Juilee Rege

 Juilee Rege
Research Assistant Professor, Molecular and Integrative Physiology
Adjunct Lecturer in Molecular and Integrative Physiology, Medical School
University of Michigan
Molecular & Integrative Physiology
1150 W Medical Center Drive, 2560 MSRB II
Ann Arbor, MI 48109
[email protected]
Available to mentor
Juilee Rege
Juilee Rege
Research Assistant Professor
  • Qualifications
  • Research Overview
  • Recent Publications

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    • Qualifications
    • Postdoctoral Research Fellow
      University of Michigan, Molecular & Integrative Physiology, Ann Arbor, United States
      2014 - 2018
      Postdoctoral Fellowship
    • PhD
      Department of Physiology, Medical College of Georgia/Georgia Regents University, Augusta, GA, United States
      2008 - 2014
    • MS
      University of Pune, Pune, India
      2005 - 2007
    • BSc
      University of Pune, Pune, India
      2002 - 2005

    Research Overview

    - Physiology and pathophysiology of adrenal aldosterone and cortisol production
    - Elucidation of the genetic and molecular mechanisms underlying adrenocortical tumors (aldosterone-producing adenomas and cortisol-producing adenomas)
    - Analysis of the steroid metabolome in physiology and adrenal-related pathologies using LC-MS/MS as a tool

    Recent Publications

     See All Publications
    • Journal Article
      Somatic SLC30A1 mutations altering zinc transporter ZnT1 cause aldosterone-producing adenomas and primary aldosteronism.
      Rege J, Bandulik S, Nanba K, Kosmann C, Blinder AR, Plain A, Vats P, Kumar-Sinha C, Lerario AM, Else T, Yamazaki Y, Satoh F, Sasano H, Giordano TJ, Williams TA, Reincke M, Turcu AF, Udager AM, Warth R, Rainey WE. Nat Genet, 2025 Jul 16; 55 (10): 1623 - 1631. DOI:10.1038/s41588-023-01498-5
    • Journal Article
      Targeted Mutational Analysis of Cortisol-Producing Adenomas
      Rege J, Hoxie J, Liu CJ, Cash MN, Luther JM, Gellert L, Turcu AF, Else T, Giordano TJ, Udager AM, Rainey WE, Nanba K. Journal of Clinical Endocrinology and Metabolism, 2022 Feb 1; 107 (2): E594 - E603. DOI:10.1210/clinem/dgab682
      PMID: 34534321
    • Journal Article
      Intratumoral steroid profiling of adrenal cortisol-producing adenomas by liquid chromatography- mass spectrometry
      Teuber JP, Nanba K, Turcu AF, Chen X, Zhao L, Else T, Auchus RJ, Rainey WE, Rege J. Journal of Steroid Biochemistry and Molecular Biology, 2021 Sep 1; 212: DOI:10.1016/j.jsbmb.2021.105924
      PMID: 34089832
    • Journal Article
      11-Oxygenated androgens in health and disease
      Turcu AF, Rege J, Auchus RJ, Rainey WE. Nature Reviews Endocrinology, 2020 May 1; 16 (5): 284 - 296. DOI:10.1038/s41574-020-0336-x
      PMID: 32203405
    • Journal Article
      Circulating 11-oxygenated androgens across species
      Rege J, Garber S, Conley AJ, Elsey RM, Turcu AF, Auchus RJ, Rainey WE. Journal of Steroid Biochemistry and Molecular Biology, 2019 Jun 1; 190: 242 - 249. DOI:10.1016/j.jsbmb.2019.04.005
      PMID: 30959151
    • Journal Article
      11-Ketotestosterone Is the Dominant Circulating Bioactive Androgen During Normal and Premature Adrenarche
      Rege J, Turcu AF, Kasa-Vubu JZ, Lerario AM, Auchus GC, Auchus RJ, Smith JM, White PC, Rainey WE. Journal of Clinical Endocrinology and Metabolism, 2018 Dec 1; 103 (12): 4589 - 4598.
    • Additional Scholarship
      Data from β-Catenin–Driven Differentiation Is a Tissue-Specific Epigenetic Vulnerability in Adrenal Cancer
      Mohan DR, Borges KS, Finco I, LaPensee CR, Rege J, Solon AL, Little DW, Else T, Almeida MQ, Dang D, Haggerty-Skeans J, Apfelbaum AA, Vinco M, Wakamatsu A, Mariani BMP, Amorim LC, Latronico AC, Mendonca BB, Zerbini MCN, Lawlor ER, Ohi R, Auchus RJ, Rainey WE, Marie SKN, Giordano TJ, Venneti S, Fragoso MCBV, Breault DT, Lerario AM, Hammer GD. 2025 Nov 24; DOI:10.1158/0008-5472.c.6711185
    • Journal Article
      Molecular characterization of archival adrenal tumor tissue from patients with ACTH-independent Cushing syndrome.
      Rege J, Udager AM. J Steroid Biochem Mol Biol, 2025 May 10; 247: 106666 - 106666. DOI:10.1016/j.jsbmb.2024.106666