Available to mentor
Matthew Patrick, MEng, PhD is a Research Assistant Professor of Dermatology at the University of Michigan Medical School, and is a member of the Cutaneous Bioinformatics Research Program. Dr. Patrick is pursuing research focused upon translational bioinformatics, particularly on providing biological inference from high dimensional data for dermatological research.
Dr. Patrick received his PhD in Computer Science from University of York in the United Kingdom in 2013. He completed postdoctoral research training in Epidemiology and Modelling at the University of Cambridge before joining the U-M Department of Dermatology in 2016 as a postdoctoral research fellow working with Dr. Lam C. (Alex) Tsoi in the Cutaneous Bioinformatics Program. He joined the U-M Department of Dermatology faculty in 2020.
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Center MemberPrecision Health Initiative
- Applying mathematical, statistical and computational approaches to understand the behaviours of complex systems.
- Using advanced machine learning and optimisation techniques to address challenging problems.
- Testing and evaluating the implications of data and software quality for scientific research.
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Bogle R, Patrick MT, Sreeskandarajan S, Gharaee-Kermani M, Zhang H, Li Q, Zhou R, Ma F, Kahlenberg JM, Plazyo O, Elder JT, Billi AC, Gudjonsson JE, Tsoi LC. J Invest Dermatol, 2024 Sep 27;Journal ArticleProfiling lncRNA in psoriatic skin using scRNA-seq.
DOI:10.1016/j.jid.2024.09.010 PMID: 39342985 -
Wu Y, Chaskar P, Wasikowski R, Patrick MT, Julia V, Gudjonsson JE, Tsoi LC. Journal of Investigative Dermatology, 2024 Aug; 144 (8): s71Proceeding / Abstract / Poster410 Modeling prurigo nodularis and atopic dermatitis lesional skin identifies disease-biased regulatory mechanisms using single cell multiomic data
DOI:10.1016/j.jid.2024.06.426 -
Oliva M, Sarkar MK, March ME, Saeidian AH, Mentch FD, Hsieh C-L, Tang F, Uppala R, Patrick MT, Li Q, Bogle R, Kahlenberg JM, Watson D, Glessner JT, Tsoi LC, Hakonarson H, Gudjonsson JE, Smith KM, Riley-Gillis B. medRxiv, 2024 Jun 19;Journal ArticleMulti-ancestry Genome-Wide Association Meta-Analysis Identifies Novel Loci in Atopic Dermatitis.
DOI:10.1101/2024.06.17.24308897 PMID: 38946956 -
Shaked G, Zhang H, Zhang Z, Gudjonsson JE, Elder JT, Patrick MT, Tsoi LC. bioRxiv 2024.06.03.595407,Journal ArticleLoopsim: Enrichment Analysis of Chromosome Conformation Capture with Fast Empirical Distribution Simulation
DOI:10.1101/2024.06.03.595407 -
Ma F, Gharaee-Kermani M, Tsoi LC, Plazyo O, Chaskar P, Harms P, Patrick MT, Xing X, Hile G, Piketty C, Lazzari A, Van Delm W, Maverakis E, Nakamura M, Modlin RL, Kahlenberg JM, Billi AC, Julia V, Krishnaswamy JK, Gudjonsson JE. J Allergy Clin Immunol, 2024 Jan; 153 (1): 146 - 160.Journal ArticleSingle-cell profiling of prurigo nodularis demonstrates immune-stromal crosstalk driving profibrotic responses and reversal with nemolizumab.
DOI:10.1016/j.jaci.2023.07.005 PMID: 37506977 -
Patrick MT, Sreeskandarajan S, Shefler A, Wasikowski R, Sarkar MK, Chen J, Qin T, Billi AC, Kahlenberg JM, Prens E, Hovnanian A, Weidinger S, Elder JT, Kuo C-C, Gudjonsson JE, Tsoi LC. JCI Insight, 2023 Dec 22; 8 (24):Journal ArticleLarge-scale functional inference for skin-expressing lncRNAs using expression and sequence information.
DOI:10.1172/jci.insight.172956 PMID: 38131377 -
Zhang H, Patrick MT, Tejasvi T, Sarkar MK, Wasikowski R, Stuart PE, Li Q, Xing X, Voorhees JJ, Ward NL, He K, Zhou X, Gudjonsson JE, Nair RP, Elder JT, Tsoi LC. Br J Dermatol, 2023 Dec 20; 190 (1): 70 - 79.Journal ArticleRetrospective pharmacogenetic study of psoriasis highlights the role of KLK7 in tumour necrosis factor signalling.
DOI:10.1093/bjd/ljad332 PMID: 37672660 -
Patrick MT, Li Q, Ward NL, Gudjonsson JE, Elder JT, Tsoi LC. Journal of Investigative Dermatology, 2023 Nov; 143 (11): s340Proceeding / Abstract / Poster44 Predicting individuals with psoriasis at risk from multiple sclerosis
DOI:10.1016/j.jid.2023.09.052
