Mark C Bicket, MD, PhD, FASA

Mark Christopher Bicket, MD
Associate Professor of Anesthesiology
Program Director, Anesthesiology, Medical School
Associate Professor of Health Management and Policy, School of Public Health
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Available to mentor
Mark C Bicket, MD, PhD, FASA
Mark Christopher Bicket, MD
Associate Professor
  • About
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  • Qualifications
  • Center Memberships
  • Recent Publications
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  • About

    Mark C. Bicket, MD, PhD, F.A.S.A. is the Co-Director of the Overdose Prevention Engagement Network and Associate Professor at the University of Michigan Medical School with a joint appointment in the School of Public Health. A clinician-scientist and practicing physician anesthesiologist, his work has been supported by NIH, SAMHSA, the Foundation for Anesthesia Education and Research, and the Patient-Centered Outcomes Research Institute (PCORI). Dr. Bicket’s research, which has appeared in JAMA, BMJ, and Annals of Surgery, focuses on pain management and interventions to reduce opioid-related harms. He is the Principal Investigator of the PCORI-funded CARES trial (Comparing Analgesic Regimen Effectiveness and Safety), an international pragmatic randomized trial to examine the association between commonly prescribed treatments for postoperative pain with patient-reported outcomes at up to 6 months after surgery.

    Originally from Edmond, Oklahoma, Dr. Bicket completed his MD and PhD at Johns Hopkins, where he served as Chief Resident in anesthesiology. He completed pain medicine fellowship training at the Massachusetts General Hospital. Previously, he served as Director of the nationally recognized Pain Medicine Fellowship Program and Director of Pain Medicine Quality and Safety, where he led Johns Hopkins in creating its first system-wide pain management policy that impacted millions of patients receiving care there every year. Dr. Bicket served as a White House Fellow and has advised the National Academy of Medicine, Centers for Medicare and Medicaid Services, state governments, and national organizations. He maintains board certifications in pain medicine and anesthesiology and is a Fellow of the American Society of Anesthesiologists.

    Links

    • linkedin
    • @MarkBicket
    • Google Scholar Profile
    • The CARES Study
    • The CARES for Kids Study

    Qualifications

    • T32 Postdoctoral Fellowship
      Johns Hopkins University School of Medicine, Anesthesiology, Baltimore, United States
      2015 - 2017
      Postdoctoral Research
    • PhD
      Johns Hopkins University School of Public Health, Baltimore, MD, United States
      2015 - 2019
    • MD
      Johns Hopkins University School of Medicine, Baltimore, MD, United States
      2006 - 2010
    • BA, Economics (honors)
      University of Oklahoma, Norman, OK, United States
      2002 - 2006
    • BA, Mathematics (honors)
      University of Oklahoma, Norman, OK, United States
      2002 - 2006

    Center Memberships

    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Opioid Research Institute
    • Center Member
      Institute for Healthcare Policy and Innovation

    Recent Publications

    See All Publications
    • Journal Article
      Association between inpatient AUDIT-C alcohol screening scores and postoperative outcomes: a retrospective cohort study.
      Chen T, Fernandez AC, Evilsizer S, Chan C-L, Gunaseelan V, Waljee JF, Bicket MC. BMJ Open, 2026 Aug 4; 16 (8): e115746 DOI:10.1136/bmjopen-2025-115746
      PMID: 42552000
    • Journal Article
      What predicts postoperative opioid prescribing and consumption? A statewide analysis of surgical quality registry data.
      Song J, Li Y, Waljee JF, Gunaseelan V, Brummett CM, Englesbe M, Bicket MC. Pain Med, 2026 Aug 3; DOI:10.1093/pm/pnag101
      PMID: 42547970
    • Journal Article
      Gabapentin Prescribing in Adolescents: The Case for Deimplementation
      Kelley-Quon LI, Bicket MC. Anesthesiology, 2026 Jul 22; 145 (2): 277 - 279. DOI:10.1097/aln.0000000000006160
    • Journal Article
      An Honest Broker System for Secure Linkage of Opioid-related Clinical, Prescription, and Outcomes Data.
      Stathakios J, Brummett CM, Gunaseelan V, Kaleba EO, Waljee JF, Bicket MC. Anesthesiol Open, 2026 Jul; 1 (2): e0024 DOI:10.1097/ao9.0000000000000024
      PMID: PMC13412359
    • Journal Article
      US multicentre randomised controlled trial protocol: Comparing Analgesic Regimen Effectiveness and Safety after surgery trial for Kids (CARES for Kids).
      Lee JS, Bicket MC, Mansfield SA, Rabbitts JA, Van Horn A, Perrone EE, Chua K-P, Voepel-Lewis T, Waljee J, Brummet C, Hutmacher C, Li Y, Kelley-Quon LI, CARES for Kids Investigators . BMJ Open, 2026 May 28; 16 (5): e118728 DOI:10.1136/bmjopen-2026-118728
      PMID: 42208996
    • Presentation
      Using Real-World Evidence to Demonstrate Impact and Value
      Bicket M. 2026 Mar 31;
    • Journal Article
      Variation in Postdischarge Opioid Prescribing After Childbirth and Associated Procedures.
      Latack KR, Sarosi E, Moniz MH, Gunaseelan V, Waljee JF, Bicket MC, Townsel CD, Kane Low L, Peahl AF. Obstet Gynecol, 2026 May 28; DOI:10.1097/AOG.0000000000006332
      PMID: 42208072
    • Journal Article
      Clinical decision support to reduce opioid prescribing at discharge for inpatients undergoing surgery (LESS Study): An interrupted time series analysis
      Rolfzen ML, Daniel K, Shah K, Reha C, Mascha EJ, Muellner M, Bicket MC, Brummett CM, Waljee JF, Frangakis SG, Bohnert AS, Bartels K. 2026 Apr 21;

    Featured News & Stories

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    Health Lab

    What does cannabis 'rescheduling' mean for science and society?

    Medical cannabis (marijuana) has been rescheduled on the federal level, which could open the door for much more research than was possible before. Four Michigan Medicine experts comment.
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    Health Lab

    Post-operative prescription-fill patterns differ amongst patients on high dose opioids

    A team at University of Michigan Medical School noted a lack of evidence around prescription practices for patients who come to surgery on high doses of opioids for chronic conditions.
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    Health Lab

    Study examines trends for use of medications for opioid use disorder among surgical patients

    Mark Bicket, M.D., Ph.D., and his team examined trends in use of medications for opioid use disorder among surgical patients.
    Mark Bicket
    Department News

    Mark Bicket, MD, PhD, receives the American Society of Anesthesiologists James E. Cottrell, MD, Presidential Scholar Award

    Mark Bicket, MD, PhD, is the recipient of the 2025 American Society of Anesthesiologists (ASA) James E. Cottrell, MD, Presidential Scholar Award in recognition of his work to pioneer evidence-based approaches to patient-centered pain care.
    Prescription Bottles Illustration
    Department News

    What we still don’t know about long-term opioid therapy for pain

    In a recent Viewpoint column in JAMA, Mark Bicket, MD, PhD, an associate professor in the Department of Anesthesiology, unpacks new data presented to the FDA on the harms from long-term opioids and explores the evidence imbalance at the core of opioid policy and patient care.
    Mark Bicket
    Department News

    Mark Bicket, MD, PhD, named ASRA Pain Medicine Presidential Scholar

    The award is given biannually to recognize outstanding scientific and sustained contributions to regional anesthesia, acute, or chronic pain medicine over the preceding 10 years.