James V Neel Distinguished University Professor of Internal Medicine and Human Genetics
Warner-Lambert/Parke-Davis Professor of Medicine
Professor of Internal Medicine
Professor of Human Genetics
Professor of Pediatrics
Research Professor
Life Sciences Institute
[email protected]
Available to mentor
David Ginsburg
Research Professor
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Center MemberCenter for Cell Plasticity and Organ Design
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Center MemberTaubman Institute
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Haynes LM, Holding ML, DiGiovanni H, Siemieniak D, Ginsburg D. 2024 Sep 20;PreprintHigh-throughput amino acid-level characterization of the interactions of plasminogen activator inhibitor-1 with variably divergent proteases.
DOI:10.1101/2024.09.16.612699 PMID: 39345533 -
Tang VT, Xiang J, Chen Z, McCormick J, Abbineni PS, Chen X-W, Hoenerhoff M, Emmer BT, Khoriaty R, Lin JD, Ginsburg D. Proc Natl Acad Sci U S A, 2024 May 7; 121 (19): e2322164121Journal ArticleFunctional overlap between the mammalian Sar1a and Sar1b paralogs in vivo.
DOI:10.1073/pnas.2322164121 PMID: 38687799 -
Tang VT, Xiang J, Chen Z, McCormick J, Abbineni PS, Chen X-W, Hoenerhoff M, Emmer BT, Khoriaty R, Lin JD, Ginsburg D. 2024 Feb 29;PreprintFunctional overlap between the mammalian Sar1a and Sar1b paralogs in vivo.
DOI:10.1101/2024.02.27.582310 PMID: 38463989 -
Tang VT, Abbineni PS, Veiga Leprevost FD, Basrur V, Khoriaty R, Emmer BT, Nesvizhskii AI, Ginsburg D. J Proteome Res, 2023 Nov 3; 22 (11): 3439 - 3446.Journal ArticleIdentification of LMAN1- and SURF4-Dependent Secretory Cargoes.
DOI:10.1021/acs.jproteome.3c00259 PMID: 37844105 -
Thompson AD, Wagner MJ, Rodriguez J, Malhotra A, Vander Roest S, Lilienthal U, Shao H, Vignesh M, Weber K, Yob JM, Prosser BL, Helms AS, Gestwicki JE, Ginsburg D, Day SM. JACC Basic Transl Sci, 2023 Sep; 8 (9): 1198 - 1211.Journal ArticleAn Unbiased Screen Identified the Hsp70-BAG3 Complex as a Regulator of Myosin-Binding Protein C3.
DOI:10.1016/j.jacbts.2023.04.009 PMID: 37791314 -
Haynes LM, Holding ML, Trost E, DiGiovanni H, Siemieniak D, Ginsburg D. Arteriosclerosis Thrombosis and Vascular Biology, 2023 May; 43 (Suppl_1):Journal ArticleAbstract 133: Engineering Plasminogen Activator Inhibitor-1 Variants With Novel Protease Inhibitor Activity
DOI:10.1161/atvb.43.suppl_1.133 -
Tang VT, Abbineni PS, Leprevost FDV, Basrur V, Emmer BT, Nesvizhskii AI, Ginsburg D. 2023 Apr 6;PreprintIdentification of LMAN1 and SURF4 dependent secretory cargoes.
DOI:10.1101/2023.04.06.535922 PMID: 37066360 -
Abbineni PS, Tang V, Ginsburg D. Biophysical Journal, 2023 Feb; 122 (3): 516aJournal ArticleDissecting molecular regulation of unconventional protein secretion
DOI:10.1016/j.bpj.2022.11.2747
Department News
The U.S. Food and Drug Administration recently approved the first available therapeutic treatment for a rare, life-threatening genetic disorder.
