Heng Lin
Research Assistant Professor
Surgery
Medical School
[email protected]
Available to mentor
Heng Lin
Research Assistant Professor
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Recent Publications
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Lin H, Tison K, Du Y, Kirchhoff P, Kim C, Wang W, Yang H, Pitter M, Yu J, Liao P, Zhou J, Vatan L, Grove S, Wei S, Vigil T, Shah YM, Mortensen R, Kryczek I, Garmire L, Sivaccumar JP, Ramesh AK, Zhang N, An Z, Wang S, Zou W. The Journal of Immunology, 2025 Nov 23; 214 (Supplement_1):Journal ArticleItaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance 2251
DOI:10.1093/jimmun/vkaf283.189 -
Zhou J, Tison K, Zhou H, Bai L, Acharyya RK, McEachern D, Metwally H, Wang Y, Pitter M, Choi JE, Vatan L, Liao P, Yu J, Lin H, Jiang L, Wei S, Gao X, Grove S, Parolia A, Cieslik M, Kryczek I, Green MD, Lin JX, Chinnaiyan AM, Leonard WJ, Wang S, Zou W. Nature, 2025 Jul 10; 643 (8071): 519 - 528.Journal ArticleSTAT5 and STAT3 balance shapes dendritic cell function and tumour immunity
DOI:10.1038/s41586-025-09000-3 PMID: 40369063 -
Bao Y, Cruz G, Zhang Y, Qiao Y, Mannan R, Hu J, Yang F, Gondal M, Shahine M, Kang S, Mahapatra S, Chu A, Choi JE, Yu J, Lin H, Miner SJ, Robinson DR, Wu YM, Zheng Y, Cao X, Su F, Wang R, Hosseini N, Cieslik M, Kryczek I, Vaishampayan U, Zou W, Chinnaiyan AM. Cancer Discovery, 2025 Feb 1; 15 (2): 363 - 381.Journal ArticleThe UBA1–STUB1 Axis Mediates Cancer Immune Escape and Resistance to Checkpoint Blockade
DOI:10.1158/2159-8290.CD-24-0435 PMID: 39540840 -
Valvo VM, Zhang Q, Jiang L, Holcomb EA, Pearson AN, Edmunds AG, Faulkner HG, James JG, Tate A, Huber AK, Wang Z, Guo Y, Karnak D, Parsels LA, Parsels JD, Lei YL, Rehemtulla A, Lin H, Carpenter ES, Wahl DR, Sahai V, Lawrence TS, Green MD, Morgan MA. Mol Cancer Ther, 2025 Mar 10; OF1 - OF16.Journal ArticleOlaparib and Radiotherapy Induce Type I Interferon- and CD8+ T Cell-Dependent Sensitization to Immunotherapy in Pancreatic Cancer.
DOI:10.1158/1535-7163.MCT-24-0210 -
Lin H, Tison K, Du Y, Kirchhoff P, Kim C, Wang W, Yang H, Pitter M, Yu J, Liao P, Zhou J, Vatan L, Grove S, Wei S, Vigil T, Shah YM, Mortensen R, Kryczek I, Garmire L, Sivaccumar JP, Ramesh AK, Zhang N, An Z, Wang S, Zou W. Cancer Cell, 2024 Dec 9; 42 (12): 2032 - 2044.e6.Journal ArticleItaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance
DOI:10.1016/j.ccell.2024.10.010 PMID: 39515327 -
Choi JE, Qiao Y, Kryczek I, Yu J, Gurkan J, Bao Y, Gondal M, Tien JCY, Maj T, Yazdani S, Parolia A, Xia H, Zhou JJ, Wei S, Grove S, Vatan L, Lin H, Li G, Zheng Y, Zhang Y, Cao X, Su F, Wang R, He T, Cieslik M, Green MD, Zou W, Chinnaiyan AM. Nature Communications, 2024 Dec 1; 15 (1):Journal ArticlePIKfyve, expressed by CD11c-positive cells, controls tumor immunity
DOI:10.1038/s41467-024-48931-9 PMID: 38942798 -
Choi JE, Qiao Y, Kryczek I, Yu J, Gurkan J, Bao Y, Tien J, Maj T, Yazdani S, Parolia A, Xia H, Zhou J, Wei S, Grove S, Vatan L, Lin H, Li G, Zheng Y, Zhang Y, Cao X, Su F, Rui W, He T, Gondal M, Cieslik M, Green M, Zou W, Chinnaiyan A. bioRxiv, 2023 Jun 29;Journal ArticlePIKfyve controls dendritic cell function and tumor immunity
DOI:10.1038/s41467-024-48931-9 -
Yu J, Yan Y, Li S, Xu Y, Parolia A, Rizvi S, Wang W, Zhai Y, Xiao R, Li X, Liao P, Zhou J, Okla K, Lin H, Lin X, Grove S, Wei S, Vatan L, Hu J, Szumilo J, Kotarski J, Freeman ZT, Skala S, Wicha M, Cho KR, Chinnaiyan AM, Schon S, Wen F, Kryczek I, Wang S, Chen L, Zou W. Cell, 2024 Jul 5;Journal ArticleProgestogen-driven B7-H4 contributes to onco-fetal immune tolerance
DOI:10.1016/j.cell.2024.06.012
