Longhua Guo, PhD
Assistant Professor of Molecular and Integrative Physiology
Assistant Professor of Cell and Developmental Biology
Research Assistant Professor
Institute of Gerontology
[email protected]

Available to mentor
Longhua Guo, PhD
Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • Qualifications
    • Postdoc
      University of California, Los Angeles, Human Genetics, 2022
    • Postdoc
      Stowers Institute for Medical Research, Kansas City, 2017
    • PhD
      University of Utah, Salt Lake City, 2016
    Center Memberships
    • Center Member
      Center for Cell Plasticity and Organ Design
    Research Overview

    Genetics, Aging, Regeneration, Age reversal, Rejuvenation

    Recent Publications See All Publications
    • Journal Article
      Oogenesis involves a novel nuclear envelop remodeling mechanism in Schmidtea mediterranea.
      Guo L, Guo F, Zhang S, Zeng A, Yi K, McClain M, Kuhn C-D, Parmely T, Alvarado AS. Dev Biol, 2024 Dec 26; 520: 13 - 20. DOI:10.1016/j.ydbio.2024.12.018
      PMID: 39732384
    • Journal Article
      Extraordinary model systems for regeneration.
      Accorsi A, Guo L, Marshall WF, Mommersteeg MTM, Nakajima Y-I. Development, 2024 Oct 15; 151 (20): DOI:10.1242/dev.203083
      PMID: 39012059
    • Journal Article
      Developmental defects in planarian hatchlings (Platyhelminthes: Rhabditophora)
      Dai X, Sobota J, Li X, Guo L. Zoologia, 2024 Jan 1; 41: DOI:10.1590/S1984-4689.v41.e23087
    • Journal Article
      Genetics and biology of coloration in reptiles: the curious case of the Lemon Frost geckos.
      Guo L, Kruglyak L. Physiol Genomics, 2023 Nov 1; 55 (11): 479 - 486. DOI:10.1152/physiolgenomics.00015.2023
      PMID: 37642275
    • Preprint
      Regeneration leads to global tissue rejuvenation in aging sexual planarians
      Dai X, Li X, Pletcher S, Paris D, Kruglyak L, Sobota J, Guo L. 2023 bioRxiv, DOI:10.1101/2023.06.24.546358
    • Journal Article
      Genomic epidemiology of the Los Angeles COVID-19 outbreak and the early history of the B.1.43 strain in the USA.
      Guo L, Boocock J, Hilt EE, Chandrasekaran S, Zhang Y, Munugala C, Sathe L, Alexander N, Arboleda VA, Flint J, Eskin E, Luo C, Yang S, Garner OB, Yin Y, Bloom JS, Kruglyak L. BMC Genomics, 2022 Apr 4; 23 (1): 260 DOI:10.1186/s12864-022-08488-7
      PMID: 35379194
    • Journal Article
      Molecular characterization of a flatworm Girardia isolate from Guanajuato, Mexico.
      Duncan EM, Nowotarski SH, Guerrero-Hernández C, Ross EJ, D'Orazio JA, Clubes de Ciencia México Workshop for Developmental Biology , McKinney S, McHargue MC, Guo L, McClain M, Alvarado AS. Dev Biol, 2022 Sep; 489: 165 - 177. DOI:10.1016/j.ydbio.2022.06.003
      PMID: 35710033
    • Journal Article
      Island-specific evolution of a sex-primed autosome in a sexual planarian.
      Guo L, Bloom JS, Dols-Serrate D, Boocock J, Ben-David E, Schubert OT, Kozuma K, Ho K, Warda E, Chui C, Wei Y, Leighton D, Lemus Vergara T, Riutort M, Sánchez Alvarado A, Kruglyak L. Nature, 2022 Jun; 606 (7913): 329 - 334. DOI:10.1038/s41586-022-04757-3
      PMID: 35650439
    Featured News & Stories
    Department News
    CDB is excited to welcome Longhua Guo, PhD!
    Longhua's research focuses on aging, regeneration, and global rejuvenation, using planarians (Schmidtea mediterranea) and leopard geckos (Eublepharis macularius). The Guo lab applies a variety of techniques in genetics, genomics, molecular, cellular, and developmental biology.
    News Release
    NIH High-Risk, High-Reward program awards three U-M Medical School investigators
    Three U-M investigators—Changyang Linghu, Longhua Guo and Sundeep Kalantry—have been acknowledged by the National Institutes of Health’s (NIH) prestigious High-Risk, High-Reward Research program.
    Department News
    Dr. Longhua Guo named a 2024 Pew Scholar
    Congrats to Dr. Longhua Guo for being named a 2024 Pew Scholar to support his research on the molecular and cellular processes that reverse tissue aging.