr. Myers has been recognized with numerous awards and accolades. He received the Michigan Biomedical Sciences Scholar Award in 2004, was elected to the ASCI in 2005, received the Jerome Conn Award for Excellence in Research in 2006, and the American Diabetes Association’s Outstanding Scientific Achievement Award in 2010.

    Qualifications

    • Postdoctoral Fellow
      Harvard Medical School/Joslin Diabetes Center, Boston, United States
      1997 - 1997
      Postdoctoral Research
    • MD
      Harvard University, Cambridge, United States
      1988 - 1997
    • PhD
      Harvard University, Cambridge, United States
      1990 - 1997
    • AB
      Princeton University, Princeton, NJ, United States
      1984 - 1988

    Center Memberships

    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Caswell Diabetes Institute

    Research Overview

    Dr. Myers’ research focuses on how the central nervous system controls processes that enable the body to control blood glucose and body weight, and how problems in these pathways contribute to the development of insulin resistance and diabetes. His laboratory focuses on the crucial roles played by nerve centers in the unconscious part of the brain — including regions that control food intake and metabolism to regulate body weight, and “glycemic control centers” that regulate the body’s ability to control blood sugar.

    Recent Publications

    See All Publications
    • Journal Article
      Increased leptin signaling drives the response of hypothalamic LepRb neurons to diet-induced obesity.
      Dell'Orco J, Pan W, Allison MB, Tomlinson AJ, Wean J, Sabatini PV, Rhodes CJ, Olson DP, Myers MG, Goforth PB. Mol Metab, 2026 May 2; 102378 DOI:10.1016/j.molmet.2026.102378
      PMID: 42082152
    • Journal Article
      A uniquely leptin sensitive hypothalamic neuron population limits hyperphagia and weight gain in diet-induced obesity.
      Belmont-Rausch DM, Kapel BS, Tomlinson AJ, Ding C, Duensing AM, Coester B, Mathiesen CV, Cabot L, Brown JM, Kruse CH, Clemmensen C, Schwartz MW, Fenselau H, Myers MG, Pers TH. bioRxiv, 2026 Mar 29; DOI:10.64898/2026.03.26.714161
      PMID: PMC13041805
    • Preprint
      Molecularly defined subpopulations of leptin receptor neurons dissociate the control of food intake from blood pressure.
      Duensing AM, Belmont-Rausch D, Tomlinson AJ, Crowley A, Sass F, Heaton E, Coester B, Brown JM, Hassan S, Wu Z, Qi N, Olson DP, Sabatini PV, Myers MG, Pers TH. 2026 Mar 26; DOI:10.64898/2026.03.26.714551
      PMID: 41929005
    • Journal Article
      Neuronal SEL1L-HRD1 ER-associated degradation is essential for motor function and survival in mice.
      Torres M, Lu Y, Pederson B, Wang H, Gretzinger A, Lin L, Hwang J, Chen X, Rupp AC, Tomlinson AJ, Scott AJ, Zhao Z, Wahl DR, Myers M, Lyssiotis CA, Qi L. J Clin Invest, 2026 Feb 19; DOI:10.1172/JCI196819
      PMID: 41712288
    • Journal Article
      Author Correction: Paraventricular, subparaventricular and periventricular hypothalamic IRS4-expressing neurons are required for normal energy balance (Scientific Reports, (2020), 10, 1, (5546), 10.1038/s41598-020-62468-z)
      Sutton Hickey AK, Gonzalez IE, Sadagurski M, Rajala M, Lu C, Allison MB, Adams JM, Myers MG, White MF, Olson DP. Scientific Reports, 2025 Dec 1; 15 (1): DOI:10.1038/s41598-025-85804-7
      PMID: 39966516
    • Journal Article
      Control of physiologic glucose homeostasis via hypothalamic modulation of gluconeogenic substrate availability
      Su J, Hashsham A, Kodur N, Burton C, Mancuso A, Singer A, Wloszek J, Tomlinson AJ, Yacawych WT, Flak JN, Lewis KT, Oles LR, Mori H, Bozadjieva-Kramer N, Turcu AF, MacDougald OA, Myers MG, Affinati AH. Molecular Metabolism, 2025 Sep 1; 99: DOI:10.1016/j.molmet.2025.102216
      PMID: 40684983
    • Journal Article
      Report of the 2023 Mary Tyler Moore Vision Initiative Workshop
      Levine SR, Markel DS, Myers MG, Barunas R, Sun JK, Chang DS, Maguire MG, Vujosevic S, Fort PE, Atkinson M, Baschiera F, Gates C, Hunt JM, King GL, Kretzler M, Lai P, Lewis D, Luhmann UFO, McLeod S, Oxenreiter C, Unsworth S, Chambers W, Aiello LP, Ehrlich J, German CL, Tadayoni R, Wolf RM, Silva P, Carlson E, Gott B, Oxenreiter M, Sexton N, Das A, Gardner TW. Translational Vision Science and Technology, 2025 Jul 1; 14 (7): DOI:10.1167/tvst.14.7.11
      PMID: 40679331
    • Preprint
      Neuronal SEL1L-HRD1 ERAD regulates one-carbon metabolism and is essential for motor function and survival.
      Torres M, Lu Y, Pederson B, Wang H, Gretzinger A, Lin LL, Hwang J, Rupp A, Tomlinson A, Scott AJ, Zhao Z, Wahl DR, Myers M, Lyssiotis CA, Qi L. 2025 Jun 18; DOI:10.1101/2025.06.16.659938
      PMID: 40667142

    Featured News & Stories

    Research News

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    Medical School News

    2025 Dean’s Lecturer: GLP-1 therapies saving, improving lives of many patients

    Lives are being saved, and many others are being changed dramatically, by current GLP-1 therapies like tirzepatide, which has helped many patients treat type 2 diabetes and sleep apnea, and also lose weight. It has been a long road from bench research to clinical trials to the health care market, but patients are now benefitting more than ever, according to a leading scientist who served as the keynote speaker for the second annual Dean’s Lecture and Bold Science Symposium, “Metabolism Research from Bench to Bedside.” Daniel Skovronsky, M.D., Ph.D., chief scientific officer and executive vice president of science and technology at Eli Lilly and Company and president of Research Laboratories and Lilly Immunology, was the Dean’s Lecturer on April 14 at the North Campus Research Complex Dining Hall.