Jack M Parent

 Jack M. Parent
William J Herdman Professor of Neurology
Professor of Neurology and Research Professor
Michigan Neuroscience Institute
Medical School
Email:
[email protected]
Available to mentor
Jack M Parent
Jack M. Parent
Professor
  • Qualifications
  • Center Memberships
  • Recent Publications

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    • Qualifications
    • Postdoctoral Fellow, Epilepsy Research Laboratory
      University of California, San Francisco, San Francisco, United States
      1996 - 2000
      Postdoctoral Fellowship
    • Fellow in Epilepsy and Clinical Neurophysiology, Department of Neurology
      University of California, San Francisco, San Francisco, United States
      1994 - 1996
      Postdoctoral Fellowship
    • Chief Resident, Department of Neurology
      University of California, San Francisco, San Francisco, United States
      1993 - 1994
      Chief Resident
    • Resident, Department of Neurology
      University of California, San Francisco, San Francisco, United States
      1991 - 1993
      Residency
    • Intern, Department of Internal Medicine
      University of California, San Francisco, San Francisco, United States
      1990 - 1991
      Internship
    • MD
      Yale University School of Medicine, New Haven, CT, United States
      1986 - 1990
    • AB
      Stanford University, Stanford, CA, United States
      1982 - 1986

    Center Memberships
    • Center Member
      Biosciences Initiative
    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Taubman Institute

    Recent Publications

     See All Publications
    • Journal Article
      Thalamic NRXN1-mediated input to human cortical progenitors drives excitatory neurogenesis.
      Nguyen CV, Martija A, Jaklic DC, White R, Yang MG, Nano PR, Soto JA, Mil J, Rana D, Martin JM, Schweiger HE, Hernandez S, Fazzari E, Liu Y, Parent JM, Mostajo-Radji MA, Geschwind DH, Bhaduri A. Science, 2026 Sep 3; 393 (6815): eady5180 DOI:10.1126/science.ady5180
      PMID: 42691176
    • Journal Article
      Navigating Human Astrocyte Differentiation: Direct and Rapid One-Step Differentiation of Induced Pluripotent Stem Cells to Functional Astrocytes Supporting Neuronal Network Development.
      Schuurmans IME, Mordelt A, Guevara-Ferrer M, Linda K, Duineveld D, Puvogel S, Hommersom MP, Scheefhals N, Rahm L, Dyke E, Scholten G-J, Knorz C, Jimenez CG, van Egmond N, Oudakker A, Bijnagte-Schoenmaker C, van Bokhoven H, Wei W, Hofmann S, Jung-Klawitter S, Mojica-Perez S, Parent J, Carotenuto L, Weckhuysen S, Maas N, Elgersma Y, van de Ven E, Lefeber D, Lygeroudi A, de Vries HE, Jordi L, Polymenidou M, Mitchell-Garcia T, Dragan I, Dolga A, de Witte LD, van Karnebeek CDM, Ellis J, Garanto A, Nadif Kasri N. Glia, 2026 Sep; 74 (9): e70202 DOI:10.1002/glia.70202
      PMID: PMC13370147
    • Journal Article
      People Powering Change: The Movement for a National Plan for Epilepsy
      Bender J, Dean B, Goodkin HP, Kapur J, Lado FA, Lowenstein DH, Mitchell A, Parent JM, Utley K, Weidner L. Epilepsy Currents, 2026 Aug 21; DOI:10.1177/15357597261469758
    • Preprint
      A CK2α–G3BP1 signaling axis regulates local translation in developing neurons and is disrupted in OCNDS
      Agrawal M, Desai M, Ghumra S, Bhorkar Y, Vaglio BJ, Stokes K, Rana K, Hamilton Hill N-Z, Nweze P, Sriram N, LoRé A, Kawaguchi R, Firestein BL, Parent J, Geschwind DH, Rebholz H, Sahoo PK. 2026 Aug 19; bioRxiv, DOI:10.64898/2026.08.11.744218
    • Journal Article
      Modeling Epilepsies with Human Brain Organoids: Recent Advances and Ongoing Challenges.
      Walker MP, Parent JM. Epilepsy Curr, 2026 Jul 28; 15357597261469411 DOI:10.1177/15357597261469411
      PMID: PMC13415638
    • Journal Article
      Cardiac remodeling and arrhythmia in a mouse model of Depdc5 haploinsufficiency
      Ramos-Mondragon R, Wang S, Liu Q, Chen C, Greiner AM, Marx AM, Shih M, Parent JM, London B, Isom LL. Epilepsia, 2026 Jan 1; DOI:10.1002/epi.70244
    • Journal Article
      Non-Synaptic Function and Localization of Syntaxin-Binding Protein 1 in a Mouse Model of STXBP1-Related Epileptic Encephalopathy
      Yang T, Banerjee R, Deng Y, Jahagirdar1 S, Nesvizhskii AI, Uhler MD, Parent JM, Wang Y. Annals of Neurology, 2026 Jan 1; DOI:10.1002/ana.78097
      PMID: 41510908
    • Preprint
      Hyperthermic Seizure Susceptibility and Focal Decreases in Parvalbumin-Expressing Cortical Interneurons in a Mouse Model of PCDH19-Clustering Epilepsy
      Ziobro J, Huang J, Daddo N, Margolis E, Jonatzke K, Umemori H, Parent JM. 2025 Nov 14; Cold Spring Harbor Laboratory, DOI:10.1101/2025.11.12.688097

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