Mark C Bicket, MD, PhD, FASA
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About
Mark C. Bicket, MD, PhD, F.A.S.A. is the Co-Director of the Overdose Prevention Engagement Network and Associate Professor at the University of Michigan Medical School with a joint appointment in the School of Public Health. A clinician-scientist and practicing physician anesthesiologist, his work has been supported by NIH, SAMHSA, the Foundation for Anesthesia Education and Research, and the Patient-Centered Outcomes Research Institute (PCORI). Dr. Bicket’s research, which has appeared in JAMA, BMJ, and Annals of Surgery, focuses on pain management and interventions to reduce opioid-related harms. He is the Principal Investigator of the PCORI-funded CARES trial (Comparing Analgesic Regimen Effectiveness and Safety), an international pragmatic randomized trial to examine the association between commonly prescribed treatments for postoperative pain with patient-reported outcomes at up to 6 months after surgery.
Originally from Edmond, Oklahoma, Dr. Bicket completed his MD and PhD at Johns Hopkins, where he served as Chief Resident in anesthesiology. He completed pain medicine fellowship training at the Massachusetts General Hospital. Previously, he served as Director of the nationally recognized Pain Medicine Fellowship Program and Director of Pain Medicine Quality and Safety, where he led Johns Hopkins in creating its first system-wide pain management policy that impacted millions of patients receiving care there every year. Dr. Bicket served as a White House Fellow and has advised the National Academy of Medicine, Centers for Medicare and Medicaid Services, state governments, and national organizations. He maintains board certifications in pain medicine and anesthesiology and is a Fellow of the American Society of Anesthesiologists.
Links
linkedin @MarkBicket Google Scholar Profile The CARES Study The CARES for Kids Study
Qualifications
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T32 Postdoctoral FellowshipJohns Hopkins University School of Medicine, Anesthesiology, Baltimore, United States
2015 - 2017
Postdoctoral Research
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PhDJohns Hopkins University School of Public Health, Baltimore, MD, United States
2015 - 2019
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MDJohns Hopkins University School of Medicine, Baltimore, MD, United States
2006 - 2010
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BA, Economics (honors)University of Oklahoma, Norman, OK, United States
2002 - 2006
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BA, Mathematics (honors)University of Oklahoma, Norman, OK, United States
2002 - 2006
Center Memberships
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Center MemberAI and Digital Health Innovation
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Center MemberOpioid Research Institute
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Center MemberInstitute for Healthcare Policy and Innovation
Recent Publications
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Chen T, Fernandez AC, Evilsizer S, Chan C-L, Gunaseelan V, Waljee JF, Bicket MC. BMJ Open, 2026 Aug 4; 16 (8): e115746Journal ArticleAssociation between inpatient AUDIT-C alcohol screening scores and postoperative outcomes: a retrospective cohort study.
DOI:10.1136/bmjopen-2025-115746 PMID: 42552000 -
Song J, Li Y, Waljee JF, Gunaseelan V, Brummett CM, Englesbe M, Bicket MC. Pain Med, 2026 Aug 3;Journal ArticleWhat predicts postoperative opioid prescribing and consumption? A statewide analysis of surgical quality registry data.
DOI:10.1093/pm/pnag101 PMID: 42547970 -
Kelley-Quon LI, Bicket MC. Anesthesiology, 2026 Jul 22; 145 (2): 277 - 279.Journal ArticleGabapentin Prescribing in Adolescents: The Case for Deimplementation
DOI:10.1097/aln.0000000000006160 -
Stathakios J, Brummett CM, Gunaseelan V, Kaleba EO, Waljee JF, Bicket MC. Anesthesiol Open, 2026 Jul; 1 (2): e0024Journal ArticleAn Honest Broker System for Secure Linkage of Opioid-related Clinical, Prescription, and Outcomes Data.
DOI:10.1097/ao9.0000000000000024 PMID: PMC13412359 -
Lee JS, Bicket MC, Mansfield SA, Rabbitts JA, Van Horn A, Perrone EE, Chua K-P, Voepel-Lewis T, Waljee J, Brummet C, Hutmacher C, Li Y, Kelley-Quon LI, CARES for Kids Investigators . BMJ Open, 2026 May 28; 16 (5): e118728Journal ArticleUS multicentre randomised controlled trial protocol: Comparing Analgesic Regimen Effectiveness and Safety after surgery trial for Kids (CARES for Kids).
DOI:10.1136/bmjopen-2026-118728 PMID: 42208996 -
Bicket M. 2026 Mar 31;PresentationUsing Real-World Evidence to Demonstrate Impact and Value
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Latack KR, Sarosi E, Moniz MH, Gunaseelan V, Waljee JF, Bicket MC, Townsel CD, Kane Low L, Peahl AF. Obstet Gynecol, 2026 May 28;Journal ArticleVariation in Postdischarge Opioid Prescribing After Childbirth and Associated Procedures.
DOI:10.1097/AOG.0000000000006332 PMID: 42208072 -
Rolfzen ML, Daniel K, Shah K, Reha C, Mascha EJ, Muellner M, Bicket MC, Brummett CM, Waljee JF, Frangakis SG, Bohnert AS, Bartels K. 2026 Apr 21;Journal ArticleClinical decision support to reduce opioid prescribing at discharge for inpatients undergoing surgery (LESS Study): An interrupted time series analysis
Featured News & Stories
What does cannabis 'rescheduling' mean for science and society?
Post-operative prescription-fill patterns differ amongst patients on high dose opioids
Study examines trends for use of medications for opioid use disorder among surgical patients
Mark Bicket, MD, PhD, receives the American Society of Anesthesiologists James E. Cottrell, MD, Presidential Scholar Award
What we still don’t know about long-term opioid therapy for pain