Janelle Pugashetti, MD

 profile-janelle-pugashetti-2022
Assistant Professor of Internal Medicine
Medical School
Available to mentor
Janelle Pugashetti, MD
profile-janelle-pugashetti-2022
Assistant Professor
  • About
  • Qualifications
  • Center Memberships
  • Recent Publications

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    • About

    Dr. Pugashetti is an Assistant Professor at the University of Michigan, in the Division of Pulmonary and Critical Care. After receiving her undergraduate degree from UCLA, she went on to receive her medical degree, Internal Medicine training, and fellowship in Pulmonary and Critical Care at UC Davis. Dr. Pugashetti has also completed a Master’s Degree in Epidemiology. She joined Michigan Medicine in 2022, where she now provides expert care for patients with interstitial lung disease (ILD) at the Taubman Pulmonary Clinic. She also staffs the Taubman Connective Tissue Disease-Associated ILD Clinic (CTD-ILD) where she works closely alongside Rheumatology colleagues. She leads the Interstitial Lung Disease program at the Ann Arbor VA.

    Dr. Pugashetti is interested in the intersection between autoimmune disease and lung disease. She is an emerging expert in CTD-ILD and is NIH-funded to study predictive biomarkers to guide therapeutic selection, thereby improving outcomes for patients with CTD-ILD.

    Qualifications
    • Fellowship
      University of California Davis, Pulmonary & Critical Care Medicine, Sacramento, United States
      2019 - 2022
    • Residency
      University of California Davis, Internal Medicine, Sacramento, United States
      2019 - 2019
    • M.S., Epidemiology
      University of California Davis, Sacramento, United States
      2021 - 2022
    • M.D.
      University of California Davis, Sacramento, United States
      2012 - 2016
    • B.S., Psychobiology
      University of California, Los Angeles, Los Angeles, CA, United States
      2007 - 2011

    Center Memberships
    • Center Member
      AI and Digital Health Innovation

    Recent Publications

     See All Publications
    • Journal Article
      Sex-related transcriptomic differences in idiopathic pulmonary fibrosis.
      Menon AA, Moll M, Pugashetti JV, Linderholm AL, Liu GY, Krishna R, Noth I, Hunninghake GM, Feghali-Bostwick C, Ghosh AJ. Am J Respir Crit Care Med, 2026 Feb 21; DOI:10.1093/ajrccm/aamag080
      PMID: 41738237
    • Journal Article
      Prioritizing Therapeutic Targets for Interstitial Lung Disease: A Causal Mediation Analysis.
      Oldham J, Molyneaux P, Maddali M, Newton C, Kim J, Konkol S, Pugashetti J, Liu G, Goobie G, Adegunsoye A, Ma S-F, Bornstein D, Murray S, Wain L, Saini G, Stewart I, Johnson S, Jenkins G, Strek M, Linderholm A, Chen C-H, Fahy W, Zemans R, Moore B, Khanna D, Ryerson C, Flaherty K, Suresh M, Hoffmann-Vold A-M, Maher T, Garcia C, Wolters P, Martinez F, Noth I, Smith JA. Res Sq, 2026 Feb 5; DOI:10.21203/rs.3.rs-8714555/v1
      PMID: PMC12889817
    • Journal Article
      Molecular endotypes predict differential response to immunosuppressant therapy in non-IPF interstitial lung disease
      Maddali MV, Pugashetti JV, Pienkos SM, Moore AR, Konkol SB, Kim JS, Ma S-F, Newton CA, Garcia CK, Adegunsoye A, Strek ME, Chen C-H, Linderholm AL, Zemans RL, Moore BB, Wolters PJ, Raj R, Chen JH, Martinez FJ, Noth I, Rogers AJ, Oldham JM. American Journal of Respiratory and Critical Care Medicine, 2026 Feb 1; DOI:10.1093/ajrccm/aamag006
    • Proceeding / Abstract / Poster
      A CT imaging measure of combined pulmonary fibrosis and emphysema (CPFE)
      Wang J, Pugashetti J, Murray S, Mohan N, Nazemi N, Kang E, Kazerooni E, Flaherty K, Belloli E, Sheth J, O'Dwyer D, Hatt C, Han M, Oldham J. 2025 Dec 1; pa2971 DOI:10.1183/13993003.congress-2025.pa2971
    • Journal Article
      Associations of High Attenuation Area-related Proteomic Biomarkers with Fibrotic or Subpleural Interstitial Lung Abnormalities.
      Kim JS, Debban CL, Guzman D, Hannan RT, Salvatore M, McGroder C, Zhang D, Podolanczuk AJ, Duprez DA, Ma S-F, Huang Y, Sturek JM, Rich SS, Rotter JI, Deo R, Dubin RF, Pugashetti JV, Wang JM, Han MK, Oldham JM, Noth I, Woodruff PG, Ortega VE, Fanburg-Smith JC, Stelow EB, Moskaluk CA, Hoffman EA, Garcia CK, Bowler RP, Ganz P, Barr RG, Manichaikul A. Am J Respir Crit Care Med, 2025 Aug 22; DOI:10.1164/rccm.202503-0610OC
      PMID: 40845333
    • Journal Article
      A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis.
      Wang JM, Adegunsoye A, Pugashetti JV, Lee CT, Murray S, Mohan N, Nazemi N, Kang E, Chelala L, Kazerooni EA, Flaherty KR, Belloli EA, Sheth JS, O'Dwyer DN, Strek ME, Hatt CR, Han MK, Chung JH, Oldham JM. Am J Respir Crit Care Med, 2025 Jul 18; DOI:10.1164/rccm.202501-0208OC
      PMID: 40680162
    • Proceeding / Abstract / Poster
      A Quantitative Imaging Measure of Progressive Pulmonary Fibrosis
      Wang JM, Adegunsoye AO, Pugashetti JV, Lee CT, Murray S, Mohan N, Nazemi N, Kang E, Chelala L, Kazerooni E, Flaherty KR, Belloli E, Sheth JSV, O'Dwyer DN, Strek ME, Hatt CR, Han MK, Chung JH, Oldham J. American Journal of Respiratory and Critical Care Medicine, 2025 May 15; 211 (Abstracts): a7682 - a7682. DOI:10.1164/ajrccm.2025.211.abstracts.a7682
    • Proceeding / Abstract / Poster
      Molecular Endotypes Predict Differential Response to Immunosuppression in Non-IPF Interstitial Lung Disease
      Maddali MV, Pienkos S, Moore AR, Konkol SB, Kim J, Ma SF, Newton C, Garcia CK, Adegunsoye AO, Strek ME, Chen C-H, Linderholm A, Zemans RL, Moore BB, Wolters PJ, Raj R, Chen JH, Martinez FJ, Noth I, Rogers A, Oldham J, Pugashetti JV. American Journal of Respiratory and Critical Care Medicine, 2025 May 15; 211 (Abstracts): a2854 - a2854. DOI:10.1164/ajrccm.2025.211.abstracts.a2854