David Ginsburg
James V Neel Distinguished University Professor of Internal Medicine and Human Genetics
Warner-Lambert/Parke-Davis Professor of Medicine
Professor of Internal Medicine
Professor of Human Genetics
Professor of Pediatrics
Medical School and Research Professor
Life Sciences Institute
[email protected]
Available to mentor
David Ginsburg
Research Professor
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Center Memberships
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberTaubman Institute
Recent Publications
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Chen X-W, Wang H, Bajaj K, Zhang P, Ma D, Bai Y, Liu H-H, Adams E, Baines A, Yu G, Sartor MA, Zhang B, Yi Z, Lin J, Young SG, Schekman R, Ginsburg D. Elife, 2026 Jun 24; 15:Journal ArticleCorrection: SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion.
DOI:10.7554/eLife.112375 PMID: 42339786 -
Thompson AD, Pankiewicz C, Plenge LS, Lilienthal U, Kotaru S, Vignesh M, Phan T, McAllister C, Yob J, Ingles J, Hespe S, Helms AS, Ginsburg D, Day SM, SHaRe consortium investigators . 2026 Jun 11;PreprintPathogenic MYBPC3 missense variants alter protein-protein interactions within the sarcomere.
DOI:10.64898/2026.05.27.727676 PMID: 42327163 -
Smith AN, Beg MA, Hur WS, Ginsburg D, Kullo IJ, Davies SS, Tabas I, Williams JW, Mineo C, Cai B, Gupta RK, Amengual J, Schwendeman A, Graf GA, Sorci Thomas M, Zheng Z. J Lipid Res, 2026 Apr 16; 101041Journal ArticleFrom Lipoprotein Metabolism to Blood Clotting: Highlights of the 2025 Fredrickson Lipid Research Conference.
DOI:10.1016/j.jlr.2026.101041 PMID: 41999980 -
Holding ML, Pontius MHH, Ward MS, Akhtar J, Crowell HL, Svilar D, Keeler KM, Haynes LM, Ginsburg D, Shavit JA. Evolution, 2026 Mar 11;Journal ArticleDeconstructing cardiovascular and coagulation-related traits links dietary ecology to multi-functional snake venom specificity.
DOI:10.1093/evolut/qpag036 PMID: 41811938 -
Baid S, Holding ML, Laurin T, Seimeiniak D, Ginsburg D, Haynes LM. 2026 Feb 4;PreprintMapping the Mutational Landscape for Streptokinase Binding to Plasminogen.
DOI:10.64898/2026.02.04.703780 PMID: 41684937 -
Verma R, Cleuren A, Hinkovska-Galcheva V, Decker I, Kelly R, Ginsburg D, Shayman JA. Kidney International, 2026 Jan 1;Journal ArticleHeat shock protein 70s are modifiers of endothelial function in Fabry disease
DOI:10.1016/j.kint.2026.01.004 PMID: 41579958 -
Haynes LM, Holding ML, Woodard J, Siemieniak D, Ginsburg D. Journal of Biological Chemistry, 2025 Dec 1; 301 (12):Journal ArticleThermodynamics and selection of the plasminogen activator inhibitor-1 latency transition
DOI:10.1016/j.jbc.2025.110896 PMID: 41197721 -
Novakovic V, Kretz C, Stalker T, Cleuren A, Ginsburg D, Gilbert G. Blood, 2025 Dec 8; 146 (Supplement 1): 4836Journal ArticlePhosphatidylserine-rich platelet blebs enhance hemostasis after mucous membrane injury but not after skin or vascular injury: Studies with ANO6-deficient mice
DOI:10.1182/blood-2025-4836
Featured News & Stories
Department News
Highlighted Publications: January - May 2026
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Highlighted Publications: August - December 2025
Department of Human Genetics faculty are involved in widely diverse areas of research, from Genome Structure and Function research to Evolutionary and Population Genetics.
Department News
Life-changing Therapeutics
The U.S. Food and Drug Administration recently approved the first available therapeutic treatment for a rare, life-threatening genetic disorder.
