Professor Emerita of Anesthesiology
[email protected]
Available to mentor
Lucy Waskell
Professor Emeritus/a
-
Rwere F, Cartee NMP, Yang Y, Waskell L. J Inorg Biochem, 2024 Oct; 259: 112667Journal ArticleA flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity.
DOI:10.1016/j.jinorgbio.2024.112667 PMID: 39032346 -
Rwere F, Im S, Waskell L. Int J Mol Sci, 2021 Sep 30; 22 (19):Journal ArticleThe FMN "140s Loop" of Cytochrome P450 Reductase Controls Electron Transfer to Cytochrome P450.
DOI:10.3390/ijms221910625 PMID: 34638963 -
Bai J, Wang J, Ravula T, Im S-C, Anantharamaiah GM, Waskell L, Ramamoorthy A. Biochim Biophys Acta Biomembr, 2020 May 1; 1862 (5): 183194Journal ArticleExpression, purification, and functional reconstitution of 19F-labeled cytochrome b5 in peptide nanodiscs for NMR studies.
DOI:10.1016/j.bbamem.2020.183194 PMID: 31953231 -
Yang Y, Bu W, Im S, Meagher J, Stuckey J, Waskell L. J Inorg Biochem, 2018 Aug; 185: 17 - 25.Journal ArticleStructure of cytochrome P450 2B4 with an acetate ligand and an active site hydrogen bond network similar to oxyferrous P450cam.
DOI:10.1016/j.jinorgbio.2018.04.015 PMID: 29730233 -
Prade E, Mahajan M, Im S-C, Zhang M, Gentry KA, Anantharamaiah GM, Waskell L, Ramamoorthy A. Angew Chem Int Ed Engl, 2018 Jul 9; 57 (28): 8458 - 8462.Journal ArticleA Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs.
DOI:10.1002/anie.201802210 PMID: 29722926 -
Barnaba C, Sahoo BR, Ravula T, Medina-Meza IG, Im S-C, Anantharamaiah GM, Waskell L, Ramamoorthy A. Angew Chem Int Ed Engl, 2018 Mar 19; 57 (13): 3391 - 3395.Journal ArticleCytochrome-P450-Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs.
DOI:10.1002/anie.201713167 PMID: 29385304 -
Xia C, Rwere F, Im S, Shen AL, Waskell L, Kim J-JP. Biochemistry, 2018 Feb 13; 57 (6): 945 - 962.Journal ArticleStructural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer.
DOI:10.1021/acs.biochem.7b01102 PMID: 29308883 -
Ravula T, Hardin NZ, Bai J, Im S-C, Waskell L, Ramamoorthy A. Chem Commun (Camb), 2018 Aug 23; 54 (69): 9615 - 9618.Journal ArticleEffect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs.
DOI:10.1039/c8cc04184a PMID: 30094448
