Mark C Bicket, MD, PhD, FASA
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About
Mark C. Bicket, MD, PhD, F.A.S.A. is the Co-Director of the Overdose Prevention Engagement Network and Associate Professor at the University of Michigan Medical School with a joint appointment in the School of Public Health. A clinician-scientist and practicing physician anesthesiologist, his work has been supported by NIH, SAMHSA, the Foundation for Anesthesia Education and Research, and the Patient-Centered Outcomes Research Institute (PCORI). Dr. Bicket’s research, which has appeared in JAMA, BMJ, and Annals of Surgery, focuses on pain management and interventions to reduce opioid-related harms. He is the Principal Investigator of the PCORI-funded CARES trial (Comparing Analgesic Regimen Effectiveness and Safety), an international pragmatic randomized trial to examine the association between commonly prescribed treatments for postoperative pain with patient-reported outcomes at up to 6 months after surgery.
Originally from Edmond, Oklahoma, Dr. Bicket completed his MD and PhD at Johns Hopkins, where he served as Chief Resident in anesthesiology. He completed pain medicine fellowship training at the Massachusetts General Hospital. Previously, he served as Director of the nationally recognized Pain Medicine Fellowship Program and Director of Pain Medicine Quality and Safety, where he led Johns Hopkins in creating its first system-wide pain management policy that impacted millions of patients receiving care there every year. Dr. Bicket served as a White House Fellow and has advised the National Academy of Medicine, Centers for Medicare and Medicaid Services, state governments, and national organizations. He maintains board certifications in pain medicine and anesthesiology and is a Fellow of the American Society of Anesthesiologists.
Links
linkedin @MarkBicket Google Scholar Profile The CARES Study The CARES for Kids Study
Qualifications
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T32 Postdoctoral FellowshipJohns Hopkins University School of Medicine, Anesthesiology, Baltimore, United States
2015 - 2017
Postdoctoral Research
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PhDJohns Hopkins University School of Public Health, Baltimore, MD, United States
2015 - 2019
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MDJohns Hopkins University School of Medicine, Baltimore, MD, United States
2006 - 2010
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BA, Economics (honors)University of Oklahoma, Norman, OK, United States
2002 - 2006
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BA, Mathematics (honors)University of Oklahoma, Norman, OK, United States
2002 - 2006
Center Memberships
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Center MemberAI and Digital Health Innovation
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Center MemberOpioid Research Institute
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Center MemberInstitute for Healthcare Policy and Innovation
Recent Publications
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Stathakios J, Tsai RN, Lai Y, Gunaseelan V, Brummett C, Chapman AJ, Waljee J, Hemmila MR, Bicket MC. Journal of Trauma and Acute Care Surgery, 2026 Oct 16;Journal ArticleOpioid prescribing and hospital outcomes after trauma in patients with substance use disorder: An analysis of the michigan trauma quality improvement project
DOI:10.1097/ta.0000000000005202 -
Stathakios J, Tsai RN, Marzoughi M, Gardner M, Szczygiel LA, Lagisetty P, Waljee J, Bicket MC. Surgery, 2026 Sep 25; 201: 110701Journal ArticleSurgery is not the end of the story: Challenges and strategies in the postoperative care of patients receiving long-term opioid therapy.
DOI:10.1016/j.surg.2026.110701 PMID: 42887410 -
Saleh N, Bicket M, Chua K-P, Hanna M. 2026 Aug 26;Additional ScholarshipExing the X-Waiver: Has It Made a Difference in Buprenorphine Prescribing?
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Saleh N, Bicket M, Chua K-P, Hanna M. 2026 Aug 26;Additional ScholarshipExing the X-Waiver: Has It Made a Difference in Buprenorphine Prescribing?
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Chen T, Fernandez AC, Evilsizer S, Chan C-L, Gunaseelan V, Waljee JF, Bicket MC. BMJ Open, 2026 Aug 4; 16 (8): e115746Journal ArticleAssociation between inpatient AUDIT-C alcohol screening scores and postoperative outcomes: a retrospective cohort study.
DOI:10.1136/bmjopen-2025-115746 PMID: 42552000 -
Song J, Li Y, Waljee JF, Gunaseelan V, Brummett CM, Englesbe M, Bicket MC. Pain Med, 2026 Aug 3;Journal ArticleWhat predicts postoperative opioid prescribing and consumption? A statewide analysis of surgical quality registry data.
DOI:10.1093/pm/pnag101 PMID: 42547970 -
Kelley-Quon LI, Bicket MC. Anesthesiology, 2026 Jul 22; 145 (2): 277 - 279.Journal ArticleGabapentin Prescribing in Adolescents: The Case for Deimplementation
DOI:10.1097/aln.0000000000006160 -
Stathakios J, Brummett CM, Gunaseelan V, Kaleba EO, Waljee JF, Bicket MC. Anesthesiol Open, 2026 Jul; 1 (2): e0024Journal ArticleAn Honest Broker System for Secure Linkage of Opioid-related Clinical, Prescription, and Outcomes Data.
DOI:10.1097/ao9.0000000000000024 PMID: PMC13412359
Featured News & Stories
What does cannabis 'rescheduling' mean for science and society?
Post-operative prescription-fill patterns differ amongst patients on high dose opioids
Study examines trends for use of medications for opioid use disorder among surgical patients
Mark Bicket, MD, PhD, receives the American Society of Anesthesiologists James E. Cottrell, MD, Presidential Scholar Award
What we still don’t know about long-term opioid therapy for pain