Melissa A Elafros, MD, PhD

Melissa Elafros, MD, PhD
Assistant Professor
Available to mentor
Melissa A Elafros, MD, PhD
Melissa Elafros, MD, PhD
Assistant Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Dr. Elafros is the Andrea and Lawrence A. Wolfe Research Professor in the Department of Neurology. With a focus on improving access to quality neurologic care for resource-limited populations in the U.S. and in low-middle-income countries, she conducts epidemiologic, health services, and clinical research aimed at determining risk factors for neurologic morbidity and mortality in these settings.

    In 2009, Dr Elafros began conducting research in Zambia focused on the medical and psychosocial burden of neurologic disease. Since then, she has been continuously involved in research with patients, caregivers, and healthcare workers regarding the most pressing neurologic concerns in sub-Saharan Africa. Her first NIH-funded study examined barriers to care for meningitis, a condition that continues to cause significant mortality and morbidity worldwide. In August 2023, she launched the Zambian Cohort of Healthy Aging and Dementia (Z-CHAD) study in collaboration with Zambian neurologists and neuropsychologists. This study is determining the prevalence of dementia and associated risk factors in Zambia while also characterizing the burden and barriers to care faced by these patients and their caregivers.

    Dr. Elafros also has an active research and clinical practice in Michigan. The Flint Neuropathy Study is an ongoing collaboration with Hurley Medical Center and McLaren Flint examining the prevalence of neuropathy and dementia in a predominantly Black, low-income primary care population. This work is formally characterizing barriers to neuropathy and dementia diagnosis and management in this population, which will then serve as the basis for interventions improving the management of brain and nerve health in this setting.

    Dr. Elafros' research has been funded by the National Institutes of Health, American Medical Association, American Academy of Neurology, and American Neurological Association. She has authored several peer-reviewed publications and is in demand as a speaker at leading institutions around the world. She is dedicated to capacity building and has mentees in three countries.

    Qualifications

    • Fellowship
      University of Michigan, Neuromuscular, Ann Arbor, MI, United States
      2020 - 2021
      Postdoctoral Fellowship
    • Residency
      Johns Hopkins Hospital, Adult Neurology, Baltimore, United States
      2017 - 2020
      Residency
    • Internship
      Johns Hopkins Hospital, Department of Medicine, Baltimore, United States
      2016 - 2017
      Internship
    • M.D.
      Michigan State University, East Lansing, MI, United States
      2008 - 2016
    • Ph.D., Epidemiology
      Michigan State University, East Lansing, MI, United States
      2008 - 2014
    • B.A., Spanish
      Michigan State University, East Lansing, MI, United States
      2004 - 2008
    • B.S., Human Biology
      Michigan State University, East Lansing, MI, United States
      2004 - 2008
    • M.A., Bioethics
      Michigan State University, East Lansing, MI, United States
      2006 - 2008

    Center Memberships

    • Center Member
      Caswell Diabetes Institute
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      Center for Global Health Equity
    • Center Member
      Global REACH

    Research Overview

    - Identification of risk factors for neurologic diseases in resource-limited regions of the United States and in low-middle income countries.
    - Characterization of the psychosocial burden of neurologic diseases, including stigma, among affected individuals and their social networks.
    - Identifying and addressing barriers to improve access to quality neurologic care and services for resource-limited populations.

