Wajd N Al-Holou, MD

Wajd N. Al-Holou
Assistant Professor of Neurosurgery and Co-Director, CNS Tumor Registry
Medical School
Office:
University of Michigan
Neurosurgery
1500 E. Medical Center Drive, 3470 Taubman Center
Ann Arbor, MI 48109-5338
Email:
[email protected]
Available to mentor
Wajd N Al-Holou, MD
Wajd N. Al-Holou
Assistant Professor
  • Qualifications
  • Recent Publications
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  • Qualifications

    • Clinical Fellow
      University of Texas, MD Anderson Cancer Center, Neurosurgical Oncology, United States
      2016 - 2017
      Postdoctoral Fellowship
    • Residency
      University of Michigan, Neurosurgery, Ann Arbor, United States
      2009 - 2016
      Residency
    • Chief Resident
      University of Michigan, Neurosurgery, Ann Arbor, USA
      2015 - 2016
      Chief Resident
    • MD
      University of Michigan, Ann Arbor, MI, United States
      2004 - 2009
    • BS
      University of Detroit Mercy, Detroit, United States
      2000 - 2003

    Recent Publications

    See All Publications
    • Proceeding / Abstract / Poster
      The prevalence and natural history of pineal cysts in adults
      Terman S, Al-Holou WN, Kilburg C, Garton HJL, Maher CO. 2011 Apr 4;
    • Presentation
      Academic Neurosurgical Oncology: How to Start a Brain Tumor Practice
      Al-Holou W. 2026 Sep 1;
    • Journal Article
      Predicting postoperative hospice enrollment following stereotactic brain biopsy: a retrospective study and risk score development.
      Tripathy A, Harake ES, Ahmad A, Sharba N, Li A, Saleh S, Sagher O, Heth JA, Altshuler D, Hollon TC, Thompson BG, Pandey AS, Umemura Y, Al-Holou WN. J Neurosurg, 2026 Jul 31; 1 - 13. DOI:10.3171/2026.2.JNS251994
      PMID: 42537242
    • Presentation
      Building a Comprehensive  Clinical and Translational Brain Tumor Program
      Al-Holou W. 2026 Sep 1;
    • Journal Article
      Cutting through complexity: Spatial multi-omics in the fight against diffuse intrinsic pontine glioma/diffuse midline glioma
      Vo T, Savary C, Jackson ER, Douglas AM, Murdoch HJ, Jayaraman R, Bessler N, Persson ML, McEwen H, McLachlan T, Duchatel RJ, Petraello B, Agnihotri S, Anastas J, Baker SJ, Becher OJ, Castel D, Chavez L, Koldobskiy MA, Deogharkar A, Mota M, Dirks PB, Doherty R, de la Nava D, Duncan B, du Chatinier A, Galban S, Marques JG, Hanson CM, Hara T, Herrington C, Ji S, Jones C, Kleinman CL, Krug B, Lin FY, Lu QR, Messinger D, Mody RJ, Mukherji D, Parthasarathy A, Peterson E, Phoenix TN, Pichumani K, Prensner JR, Ramakrishna S, Ramsoomair CK, Sajjakulnukit P, Sarmashghi S, Syed S, Tamplin OJ, Trout M, Freytag S, Valvo VM, Wahl DR, Al-Holou WN, Wechsler-Reya RJ, Koschmann C, Venneti S, Filbin MG, Dun MD. Neuro-Oncology Pediatrics, 2026 Jun 7; 2 (3): wuag036 DOI:10.1093/neuped/wuag036
    • Proceeding / Abstract / Poster
      393 THY1: A Therapeutically Targetable Mediator of Treatment Resistance in H3K27M Pediatric Tumors
      Syed S, Tripathy A, Ji S, Alomary Y, de la Nava Martin D, Mota M, Chakravarthy R, Huang D-L, Wang Z, Li Z, Zhang Q, Lawrence T, Wahl D, Koschmann C, Venneti S, Rehemtulla A, Al-Holou W. Neurosurgery, 2026 Apr 24; 72 (Supplement_1): 109 - 109. DOI:10.1227/neu.0000000000003964_393
    • Journal Article
      A blueprint for local and distal glioblastoma invasion programs
      Chanoch-Myers R, Hara T, Greenwald AC, Hoefflin R, Bussema L, Weisman HR, Nieblas-Bedolla E, Gurramkonda J, Bekezhankyzy Z, Jucht A, Fernandez E, Spitzer A, Hon Fung J, Biella C, Al-Holou W, Camelo-Piragua S, Behnan J, Galli R, Wakimoto H, Suva ML, Tirosh I. Nature Communications, 2026 Mar 12; DOI:10.1038/s41467-026-70470-8
    • Journal Article
      Minimizing the risks of stereotactic brain biopsy in suspected central nervous system lymphoma: a retrospective database study
      Li A, Saleh S, Sharba N, Guivatchian E, Sagher O, Sullivan SE, Heth JA, Hollon TC, Thompson BG, Pandey AS, Umemura Y, Al-Holou WN. Journal of Cancer Research and Clinical Oncology, 2026 Mar 1; 152 (3): DOI:10.1007/s00432-026-06458-0
      PMID: 41886097

    Featured News & Stories

    Department News

    Brain cancer digital twin predicts treatment outcomes

    A new machine-learning-based approach to mapping real-time tumor metabolism in brain cancer patients, developed at the University of Michigan, could help doctors discover which treatment strategies are most likely to be effective against individual cases of glioma.
    doctor talking to patient in clinic in white coat
    Health Lab

    I've been diagnosed with a brain tumor. Now what?

    Facing a brain tumor diagnosis can be an overwhelming experience, but it’s essential to gather information that will help guide the next steps in your care. University of Michigan Health neurosurgeon Wajd Al-Holou, M.D., weighs in on the importance of understanding the diagnosis, exploring various treatment options and seeking the best medical care.
    Max Wicha, M.D. and Sunitha Nagrath, Ph.D.  Photo credit: Leisa Thompson
    Illuminate

    Nurturing High-Risk, High-Reward Ideas

    The Forbes Institute fosters cross-disciplinary collaboration, encouraging partnerships among faculty from various disciplines across the University of Michigan campus. Learn more about their research into tumor dormancy.
    woman smiling after brain surgery with brain wrapped in white cloth and in blue hospital gown on grey background
    Health Lab

    Aggressive brain cancer doesn’t stop woman’s positive perspective

    Despite a devastating diagnosis of glioblastoma, Chris Barry is thankful for her family, friends and the care she’s receiving at Michigan Medicine.
    older daughter hugging and kissing her mom outside with blue sky by a rock
    Health Lab

    After daughter’s brain surgery, mom sells art to raise money for cancer research 

    Nearly four and half years after her daughter’s lifesaving surgery to remove a glioma, a Michigan artist continues to raise money towards research for the treatment of cancerous brain tumors by selling her work.