David M Fresco

David M. Fresco
Professor of Psychiatry, Medical School
Research Professor, Survey Research Center, Institute for Social Research
Office:
University of Michigan
Department of Psychiatry
2559 Rachel Upjohn Building, 4250 Plymouth Road
Ann Arbor, Michigan 48109-2435
Available to mentor
David M Fresco
David M. Fresco
Professor
  • About
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  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    David M. Fresco is Professor of Psychiatry and Research Professor at the Institute for Social Research (ISR), Director of the omHealth Lab (ॐ+mHealth), Research Director for Michigan Mindfulness.

    Links

    • Michigan Mindfulness
    • Data Science for Dynamic Intervention Decision Making Center (d3c)
    • omHealth (ॐ+mHealth)

    Qualifications

    • Postdoctoral Fellow
      Temple University, Psychology, Philadelphia, United States
      1999 - 2001
      Postdoctoral Fellowship
    • PhD
      University of North Carolina, Chapel Hill, NC, United States
      1991 - 1999
    • MA, Clinical Psychology
      University of North Carolina, Davie Hall, Chapel Hill, NC, 27599, United States
      1991 - 1994
    • BA
      Temple University, Philadelphia, PA, United States
      1986 - 1990

    Center Memberships

    • Center Member
      Eisenberg Family Depression Center

    Research Overview

    His program of research adopts an affective neuroscience perspective to conduct basic, translational, and treatment studies of anxiety and mood disorders, particularly distress disorders (e.g., major depressive disorder, generalized anxiety disorder, and post-traumatic stress disorder) incorporating methodologies including functional neuroimaging (fMRI & EEG), peripheral psychophysiology, and serum markers (e.g., inflammation, neurodegeneration).

    Another facet of Dr. Fresco’s research has focused on the development of treatments informed by affective and contemplative neuroscience findings that incorporate mindfulness meditation and other practices derived from Buddhist mental training exercises.
    Increasingly, with collaborators at ISR within the Data Science for Dynamic Intervention Decision-Making Center (d3c). Dr. Fresco has initiated clinical trials for treatment optimization and implementation utilizing adaptive intervention methodology (e.g., sequential multiple assignment randomized trials [SMART] & just-in-time adaptive interventions [JITAIs]).

    Dr. Fresco has also joined and contributed to the Strong Minds and Enhanced Vision initiative at the Kellogg Eye Center, University of Michigan, led by Dr. Thiran Jayasundera, which aims to characterize and resolve the emotional distress experienced by vision patients as they confront the possibility and eventuality of vision loss.

    Much of his current and recent NIH-funded research has focused on examining neurobehavioral mechanisms and efficacy of mindfulness-enriched treatments for chronic illnesses, and the role of emotion regulation strategies in everyday life to reduce distress.

    Recent Publications

    See All Publications
    • Proceeding / Abstract / Poster
      Treatment credibility and therapeutic alliance in an RCT of two active psychotherapies for cancer caregivers
      Loschiavo MJ, Gebert RR, Jacobs JM, Hoyt MA, Mennin DS, Fresco DM, Dunderdale LE, Applebaum AJ. 2027 Mar 18;
    • Proceeding / Abstract / Poster
      Markers of Success in rt-fMRI-NF Targeting the Prefrontal Cortex and Alternate Region Controls During Emotion Regulation
      Russman Block S, Peltier S, Hovakimian S, Mannella K, Litinas K, Fitzgerald K, Fresco D, Taylor S. 2026 Oct 8;
    • Journal Article
      Investigating functional impairment as a mediator of the association between internalising symptoms and low wellbeing
      Sgherza TR, Becerra R, Bylsma LM, Fresco DM, Naragon-Gainey K. Journal of Affective Disorders, 2026 Jul 15; 405: DOI:10.1016/j.jad.2026.121517
      PMID: 41763322
    • Journal Article
      Changes in Phasic Heart Rate Variability Predict Clinical Outcomes Following Emotion Regulation Therapy for Generalized Anxiety Disorder and Comorbid Depression
      Szkutak A, Lee HH, Quintero JM, Aldao A, Fresco DM, Mennin DS. Behavior Therapy, 2026 Jul 1; 57 (4): 640 - 653. DOI:10.1016/j.beth.2026.02.001
      PMID: 42276683
    • Proceeding / Abstract / Poster
      0476 Mindfulness Enhances Antidepressant Outcomes for Pregnant Women with Insomnia and Depression: A Comparative Effectiveness Randomized Controlled Trial
      Afaneh H, Kalmbach D, Cheng P, Reffi A, Jennings M, Hirata M, Pitts D, Ong J, Fresco D, Swanson L, O'Brien L, Drake C. Sleep, 2026 May 10; 49 (Supplement_1): a212 - a212. DOI:10.1093/sleep/zsag091.0475
    • Proceeding / Abstract / Poster
      Linguistic Expression and Cognitive Reappraisal Success: Pilot Findings from Real-Time fMRI Neurofeedback Training
      Hovakimian S, Litinas K, Mannella K, Fresco D, Peltier SJ, Taylor S, Russman Block S. 2026 Apr 1;
    • Proceeding / Abstract / Poster
      The Effects of Real-Time fMRI Neurofeedback on Emotion Regulation in Adult with and Without Anxiety: A pilot study
      Russman Block S, Hovakimian S, Mannella K, Litinas K, Fitzgerald K, Fresco D, Peltier SJ, Taylor S. 2026 Apr 1;
    • Journal Article
      Mindfulness-imbued insomnia therapy enhances antidepressant outcomes for pregnant women with insomnia and depression: A comparative effectiveness randomized controlled trial of CBTI and PUMAS
      Kalmbach D, Afaneh H, Cheng P, Reffi A, Jennings M, Hirata M, Pitts D, Ong JC, Fresco DM, Swanson L, O'Brien L, Drake C. Sleep Medicine, 2026 Jan 31; 138: 107360 DOI:10.1016/j.sleep.2025.107360