Naheed W Khan
Ophthalmology & Visual Science
1000 Wall Street
Ann Arbor, MI 48105
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Qualifications
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Postdoctoral FellowColumbus Children's Hospital, Ophthalmology, Columbus, OH, USA
1988 - 1992
Postdoctoral Fellowship
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PhDThe Ohio State University, Columbus, OH, United States
1982 - 1988
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MSThe Ohio State University, Columbus, OH, United States
1980 - 1982
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BE, Electronics EngineeringBangalore University, Bengaluru, India
1974 - 1979
Center Memberships
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Center MemberCenter for Global Health Equity
Research Overview
Human retinal degenerative diseases. Use of electrophysiological and psychophysical tests to
characterize the clinical physiology and phenotype of inherited and acquired retinal disorders; diagnosis and
follow up of course of progression, electrophysiological assessment of therapies, clinical trials.
Animal models of human retinal degenerative diseases. Functional assessment of retinal function using
electrophysiological techniques in mice, evaluation of experimental treatments for human degenerative
diseases. Assessment of retinal function and rescue in mice that have received treatment like gene therapy,
collaborative efforts in translational research. Development and refinement of techniques to relate function
with pathology.
Recent Publications
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Lee Y, Gao Y, Nguyen VP, Liang B, Prieskorn DM, Beyer L, Wei Z, Khan N, Weiland J, Iannuzzi M, Bisgaier C, Raphael Y, Chen YE, Paulus YM, Yang D. Investigative Ophthalmology and Visual Science, 2026 Jul 1; 67 (8):Journal ArticleMüller Glia–Exclusive CLRN1 Expression Drives Non–Cell-Autonomous Photoreceptor Degeneration in Usher Syndrome Type 3A
DOI:10.1167/iovs.67.8.9 -
Parekh BJ, Stein JD, Abuzaitoun R, Andrews CA, Branham K, Milentijevic D, Narayanan D, Khan NW, Pershing S, Wang SY, Ahmad BU, Connor TB, Patnaik JL, Mathias M, Leys M, McMillan B, Amakiri N, Johnson TJ, Sun CQ, Duncan JL, Jayasundera KT, SOURCE consortium . Clin Exp Ophthalmol, 2026 Feb 27;Journal ArticleDecline of Visual Function and Risk of Legal Blindness With Age in RPGR-Associated Retinal Degeneration: A Multicenter Study.
DOI:10.1111/ceo.70093 PMID: 41760091 -
Thompson DA, Jayasundera KT, Alekseev O, Ali RR, Amato A, Arshavsky VY, Audo IS, Auricchio A, Bainbridge JWB, Banin E, Besirli CG, Birch DG, Branham KE, Cideciyan AV, Daiger SP, Duncan JL, Fahim A, Flannery JG, Gattegna R, Heckenlively JR, Héon E, Iannaccone A, Khan NW, Khateb S, Klassen HJ, Leroy BP, Marangoni D, Michaelides M, Musch DC, Pennesi ME, Petersen-Jones SM, Pierce EA, Rao RC, Sahel J-A, Sieving PA, Strettoi E, Strong CR, Wubben TJ, Yang P, Zacks DN. Translational Vision Science & Technology, 2025 Aug 27; 14 (8): 37 - 37.Journal ArticleAddressing Challenges in Developing Treatments for Inherited Retinal Diseases: Recommendations From the Third Monaciano Symposium
DOI:10.1167/tvst.14.8.37 -
Duncan JL, Maguire MG, McDaniel LS, Doucet NR, Audo I, Ayala AR, Cheetham JK, Cheng P, Durham TA, Huckfeldt RM, Hufnagel RB, Jayasundera KT, Khan N, Malbin B, Maldonado RS, Michaelides M, Pennesi ME, Weng CY, Zmejkoski A, Aravind S, Ishikawa H, Birch DG. American Journal of Ophthalmology, 2025 Aug 1; 276: 9 - 21.Journal ArticleCharacterization of Visual Field Loss Over 4 Years in the Rate of Progression in USH2A-Related Retinal Degeneration (RUSH2A) Study
DOI:10.1016/j.ajo.2025.03.039 PMID: 40157442 -
Biswas P, Woodard DNR, Hollingsworth TJ, Khan NW, Lazaro DR, Berry AM, Dagar M, Pan Y, Garland D, Shaw PX, Oka C, Iwata T, Jablonski MM, Ayyagari R. Jci Insight, 2025 Feb 10; 10 (3):Journal ArticleAblation of Htra1 leads to sub-RPE deposits and photoreceptor abnormalities
DOI:10.1172/jci.insight.178827 PMID: 39927462 -
Delaney A, Branham KE, Jayasundera KT, Khan NW, Fahim AT. Case Rep Ophthalmol, 2025 Sep 8; 16 (1): 395 - 405.Journal ArticleFemale Simplex Carriers of X-Linked Retinal Dystrophies: A Case Series.
DOI:10.1159/000546129 -
Abuzaitoun RO, Branham KH, Lacy GD, Hufnagel RB, Kumar MM, Koskenvuo JW, Tuupanen S, Durham T, Zhao PY, Abalem MF, Andrews CA, Schlegel D, Khan NW, Fahim AT, Heckenlively JR, Musch DC, Jayasundera KT. JAMA Ophthalmology, 2024 Dec 19; 142 (12): 1150 - 1156.Journal ArticleRacial Disparities in Genetic Detection Rates for Inherited Retinal Diseases
DOI:10.1001/jamaophthalmol.2024.4696 PMID: 39509105 -
Khan N. 2025 Jul 23;PresentationA Case of Two Causes of Night Blindness