Available to mentor
Robert Kennedy is a Professor of Chemistry and Pharmacology. His research interests are in bioanalytical chemistry with an emphasis on microfluidics, mass spectrometry, chromatography, and electrophoresis. He develops these methods to study neurotransmitter dynamics in vivo, hormone secretion, and for high-throughput experimentation.
My Background
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PhDUniversity of North Carolina-Chapel Hill, United States, 1988
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Center MemberCaswell Diabetes Institute
We develop and apply bioanalytical methods for studying hormone and neurtransmitter secretion. We develop microfluidic chips to culture cells and integrate methods to measure releasate. We also coupling sampling probes to analytical methods for in vivo brain chemical measurements. We develop metabolomics methods for studying biological systems. We have focused LC-MS/MS, capillary electrophoresis, and sensors for analysis. We have applied to study of islets of Langerhans and various rodent models in the brain.
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Anderson BG, Raskind A, Hissong R, Dougherty MK, McGill SK, Gulati AS, Theriot CM, Kennedy RT, Evans CR. J Proteome Res, 2024 Jun 7; 23 (6): 2000 - 2012.Journal ArticleOffline Two-Dimensional Liquid Chromatography-Mass Spectrometry for Deep Annotation of the Fecal Metabolome Following Fecal Microbiota Transplantation.
DOI:10.1021/acs.jproteome.4c00022 PMID: 38752739 -
Anderson BG, Hancock TA, Kennedy RT. J Chromatogr A, 2024 May 10; 1722: 464856Journal ArticlePreparation of high-efficiency HILIC capillary columns utilizing slurry packing at 2100 bar.
DOI:10.1016/j.chroma.2024.464856 PMID: 38579610 -
Lenhart AE, Booth P-PM, Simcox KM, Ramos BA, Kennedy RT. J Chromatogr A, 2024 May 10; 1722: 464872Journal ArticleSystematic evaluation of benzoylation for liquid chromatography-mass spectrometry analysis of different analyte classes.
DOI:10.1016/j.chroma.2024.464872 PMID: 38581975 -
Glynos NG, Huels ER, Nelson A, Kim Y, Kennedy RT, Mashour GA, Pal D. 2024 Apr 22;PreprintNeurochemical and Neurophysiological Effects of Intravenous Administration of N,N-dimethyltryptamine in Rats.
DOI:10.1101/2024.04.19.589047 PMID: 38712161 -
Makey DM, Gadkari VV, Kennedy RT, Ruotolo BT. Anal Chem, 2024 Apr 16; 96 (15): 6021 - 6029.Journal ArticleCyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers.
DOI:10.1021/acs.analchem.4c00477 PMID: 38557001 -
Xin Y, Foster SW, Makey DM, Parker D, Bradow J, Wang X, Berritt S, Mongillo R, Grinias JP, Kennedy RT. Anal Chem, 2024 Mar 19; 96 (11): 4693 - 4701.Journal ArticleHigh-Throughput Capillary Liquid Chromatography Using a Droplet Injection and Application to Reaction Screening.
DOI:10.1021/acs.analchem.4c00150 PMID: 38442211 -
Wells SS, Bain IJ, Valenta AC, Lenhart AE, Steyer DJ, Kennedy RT. Analyst, 2024 Apr 15; 149 (8): 2328 - 2337.Journal ArticleMicrodialysis coupled with droplet microfluidics and mass spectrometry for determination of neurotransmitters in vivo with high temporal resolution.
DOI:10.1039/d4an00112e PMID: 38488040 -
Makey D, Gadkari V, Kennedy R, Ruotolo B. ChemRxiv,PreprintCyclic Ion Mobility-Mass Spectrometry and Tandem Collision Induced Unfolding for Quantification of Elusive Protein Biomarkers
DOI:10.26434/chemrxiv-2024-4j998