Eileen S Carpenter, MD, PhD
1500 East Medical Center Drive
Ann Arbor, Michigan 48109
Manage Your Profile
About
Eileen received her undergraduate chemical engineering degree from the Cooper Union and her combined MD/PhD from SUNY Stony Brook University through the Medical Scientist Training Program. She then joined the University of Michigan and completed her internal medicine residency and gastroenterology fellowship through their fast-track research pathway. She recently joined faculty at the University of Michigan and has an appointment at the University of Michigan affiliate, VA Ann Arbor Healthcare System. Her clinical practice is focused on treating patients with benign and malignant diseases of the pancreas. In her free time, she enjoys taking care of her three kids, playing the piano, volunteering at church, /and serving on the local Little League board.
Qualifications
-
FellowshipUniversity of Michigan, Internal Medicine, Gastroenterology, Ann Arbor, United States
2017 - 2020
Clinical Fellowship
-
ResidencyUniversity of Michigan, Internal Medicine, Ann Arbor, Michigan, United States
2015 - 2017
Residency
Center Memberships
-
Center MemberRogel Cancer Center
Research Overview
Dr. Carpenter’s recent research accomplishments include establishing a pipeline using endoscopic fine needle biopsies of pancreatic tumors for a wide variety of techniques, including single-cell RNA sequencing, mass cytometry, and organoid culture. The Carpenter lab is currently focused on extending existing pipelines to study chemoresistance using longitudinal matched samples in patients pre- and post-chemotherapy, with the goal of identifying new immunotherapeutic targets to overcome chemo-refractory disease in pancreatic ductal adenocarcinoma.
Recent Publications
-
Zhang Y, Kadiyala P, Yan W, Brown K, Avritt FR, Donahue KL, Procario MC, Okoye JO, Giridharan T, Elhossiny AM, Espinoza CE, Awad D, Lasse Opsahl EL, Medina-Cabrera PI, Velez-Delgado A, Menjivar RE, Yang OA, Yang S, He X, Gupta S, Tariq R, Brandt AR, Wang X, denDekker A, Nwosu ZC, Carpenter ES, Courtney AH, Bednar F, Frankel TL, Lyssiotis CA, Zheng B, Kryczek I, Pasca di Magliano M. Cancer Immunol Res, 2026 May 28;Journal ArticleTargeting CCR1 remodels the tumor microenvironment and relieves immune suppression in pancreatic cancer.
DOI:10.1158/2326-6066.CIR-25-1300 PMID: 42207977 -
Elhossiny AM, Kadiyala P, Okoye JO, Hiraki HL, Procario MC, Giridharan T, Watkoske HR, Tannus Ruckert M, Wang J, Griffith BD, Bray AW, Mills JN, Espinoza CE, Zeller J, Peterson N, Bednar F, Zhang Y, Rao A, Lyssiotis CA, Szczepanski JM, Shi J, Deshpande A, Maitra A, Fertig EJ, Carpenter ES, Frankel TL, Pasca di Magliano M. Cancer Discov, 2026 May 21;Journal ArticleAsynchronous evolution of epithelium and stroma differentiates precursor lesions from pancreatic cancer.
DOI:10.1158/2159-8290.CD-25-2001 PMID: 42165710 -
Henstridge A, Sahai V, Peterson N, Machicado JD, Kwon R, Schulman AR, Wamsteker E-J, Philips GM, Menees SB, Xia JY, Hogenson T, Shi J, Frankel T, Bednar F, Di Magliano MP, Lyssiotis CA, Truty MJ, Fernandez-Zapico ME, Carpenter E. Gastrointestinal Endoscopy, 2026 May 3; 103 (5): s - 2850.Journal Article296b LONGITUDINAL ANALYSIS OF MATCHED PATIENT BIOSPECIMENS REVEALS NEURAL REPROGRAMMING OF CANCER-ASSOCIATED FIBROBLASTS FOLLOWING CHEMOTHERAPY IN PANCREATIC DUCTAL ADENOCARCINOMA
DOI:10.1016/s0016-5107(26)06672-1 -
Henstridge A, Sahai V, Peterson N, Machicado JD, Kwon R, Schulman AR, Wamsteker E-J, Philips GM, Menees SB, Xia JY, Hogenson T, Shi J, Frankel T, Bednar F, Di Magliano MP, Lyssiotis CA, Truty MJ, Fernandez-Zapico ME, Carpenter E. Gastroenterology, 2026 May 7; 170 (6): s - 2850.Journal Article296b LONGITUDINAL ANALYSIS OF MATCHED PATIENT BIOSPECIMENS REVEALS NEURAL REPROGRAMMING OF CANCER-ASSOCIATED FIBROBLASTS FOLLOWING CHEMOTHERAPY IN PANCREATIC DUCTAL ADENOCARCINOMA
DOI:10.1016/s0016-5085(26)06741-7 -
Carpenter E. 2026 Apr 27;PresentationDeveloping an All-Human Preclinical Model of Perineural Invasion
-
Singhal R, Zhang NW, Lee ZH, Bell HN, Dalal PJ, Solanki S, Huang W, Rebernick R, Sajjakulnukit P, Jasewicz H, Kumar R, Kotla NK, Huber A, Mallappa AV, Arya SB, Takahashi S, Kasano-Camones CI, Carpenter E, di Magliano MP, Moon JJ, Parent CA, Gonzalez FJ, Patterson AD, Green MD, Zou W, Stoffel EM, Lyssiotis CA, Shah YM. 2026 Apr 8; bioRxiv,PreprintFatty acids in the tumor microenvironment reprogram neutrophils to induce immunosuppression via adenosine
DOI:10.64898/2026.04.02.716169 -
Li J, Branch G, Macchia J, Elhossiny AM, Arya N, Liang J, Kadiyala P, Peterson N, Kwon R, Machicado JD, Wamsteker E-J, Schulman A, Philips G, Menees S, Xia J, Singhi AD, Sahai V, Fang JM, Frankel TL, Bednar F, Pasca di Magliano M, Shi J, Carpenter ES. Cell Mol Gastroenterol Hepatol, 2026 Feb 2; 101749Journal ArticleSpatial analysis of IPMNs defines a paradoxical KRT17-positive, low-grade epithelial population harboring malignant features.
DOI:10.1016/j.jcmgh.2026.101749 PMID: 41638478 -
Griffith BD, Kadiyala P, McGue J, Sun L, Kumar A, Espinoza CE, Donahue KL, Iyer MK, Speyer C, Nelson S, Spiteri A, Elhossiny AM, Brown K, Attebury H, Bednar F, Carpenter ES, Kryczek I, Zhang Y, Zou W, Pasca di Magliano M, Frankel TL. 2026 Jan 12;Additional ScholarshipData from Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization
DOI:10.1158/2159-8290.c.8239507
Featured News & Stories
Tackling Pancreatic Cancer, Bench to Bedside
New Publication by Carpenter, ElHossiny and Kadiyala (Pasca di Magliano Lab)
