1000 Wall Street
Ann Arbor, MI 48105
Available to mentor
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PhDThe Ohio State University, Columbus, 1988
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MSThe Ohio State University, Columbus, 1982
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BEBangalore University, Bengaluru, 1979
Human retinal degenerative diseases. Use of electrophysiological and psychophysical tests to
characterize the clinical physiology and phenotype of inherited and acquired retinal disorders; diagnosis and
follow up of course of progression, electrophysiological assessment of therapies, clinical trials.
Animal models of human retinal degenerative diseases. Functional assessment of retinal function using
electrophysiological techniques in mice, evaluation of experimental treatments for human degenerative
diseases. Assessment of retinal function and rescue in mice that have received treatment like gene therapy,
collaborative efforts in translational research. Development and refinement of techniques to relate function
with pathology.
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Feathers KL, Jia L, Khan NW, Smith AJ, Ma J-X, Ali RR, Thompson DA. Hum Gene Ther, 2023 Jul; 34 (13-14): 639 - 648.Journal ArticleGene Supplementation in Mice Heterozygous for the D477G RPE65 Variant Implicated in Autosomal Dominant Retinitis Pigmentosa.
DOI:10.1089/hum.2022.240 PMID: 37014074 -
Nguyen VP, Song J, Prieskorn D, Zou J, Li Y, Dolan D, Xu J, Zhang J, Jayasundera KT, Yang J, Raphael Y, Khan N, Iannuzzi M, Bisgaier C, Chen YE, Paulus YM, Yang D. Transl Vis Sci Technol, 2023 Feb 1; 12 (2): 26Journal ArticleUSH2A Gene Mutations in Rabbits Lead to Progressive Retinal Degeneration and Hearing Loss.
DOI:10.1167/tvst.12.2.26 PMID: 36795064 -
Biswas P, Berry AM, Zawaydeh Q, Bartsch D-UG, Raghavendra PB, Hejtmancik JF, Khan NW, Riazuddin SA, Ayyagari R. Genes (Basel), 2022 Aug 17; 13 (8):Journal ArticleA Mouse Model with Ablated Asparaginase and Isoaspartyl Peptidase 1 (Asrgl1) Develops Early Onset Retinal Degeneration (RD) Recapitulating the Human Phenotype.
DOI:10.3390/genes13081461 PMID: 36011372 -
Deng C, Zhao PY, Branham K, Schlegel D, Fahim AT, Jayasundera TK, Khan N, Besirli CG. Graefes Arch Clin Exp Ophthalmol, 2022 May; 260 (5): 1543 - 1550.Journal ArticleReal-world outcomes of voretigene neparvovec treatment in pediatric patients with RPE65-associated Leber congenital amaurosis.
DOI:10.1007/s00417-021-05508-2 PMID: 35001204 -
Xu G, Khan N, Almazroa A, Pawar M, Besirli C, Paulus YM, Wang X, Demirci H. Transl Vis Sci Technol, 2022 Mar 2; 11 (3): 30Journal ArticleSafety Evaluation of Photoacoustic Tomography System for Intraocular Tumors.
DOI:10.1167/tvst.11.3.30 PMID: 35344017 -
Toulis V, Casaroli-Marano R, Camós-Carreras A, Figueras-Roca M, Sánchez-Dalmau B, Muñoz E, Ashraf NS, Ferreira AF, Khan N, Marfany G, Costa MDC. Neurobiol Dis, 2022 Aug; 170: 105774Journal ArticleAltered retinal structure and function in Spinocerebellar ataxia type 3.
DOI:10.1016/j.nbd.2022.105774 PMID: 35605759 -
Toulis V, Casaroli-Marano R, Camós-Carreras A, Figueras-Roca M, Sánchez-Dalmau B, Muñoz E, Ashraf NS, Ferreira AF, Khan N, Marfany G, Costa MDC. Neurobiology of disease, 2022 Jan 21; 170:Journal ArticleAltered retinal structure and function in Spinocerebellar ataxia type 3.
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Khan M, Branham K, Jayasundera KT, Khan NW. Ophthalmic genetics, 2022 Jan 16; 1 - 8.Journal ArticleAdherence and satisfaction in Argus II prosthesis users: a self determination theory model.