    Recent Publications

    See All Publications
    • Journal Article
      Prevalence and Risk Factors of Distal Symmetric Polyneuropathy Among Predominantly Non-Hispanic Black, Low-Income Patients
      Elafros MA, Brown A, Marcus H, Dawood T, Bachuwa GI, Banerjee M, Winch PJ, Kvalsund M, Feldman EL, Skolarus LE, Callaghan BC. Neurology, 2024 May 8; 102 (11): DOI:10.1212/WNL.0000000000209390
      PMID: 38718313
    • Journal Article
      Patient and health care provider knowledge of diabetes and diabetic microvascular complications: a comprehensive literature review
      Elafros MA, Callaghan BC, Skolarus LE, Vileikyte L, Lawrenson JG, Feldman EL. Reviews in Endocrine and Metabolic Disorders, 2023 Apr 1; 24 (2): 221 - 239. DOI:10.1007/s11154-022-09754-5
      PMID: 36322296
    • Journal Article
      Towards prevention of diabetic peripheral neuropathy: clinical presentation, pathogenesis, and new treatments
      Elafros MA, Andersen H, Bennett DL, Savelieff MG, Viswanathan V, Callaghan BC, Feldman EL. Lancet Neurology, 2022 Oct 1; 21 (10): 922 - 936. DOI:10.1016/S1474-4422(22)00188-0
      PMID: 36115364
    • Journal Article
      The Global Burden of Polyneuropathy-In Need of an Accurate Assessment.
      Elafros MA, Kvalsund MP, Callaghan BC. JAMA neurology, 2022 Aug 6; 79 ((6)): 537 - 538.
    • Journal Article
      A qualitative study of patient, caregiver, doctor and nurse views of factors influencing lumbar puncture uptake in Zambia
      Elafros MA, Belessiotis-Richards C, Birbeck GL, Bond V, Sikazwe I, Kvalsund MP. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2022 Apr 1; 116 (4): 322 - 327. DOI:10.1093/trstmh/trab124
      PMID: 34352890
    • Journal Article
      A qualitative study of factors resulting in care delays for adults with meningitis in Zambia.
      Elafros MA, Bwalya C, Muchanga G, Mwale M, Namukanga N, Birbeck GL, Chomba M, Mugala-Mulenga A, Kvalsund MP, Sikazwe I, Saylor DR, Winch PJ. Transactions of the Royal Society of Tropical Medicine and Hygiene, 2022 Aug 6;
    • Journal Article
      The Global Burden of Polyneuropathy-In Need of an Accurate Assessment
      Elafros MA, Kvalsund MP, Callaghan BC. JAMA Neurol., 2022 Jan 1; 10.1001:
    • Journal Article
      Lumbar puncture-related knowledge, attitudes, and practices among patients, caregivers, doctors, and nurses in Zambia
      Elafros MA, Belessiotis-Richards C, Birbeck GL, Bond V, Sikazwe I, Kvalsund MP. American Journal of Tropical Medicine and Hygiene, 2021 May 5; 104 (5): 1925 - 1931. DOI:10.4269/ajtmh.20-0509
      PMID: 33755588

    Featured News & Stories

    Dr. Melissa Elafros on stage receiving her Global Achievement Award with the other recipients.
    Research News

    Dr. Elafros Receives Global Achievement Award

    The Johns Hopkins Alumni Association honored Melissa Elafros, M.D., Ph.D., at its annual Alumni Association Awards Celebration.
    A map from the Alzheimer's disease atlas showing population
    Research News

    Alzheimer's Disease Atlas featured Z-CHAD study

    The Zambia Cohort for Healthy Aging & Dementia (Z-CHAD) study was highlighted by Alzheimer's Disease International.
    Department News

    Who gets Alzheimer's drugs? Race, vulnerability and health status shape access

    The findings, published in Neurology, highlight potential disparities in access to a new class of Alzheimer's treatments as use of these therapies increases.
    prescription pad drawn
    Health Lab

    Who gets Alzheimer’s drugs? Race, vulnerability and health status shape access

    A Michigan Medicine study found major disparities in access to new Alzheimer’s drugs, with Black and Hispanic patients less likely to receive treatment, though adherence was similar once therapy began.
    A study worker talking to a older woman and child on the front steps of a home in Lusaka, Zambia
    Research News

    Dr. Elafros receives new grant to expand dementia and aging study

    The award from the Center for Global Health Equity supports a population-based study on aging and dementia in Zambia.
    Dr. Parul Sud (McLaren-Flint), Lexi Brown (Michigan Medicine), Dr. Melissa Elafros (Michigan Medicine), Dr. Huda Marcus (Hurley Medical Center), Dr. Thair Dawood (Hurley Medical Center).
    Research News

    Flint NeuroHealth Partnership

    The Flint NeuroHealth Partnership is breaking new ground in how neurologic diseases are identified and managed right here in Michigan.