Research Investigator
Ophthalmology and Visual Science
[email protected]
Available to mentor
Eric Weh
Research Investigator
-
Subramanya S, Fernando R, Goswami M, Besirli CG, Weh E, Wubben TJ. Exp Eye Res, 2023 Aug; 233: 109563Journal ArticleFlow cytometric method for the detection and quantification of retinal cell death and oxidative stress.
DOI:10.1016/j.exer.2023.109563 PMID: 37393050 -
Weh E, Goswami M, Chaudhury S, Fernando R, Miller N, Hager H, Sheskey S, Sharma V, Wubben TJ, Besirli CG. Cells, 2023 Aug 10; 12 (16):Journal ArticleMetabolic Alterations Caused by Simultaneous Loss of HK2 and PKM2 Leads to Photoreceptor Dysfunction and Degeneration.
DOI:10.3390/cells12162043 PMID: 37626853 -
Wubben TJ, Chaudhury S, Watch BT, Stuckey JA, Weh E, Fernando R, Goswami M, Pawar M, Rech JC, Besirli CG. Pharmaceuticals (Basel), 2023 May 6; 16 (5):Journal ArticleDevelopment of Novel Small-Molecule Activators of Pyruvate Kinase Muscle Isozyme 2, PKM2, to Reduce Photoreceptor Apoptosis.
DOI:10.3390/ph16050705 PMID: 37242488 -
Subramanya S, Goswami MT, Miller N, Weh E, Chaudhury S, Zhang L, Andren A, Hager H, Weh KM, Lyssiotis CA, Besirli CG, Wubben TJ. Frontiers in Ophthalmology, 2023 Jan 1; 3:Journal ArticleRod photoreceptor-specific deletion of cytosolic aspartate aminotransferase, GOT1, causes retinal degeneration
DOI:10.3389/fopht.2023.1306019 -
Weh E, Scott K, Wubben TJ, Besirli CG. Exp Eye Res, 2022 Feb; 215: 108913Journal ArticleDark-reared rd10 mice experience rapid photoreceptor degeneration with short exposure to room-light during in vivo retinal imaging.
DOI:10.1016/j.exer.2021.108913 PMID: 34965404 -
Mei L, Yu M, Liu Y, Weh E, Pawar M, Li L, Besirli CG, Schwendeman AA. Nanomedicine, 2022 Aug; 44: 102571Journal ArticleSynthetic high-density lipoprotein nanoparticles delivering rapamycin for the treatment of age-related macular degeneration.
DOI:10.1016/j.nano.2022.102571 PMID: 35623563 -
Wubben TJ, Pawar M, Weh E, Smith A, Sajjakulnukit P, Zhang L, Dai L, Hager H, Pai MP, Lyssiotis CA, Besirli CG. Sci Rep, 2020 Feb 19; 10 (1): 2990Journal ArticleSmall molecule activation of metabolic enzyme pyruvate kinase muscle isozyme 2, PKM2, circumvents photoreceptor apoptosis.
DOI:10.1038/s41598-020-59999-w PMID: 32076076 -
Weh E, Lutrzykowska Z, Smith A, Hager H, Pawar M, Wubben TJ, Besirli CG. Cell Death Dis, 2020 Jun 4; 11 (6): 422Journal ArticleHexokinase 2 is dispensable for photoreceptor development but is required for survival during aging and outer retinal stress.
DOI:10.1038/s41419-020-2638-2 PMID: 32499533
