Meredith A Morgan
Theodore S Lawrence M.D.
Ph.D. and Patricia Krause Research Professor of Radiation Oncology
Associate Chair, Department of Radiation and Cancer Biology
Department of Radiation Oncology and Professor of Radiation Oncology
Radiation Oncology
1301 Catherine Street
Ann Arbor, Michigan 48109 SPC 5637
[email protected]

Available to mentor
Meredith A Morgan
Professor
  • About
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
    • About

    Dr. Morgan leads a laboratory focused on improving standard radiation and chemoradiation therapies through the use of novel agents targeting DNA damage response and repair. Her research program prioritizes pre-clinical research with strong clinical/translational relevance with an emphasis on pancreatic cancer. More specific areas of research interest include DNA double-strand break repair, DNA replication, cell cycle and biomarker development.

    Qualifications
    • Research Fellow
      University of Michigan, United States, 2005
    • Postdoctoral Research Fellow
      West Virginia University, United States, 2002
    Center Memberships
    • Center Member
      Rogel Cancer Center
    Research Overview

    DNA damage response inhibitors
    Radio - and chemo- sensitization
    DNA repair and DNA replication stress
    Immunotherapy and tumor immunology
    Translational research
    Pancreatic cancer and diffuse intrinsic pontine glioma

    Recent Publications See All Publications
    • Journal Article
      SLC4A11 mediates ammonia import and promotes cancer stemness in hepatocellular carcinoma.
      Elaimy AL, El-Derany MO, James J, Wang Z, Pearson AN, Holcomb EA, Huber AK, Gijón M, Bell HN, Sanghvi VR, Frankel TL, Su GL, Tapper EB, Tai AW, Ramnath N, Centonze CP, Dobrosotskaya I, Moeller JA, Bryant AK, Elliott DA, Choi E, Evans JR, Cuneo KC, Fitzgerald TJ, Wahl DR, Morgan MA, Chang DT, Wicha MS, Lawrence TS, Shah YM, Green MD. JCI Insight, 2024 Nov 8; 9 (21): DOI:10.1172/jci.insight.184826
      PMID: 39287988
    • Preprint
      Inhibition of H3K27M-enhanced ATM signaling increases radiation efficacy in diffuse midline glioma
      Peterson E, Parsels LA, Parsels JD, Zhao X, Castro MG, Lawrence TS, Koschmann C, Zhang Q, Wahl DR, Morgan MA. bioRxiv, DOI:10.1101/2024.11.01.621526
    • Preprint
      H3K27M diffuse midline glioma is homologous recombination defective and sensitized to radiotherapy and NK cell-mediated antitumor immunity by PARP inhibition.
      Guo Y, Li Z, Parsels LA, Wang Z, Parsels JD, Dalvi A, The S, Hu N, Valvo VM, Doherty R, Peterson E, Wang X, Venkataraman S, Agnihotri S, Venneti S, Wahl DR, Green MD, Lawrence TS, Koschmann C, Morgan MA, Zhang Q. 2024 Aug 27; DOI:10.1101/2024.08.26.609803
      PMID: 39253432
    • Journal Article
      Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma.
      Peterson ER, Sajjakulnukit P, Scott AJ, Heaslip C, Andren A, Wilder-Romans K, Zhou W, Palavalasa S, Korimerla N, Lin A, O'Brien A, Kothari A, Zhao Z, Zhang L, Morgan MA, Venneti S, Koschmann C, Jabado N, Lyssiotis CA, Castro MG, Wahl DR. Cancer Metab, 2024 Apr 9; 12 (1): 11 DOI:10.1186/s40170-024-00341-7
      PMID: 38594734
    • Additional Scholarship
      Data from GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress
      Zhou W, Zhao Z, Lin A, Yang JZ, Xu J, Wilder-Romans K, Yang A, Li J, Solanki S, Speth JM, Walker N, Scott AJ, Wang L, Wen B, Andren A, Zhang L, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Ullrich A, Liang J, Jacobson J, Palavalasa S, O’Brien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Győrffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. 2024 Jan 12; DOI:10.1158/2159-8290.c.7022618.v1
    • Additional Scholarship
      Data from GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress
      Zhou W, Zhao Z, Lin A, Yang JZ, Xu J, Wilder-Romans K, Yang A, Li J, Solanki S, Speth JM, Walker N, Scott AJ, Wang L, Wen B, Andren A, Zhang L, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Ullrich A, Liang J, Jacobson J, Palavalasa S, O’Brien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Győrffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. 2024 Jan 12; DOI:10.1158/2159-8290.c.7022618
    • Additional Scholarship
      Supplementary Data 1 from GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress
      Zhou W, Zhao Z, Lin A, Yang JZ, Xu J, Wilder-Romans K, Yang A, Li J, Solanki S, Speth JM, Walker N, Scott AJ, Wang L, Wen B, Andren A, Zhang L, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Ullrich A, Liang J, Jacobson J, Palavalasa S, O’Brien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Győrffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. 2024 Jan 12; DOI:10.1158/2159-8290.24988568.v1
    • Additional Scholarship
      Supplementary Data 1 from GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress
      Zhou W, Zhao Z, Lin A, Yang JZ, Xu J, Wilder-Romans K, Yang A, Li J, Solanki S, Speth JM, Walker N, Scott AJ, Wang L, Wen B, Andren A, Zhang L, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Ullrich A, Liang J, Jacobson J, Palavalasa S, O’Brien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Győrffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. 2024 Jan 12; DOI:10.1158/2159-8290.24988568