John R Traynor
Edward F Domino Research Professor of Pharmacology
Professor of Pharmacology
Professor of Medicinal Chemistry
College of Pharmacy
[email protected]

Available to mentor
John R Traynor
Professor
  • Center Memberships
  • Links
  • Recent Publications
    • Center Memberships
    • Center Member
      Eisenberg Family Depression Center
    Links
    • Edward F. Domino Research Center
    • Traynor Lab
    Recent Publications See All Publications
    • Preprint
      The effects of chronic neuropathic pain on the self-administration of highly potent MOR agonist, fentanyl.
      Burgess GE, Traynor JR, Jutkiewicz EM. 2024 Nov 21; DOI:10.1101/2024.11.19.624389
      PMID: 39605379
    • Journal Article
      Correction to "Structure-Activity Relationships of the Fentanyl Scaffold: Identification of Antagonists as Potential Opioid Overdose Reversal Agents".
      Anand JP, Moore SC, Dixon EE, Perrien Naccarato CM, West JL, Delong LJ, Burgess E, Twarozynski JJ, Traynor JR. ACS Chem Neurosci, 2024 Oct 2; 15 (19): 3587 - 3588. DOI:10.1021/acschemneuro.4c00579
      PMID: 39354829
    • Preprint
      Xylazine Exacerbates Fentanyl-Induced Respiratory Depression and Bradycardia.
      Demery-Poulos C, Moore SC, Levitt ES, Anand JP, Traynor JR. 2024 Aug 19; DOI:10.1101/2024.08.16.608310
      PMID: 39229079
    • Journal Article
      Structure-Activity Relationships of the Fentanyl Scaffold: Identification of Antagonists as Potential Opioid Overdose Reversal Agents.
      Anand JP, Moore SC, Dixon EE, Perrien Naccarato CM, West JL, Delong LJ, Burgess E, Twarozynski JJ, Traynor JR. ACS Chem Neurosci, 2024 Aug 7; 15 (15): 2830 - 2841. DOI:10.1021/acschemneuro.4c00203
      PMID: 38994846
    • Journal Article
      Structure-Activity Relationships and Molecular Pharmacology of Positive Allosteric Modulators of the Mu-Opioid Receptor.
      Li M, Gan X, Liu K, Walajapet R, Stanczyk MA, Stewart HC, Rech JC, White AD, Traynor JR. ACS Chem Neurosci, 2025 Jan 1; 16 (1): 16 - 29. DOI:10.1021/acschemneuro.4c00541
      PMID: 39661492
    • Journal Article
      Application of Mixed-Solvent Molecular Dynamics Simulations for Prediction of Allosteric Sites on G Protein-Coupled Receptors.
      Chan WKB, Carlson HA, Traynor JR. Mol Pharmacol, 2023 May; 103 (5): 274 - 285. DOI:10.1124/molpharm.122.000612
      PMID: 36868791
    • Journal Article
      Opioid research in the time of the opioid crisis.
      Traynor JR, Moron JA. Br J Pharmacol, 2023 Apr; 180 (7): 793 - 796. DOI:10.1111/bph.16043
      PMID: 36813266
    • Journal Article
      Delta Opioid Receptor-Mediated Antidepressant-Like Effects of Diprenorphine in Mice.
      Olson KM, Hillhouse TM, Burgess GE, West JL, Hallahan JE, Dripps IJ, Ladetto AG, Rice KC, Jutkiewicz EM, Traynor JR. J Pharmacol Exp Ther, 2023 Mar; 384 (3): 343 - 352. DOI:10.1124/jpet.122.001182
      PMID: 36456196
    Featured News & Stories cell formation in grey and then two circles highlighed blue and one red
    Health Lab
    The solution to death from a fentanyl overdose could lie in its chemical structure
    University of Michigan researchers may have found that the solution to prevent people from dying from a fentanyl overdose may be found within fentanyl's own chemistry.
    Department News
    Congratulations to Dr. John Traynor
    Dr. John Traynor is one of 17 University of Michigan faculty members named 2022 AAAS Fellows.