Jeffrey Berinstein, MD, MSc

berinstein-jeffrey
Assistant Professor of Internal Medicine
Medical School
Office:
University of Michigan
Department of Internal Medicine, Division of Gastroenterology and Hepatology
1500 E. Medical Center Dr.
Ann Arbor, MI
Email:
[email protected]
Available to mentor
Jeffrey Berinstein, MD, MSc
berinstein-jeffrey
Assistant Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • Manage Your Profile

  • About

    I am an NIH-funded clinician-scientist and Assistant Professor of Medicine in the Division of Gastroenterology and Hepatology at the University of Michigan. My clinical and research program focuses on improving the care of patients with inflammatory bowel disease, particularly those with acute severe ulcerative colitis (ASUC(. My work integrates clinical investigation, pragmatic and adaptive clinical trial design, prediction modeling, and implementation of evidence-based care pathways to improve treatment selection and clinical outcomes.

    Qualifications

    • Clinical Trials Academy II
      University of Michigan, Ann Arbor, United States
      2024 - 2025
      Other
    • Clinical Trials Academy I
      University of Michigan, Ann Arbor, United States
      2022 - 2022
      Other
    • Fellow
      University of Michigan–Ann Arbor, Gastroenterology and Hepatology, Ann Arbor, United States
      2018 - 2021
      Postdoctoral Fellowship
    • Chief Fellow University of Michigan Health System, Ann Arbor, Michigan
      University of Michigan Health System, Internal Medicine- Gastroenterology, Ann Arbor, MI, United States
      2020 - 2021
      Chief Resident
    • Resident
      University of Michigan, Internal Medicine, Ann Arbor, MI, United States
      2015 - 2018
      Residency
    • MSc, Health and Healthcare Research
      University of Michigan–Ann Arbor, Ann Arbor, United States
      2018 - 2019
    • MD
      Technion – Israel Institute of Technology, Haifa, Israel
      2011 - 2015
    • BSc, Molecular Biology, Honors
      McMaster University, Hamilton, Canada
      2006 - 2010

    Center Memberships

    • Center Member
      Institute for Healthcare Policy and Innovation

    Research Overview

    I am interested in employing novel research methods to optimize care delivery for patients with inflammatory bowel disease. Specifically, my research uses machine learning and prediction modeling, adaptive interventions, and innovative clinical trial designs to develop evidence-based, patient-tailored treatment pathways for patients with acute severe ulcerative colitis. My broader goal is to improve treatment selection, identify patients at risk for poor outcomes earlier in their disease course, and translate evidence into scalable clinical care pathways.

    Recent Publications

    See All Publications
    • Presentation
      Inflammatory Bowel Disease Therapy Optimization
      Berinstein J. 2026 Sep 18;
    • Presentation
      The Clock Is Ticking: Optimal Strategies to Reduce Colectomy in the Hospitalized Patient With Acute Severe Ulcerative Colitis
      Berinstein J. 2026 Jul 16;
    • Presentation
      Inpatient IBD Management
      Berinstein J. 2026 Jul 16;
    • Presentation
      Acute Severe Ulcerative Colitis: 6 Fundamental Principals to Lower Colectomy
      Berinstein J. 2026 Jul 16;
    • Presentation
      Endoscopic Evaluation and Treatment of IBD
      Berinstein J. 2026 Jul 16;
    • Journal Article
      Rethinking the dose: A Bayesian meta-analysis of infliximab intensification in acute severe ulcerative colitis.
      Goyal MK, Dutta P, Choy MC, Berinstein JA, Hassan SA, Sharma V, Ahuja V, Berinstein E, Li Wai Suen CFD, Higgins PDR, Con D, Cruz PD, Bishu S. Inflamm Bowel Dis, 2026 Jul 1; 32 (7): 1344 - 1353. DOI:10.1093/ibd/izag042
      PMID: 42030468
    • Journal Article
      Navigating Treatment Selection in Acute Severe Ulcerative Colitis: A Prospective Mixed Method Analysis of Factors Influencing Patient Decision-Making.
      Herran R, Wilcox S, Hodish G, Hassan SA, Mertens H, Almario CV, Gu P, Kayal M, Cohen-Mekelburg S, Regal RE, Bishu S, Siegel CA, DeJonckheere M, Higgins PDR, Berinstein JA. Dig Dis Sci, 2026 Jun 24; DOI:10.1007/s10620-026-10046-0
      PMID: 42340521
    • Journal Article
      Clinical significance of isolated periappendiceal red patch in ulcerative colitis: A systematic review, meta-analysis, and meta-regression.
      Abdul Rehman K, Us Sehar N, Akram U, Fatima E, Ahsan S, Ahmed SZ, Faizan A, Javid S, Hassan SA, Berinstein JA, Barrett TA. Inflamm Bowel Dis, 2026 Jun 9; DOI:10.1093/ibd/izag092
      PMID: 42262727

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