Mark E P Prince, MD, FRCS(C), FACS
Charles J Krause M.D. Collegiate Professor of Otolaryngology
Chair, Department of Otolaryngology-Head and Neck Surgery
Professor of Otolaryngology-Head and Neck Surgery
Service Chief, Otolaryngology Adult Service
Otolaryngology-Head and Neck Surgery
1500 East Medical Center Dr. - SPC 5312, 1904 Taubman Center
Ann Arbor, MI 48109
[email protected]

Available to mentor

Mark E P Prince, MD, FRCS(C), FACS
Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Dr. Mark Prince joined the Royal Canadian Navy after high school and completed a degree in chemical engineering at the Technical University of Nova Scotia. After earning his medical degree at Dalhousie University Medical School in Halifax, Nova Scotia, Prince went on to serve with the Canadian Armed Forces as a medical officer where he received specialized training in hyperbaric and diving medicine. Prince returned to Dalhousie University and completed a residency in otolaryngology-head and neck Surgery, followed by a two-year fellowship in advanced head and neck oncology and microvascular reconstructive surgery at the University of Michigan.

    In 1998, Prince accepted an appointment at Dalhousie as an assistant professor and served as their otolaryngology residency director before joining the University of Michigan faculty in 2000. He also served as the chief of the section of otolaryngology at the Ann Arbor VA Medical Center from 2000 until 2014; he continues to serve there as an active part time staff member.

    Most recently, Prince was appointed as the chair of the Department of Otolaryngology-Head and Neck Surgery after serving as the interim chair for almost 2 years. He is the author of over 160 scientific papers and several book chapters. His research laboratory published the first report of the identification of cancer stem cells in head and neck squamous cell cancer and continues to conduct research in this exciting field.

    Dr. Prince remains actively involved in resident and medical student education. He served as the department's residency program director until 2016 and as the associate chair for education from 2009-2016. He also served as the assistant dean for graduate medical education until 2018. He continues to co-lead a collaborative education initiative with the ENT department at Komfo Anokye Teaching Hospital in Kumasi, Ghana.

    Dr. Mark Prince cares for patients with a wide variety of otolaryngology problems. He has a special interest and advanced training in the treatment of patients with head and neck cancer and in reconstruction of complex defects in the head and neck including the mouth, jaw, pharynx, larynx and skull.

    Clinical
    Head and neck cancer, reconstructive surgery, thyroid cancer and nodules, salivary glands disease and cancer, swallowing disorder, and general otolaryngology.

    Qualifications
    • MD
      Dalhousie University Medical School, Halifax, 1988
    • Bachelor of Engineering, Chemical Engineering
      Technical University of Nova Scotia, Halifax, 1984
    • Diploma in Engineering
      Dalhousie University, Halifax, 1982
    Center Memberships
    • Center Member
      Global REACH
    Research Overview

    Cancer stem cells, cancer vaccines, and novel cancer therapies.

    Recent Publications See All Publications
    • Journal Article
      Comparison of Outcomes in Medical Therapy vs Surgical Intervention of Esophageal Foreign Bodies.
      Lin AY, Tillman BN, Thatcher AL, Graves CR, Prince ME. Otolaryngol Head Neck Surg, 2018 Oct; 159 (4): 656 - 661. DOI:10.1177/0194599818778277
      PMID: 29865972
    • Journal Article
      Comparison of Outcomes in Medical Therapy vs Surgical Intervention of Esophageal Foreign Bodies.
      Lin AY, Tillman BN, Thatcher AL, Graves CR, Prince ME. Otolaryngol Head Neck Surg, 2018 Oct; 159 (4): 656 - 661. DOI:10.1177/0194599818778277
      PMID: 29865972
    • Journal Article
      National trends in otolaryngology intern curricula following Accreditation Council for Graduate Medical Education changes.
      Kovatch KJ, Harvey RS, Prince MEP, Thorne MC. Laryngoscope, 2018 Aug; 128 (8): 1811 - 1816. DOI:10.1002/lary.26960
      PMID: 28990685
    • Journal Article
      The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
      Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Lui W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG, Cancer Genome Atlas Research Network , Spellman PT, Rathmell WK, Linehan WM. Cell Rep, 2018 Jun 19; 23 (12): 3698 DOI:10.1016/j.celrep.2018.06.032
      PMID: 29925010
    • Journal Article
      The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
      Ricketts CJ, De Cubas AA, Fan H, Smith CC, Lang M, Reznik E, Bowlby R, Gibb EA, Akbani R, Beroukhim R, Bottaro DP, Choueiri TK, Gibbs RA, Godwin AK, Haake S, Hakimi AA, Henske EP, Hsieh JJ, Ho TH, Kanchi RS, Krishnan B, Kwiatkowski DJ, Lui W, Merino MJ, Mills GB, Myers J, Nickerson ML, Reuter VE, Schmidt LS, Shelley CS, Shen H, Shuch B, Signoretti S, Srinivasan R, Tamboli P, Thomas G, Vincent BG, Vocke CD, Wheeler DA, Yang L, Kim WY, Robertson AG, Cancer Genome Atlas Research Network , Spellman PT, Rathmell WK, Linehan WM. Cell Rep, 2018 Jun 19; 23 (12): 3698 DOI:10.1016/j.celrep.2018.06.032
      PMID: 29925010
    • Journal Article
      Engineering Vaccines to Reprogram Immunity against Head and Neck Cancer.
      Tan YS, Sansanaphongpricha K, Prince MEP, Sun D, Wolf GT, Lei YL. J Dent Res, 2018 Jun; 97 (6): 627 - 634. DOI:10.1177/0022034518764416
      PMID: 29533731
    • Journal Article
      Engineering Vaccines to Reprogram Immunity against Head and Neck Cancer.
      Tan YS, Sansanaphongpricha K, Prince MEP, Sun D, Wolf GT, Lei YL. J Dent Res, 2018 Jun; 97 (6): 627 - 634. DOI:10.1177/0022034518764416
      PMID: 29533731
    • Journal Article
      Weighing Entrustment Decisions with Patient Care during Residency Training.
      Kovatch KJ, Prince MEP, Sandhu G. Otolaryngol Head Neck Surg, 2018 Jun; 158 (6): 1024 - 1027. DOI:10.1177/0194599818764652
      PMID: 29558240