Ann Arbor
Michigan, 48109 United States
Available to mentor
Eileen received her undergraduate chemical engineering degree from the Cooper Union and her combined MD/PhD from SUNY Stony Brook University through the Medical Scientist Training Program. She then joined the University of Michigan and completed her internal medicine residency and gastroenterology fellowship through their fast-track research pathway. She recently joined faculty at the University of Michigan and has an appointment at the University of Michigan affiliate, VA Ann Arbor Healthcare System. Her clinical practice is focused on treating patients with benign and malignant diseases of the pancreas. In her free time, she enjoys taking care of her three kids, playing the piano, volunteering at church, /and serving on the local Little League board.
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FellowshipUniversity of Michigan, Internal Medicine, Gastroenterology, 2020
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ResidencyUniversity of Michigan, Internal Medicine, 2017
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Center MemberRogel Cancer Center
Dr. Carpenter’s recent research accomplishments include establishing a pipeline using endoscopic fine needle biopsies of pancreatic tumors for a wide variety of techniques, including single-cell RNA sequencing, mass cytometry, and organoid culture. The Carpenter lab is currently focused on extending existing pipelines to study chemoresistance using longitudinal matched samples in patients pre- and post-chemotherapy, with the goal of identifying new immunotherapeutic targets to overcome chemo-refractory disease in pancreatic ductal adenocarcinoma.
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Vargas A, Dutta P, Carpenter ES, Machicado JD. Diagnostics (Basel), 2024 Mar 6; 14 (5):Journal ArticleEndoscopic Ultrasound-Guided Ablation of Premalignant Pancreatic Cysts and Pancreatic Cancer.
DOI:10.3390/diagnostics14050564 PMID: 38473035 -
Mills JN, Thompson J, Morales J, Kadiyala P, Elhossiny AM, Crawford H, Carpenter E, di Magliano MP, Bednar F, Benitz S. Cancer Research, 2024 Jan 16; 84 (2_Supplement): b113 - b113.Journal ArticleAbstract B113: Characterization of the epigenomic landscape of the human pancreas and early pancreatic neoplastic lesions
DOI:10.1158/1538-7445.panca2023-b113 -
Yan W, Menjivar RE, Bonilla ME, Steele NG, Kemp SB, Du W, Donahue KL, Brown KL, Carpenter ES, Avritt FR, Irizarry-Negron VM, Yang S, Burns WR, Zhang Y, Pasca di Magliano M, Bednar F. Cancer Immunol Res, 2024 Jan 3; 12 (1): 91 - 106.Journal ArticleNotch Signaling Regulates Immunosuppressive Tumor-Associated Macrophage Function in Pancreatic Cancer.
DOI:10.1158/2326-6066.CIR-23-0037 PMID: 37931247 -
Mello AM, Ngodup T, Lee Y, Donahue KL, Li J, Rao A, Carpenter ES, Crawford HC, Magliano MPD, Lee KE. Cancer Immunology Research, 2023 Dec 1; 11 (12_Supplement): pr03 - pr03.Journal ArticleAbstract PR03: Hypoxia promotes inflammatory fibroblast formation in pancreatic cancer
DOI:10.1158/2326-6074.tumimm23-pr03 -
Carpenter ES, Kadiyala P, Elhossiny AM, Kemp SB, Li J, Steele NG, Nicolle R, Nwosu ZC, Freeman J, Dai H, Paglia D, Du W, Donahue K, Morales J, Medina-Cabrera PI, Bonilla ME, Harris L, The S, Gunchick V, Peterson N, Brown K, Mattea M, Espinoza CE, McGue J, Kabala SM, Baliira RK, Renollet NM, Mooney AG, Liu J, Bhalla S, Farida JP, Ko C, Machicado JD, Kwon RS, Wamsteker E-J, Schulman A, Anderson MA, Law R, Prabhu A, Coulombe PA, Rao A, Frankel TL, Bednar F, Shi J, Sahai V, Pasca di Magliano M. Clin Cancer Res, 2023 Oct 18;Journal ArticleKRT17High/CXCL8+ tumor cells display both classical and basal features and regulate myeloid infiltration in the pancreatic cancer microenvironment.
DOI:10.1158/1078-0432.CCR-23-1421 PMID: 37851080 -
Carpenter ES, Elhossiny AM, Kadiyala P, Li J, McGue J, Griffith BD, Zhang Y, Edwards J, Nelson S, Lima F, Donahue KL, Du W, Bischoff AC, Alomari D, Watkoske HR, Mattea M, The S, Espinoza CE, Barrett M, Sonnenday CJ, Olden N, Chen C-T, Peterson N, Gunchick V, Sahai V, Rao A, Bednar F, Shi J, Frankel TL, Pasca di Magliano M. Cancer Discov, 2023 Jun 2; 13 (6): 1324 - 1345.Journal ArticleAnalysis of Donor Pancreata Defines the Transcriptomic Signature and Microenvironment of Early Neoplastic Lesions.
DOI:10.1158/2159-8290.CD-23-0013 PMID: 37021392 -
Nwosu ZC, Ward MH, Sajjakulnukit P, Poudel P, Ragulan C, Kasperek S, Radyk M, Sutton D, Menjivar RE, Andren A, Apiz-Saab JJ, Tolstyka Z, Brown K, Lee H-J, Dzierozynski LN, He X, Ps H, Ugras J, Nyamundanda G, Zhang L, Halbrook CJ, Carpenter ES, Shi J, Shriver LP, Patti GJ, Muir A, Pasca di Magliano M, Sadanandam A, Lyssiotis CA. Nature, 2023 Jun; 618 (7963): 151 - 158.Journal ArticleUridine-derived ribose fuels glucose-restricted pancreatic cancer.
DOI:10.1038/s41586-023-06073-w PMID: 37198494 -
Li J, Macchia J, Elhossiny A, Peterson N, Gunchick V, Mattea M, Kwon R, Machicado J, Wamsteker E-J, Schulman AR, Philips GM, Shi J, Sahai V, Carpenter E. Gastroenterology, 2023 May; 164 (6): s-770-s-771Proceeding / Abstract / PosterMo1137 SPATIAL TRANSCRIPTOMIC ANALYSIS OF INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS IDENTIFIES POTENTIAL BIOMARKERS OF GRADE OF DYSPLASIA
DOI:10.1016/s0016-5085(23)02779-8
