George A Mashour

 portrait of George Mashour
Edward F Domino Collegiate Professor of Neuroscience
Vice Dean for Faculty
Professor of Anesthesiology
Program Director, Anesthesiology
Professor of Pharmacology
Medical School
[email protected]
Available to mentor
George A Mashour
portrait of George Mashour
VICE DEAN
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications

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    • Qualifications
    • MD, PhD
      Georgetown University, Washington D.C., United States

    Center Memberships
    • Center Member
      Weil Institute for Critical Care Research

    Research Overview

    Multidisciplinary approaches to the study of consciousness
    - Network mechanisms of consciousness and unconsciousness
    -Theories of consciousness
    - Interfaces of sleep neurobiology and general anesthesia
    - Intraoperative awareness and metrics of consciousness

    Recent Publications

     See All Publications
    • Journal Article
      An open fMRI resource for studying human brain function and covert consciousness under anesthesia
      Huang Z, Tarnal V, Fotiadis P, Vlisides PE, Janke EL, Puglia M, McKinney AM, Jang H, Dai R, Picton P, Mashour GA, Hudetz AG. Scientific Data, 2026 Dec 1; 13 (1): DOI:10.1038/s41597-025-06442-2
      PMID: 41513662
    • Journal Article
      Author Correction: Role of thalamus in human conscious perception revealed by low-intensity focused ultrasound neuromodulation (Nature Communications, (2025), 16, 1, (11700), 10.1038/s41467-025-66832-3)
      Jang H, Fotiadis P, Mashour GA, Hudetz AG, Huang Z. Nature Communications, 2026 Dec 1; 17 (1): DOI:10.1038/s41467-026-69395-z
      PMID: 41644954
    • Journal Article
      General Anesthesia and Discrete Components of Ketamine Neurophysiology.
      Deverett B, Li D, Lii TR, Vlisides PE, Tarnal V, Forsyth A, Sumner R, Sikka P, Schatzberg AF, Muthukumaraswamy S, Mashour GA, Heifets BD. JAMA Psychiatry, 2026 Apr 8; DOI:10.1001/jamapsychiatry.2026.0190
      PMID: PMC13063143
    • Preprint
      Opposing Network Patterns of Integration-Segregation in Psychedelic and Sedated States of Consciousness.
      Dai R, Jang H, Hudetz AG, Huang Z, Mashour GA. 2026 Feb 18; DOI:10.64898/2026.02.17.706398
      PMID: 41756858
    • Journal Article
      Neurochemical and Neurophysiological Effects of Intravenous Administration of N,N-Dimethyltryptamine in Rats
      Glynos NG, Huels ER, Groenhout T, Raghu A, Nelson A, Kim Y, Zeid AM, Liu T, Mashour GA, Kennedy RT, Pal D. Journal of Neuroscience the Official Journal of the Society for Neuroscience, 2026 Feb 4; 46 (5): DOI:10.1523/JNEUROSCI.0742-24.2025
      PMID: 41419333
    • Journal Article
      Minimum Alveolar Concentration Ratio Factors: Reply.
      Douville NJ, Kumar SS, Mashour GA. Anesthesiology, 2026 Jan 30; DOI:10.1097/ALN.0000000000005889
      PMID: 41619741
    • Preprint
      Acute effects of nitrous oxide on visual processing: a connectome study in healthy adults.
      Pouyan N, Kaplan C, Larkin T, Ichesco E, Eagan M, Preller K, Dunworth J, Harris R, Mashour G, Harte S. 2026 Feb 9; DOI:10.21203/rs.3.rs-8430361/v1
    • Chapter
      Chapter 3 Ketamine effects on brain dynamics
      Sleigh J, Mashour G. 2025 Oct 20; Ketamine, 37 - 55. DOI:10.1016/b978-0-443-29930-8.00003-5

    Featured News & Stories

         brain bright highlighter blue and lines on a monitor on each side
    Health Lab

    Brains and stock markets follow the same rules in crisis, study finds

    University of Michigan researchers reveal that the behaviors of brains and economies during crises can be explained using observations common in the realm of physics.
         George A. Mashour, M.D., Ph.D.
    Medical School News

    George A. Mashour, M.D., Ph.D., appointed interim executive vice dean for academic affairs/chief academic officer

    On Dec. 5, the Board of Regents approved the appointment of George A. Mashour, M.D., Ph.D., as interim executive vice dean for academic affairs (EVDAA) in the Medical School, effective January 1, 2025. He also will serve as interim chief academic officer (CAO) for Michigan Medicine. He takes over EVDAA/CAO duties from Debra F. Weinstein, M.D., who is leaving Michigan Medicine at the end of this year to become president and chief executive officer of the Accreditation Council for Graduate Medical Education
         brain drawn
    Health Lab

    The brain in balance

    In a recent study, using network neuroscience, investigators found a way to objectively determine the balance of integration and segregation in fMRI-measured brain signals during wakefulness as well as during sleep and anesthesia.
         88% Reduction in GHG Emissions
    Department News

    Green Anesthesia Initiative exceeds lofty goals for reduction in emissions

    The Department of Anesthesiology’s Green Anesthesia Initiative (GAIA) has taken an ambitious approach to environmental sustainability resulting in an 88% reduction of inhaled anesthetic greenhouse gas emissions.
    Department News

    George Mashour, MD, PhD, featured on the StarTalk Podcast

    George Mashour, MD, PhD at the University of Michigan Department of Anesthesiology featured on the StarTalk Podcast.
    Department News

    Green Anesthesia Initiative quickly shows progress

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