Lucy Waskell
Professor Emerita of Anesthesiology
Medical School
[email protected]
Available to mentor
Lucy Waskell
Professor Emeritus/a
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Recent Publications
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Rwere F, Cartee NMP, Yang Y, Waskell L. Journal of Inorganic Biochemistry, 2024 Oct 1; 259:Journal ArticleA flexible linker of 8-amino acids between the membrane binding segment and the FMN domain of cytochrome P450 reductase is necessary for optimal activity
DOI:10.1016/j.jinorgbio.2024.112667 PMID: 39032346 -
Rwere F, Im S, Waskell L. International Journal of Molecular Sciences, 2021 Oct 1; 22 (19):Journal ArticleThe fmn “140s loop” of cytochrome p450 reductase controls electron transfer to cytochrome p450
DOI:10.3390/ijms221910625 PMID: 34638963 -
Bai J, Wang J, Ravula T, Im SC, Anantharamaiah GM, Waskell L, Ramamoorthy A. Biochimica et Biophysica Acta - Biomembranes, 2020 May 1; 1862 (5):Journal ArticleExpression, purification, and functional reconstitution of <sup>19</sup>F-labeled cytochrome b5 in peptide nanodiscs for NMR studies
DOI:10.1016/j.bbamem.2020.183194 PMID: 31953231 -
Yang Y, Bu W, Im S, Meagher J, Stuckey J, Waskell L. Journal of Inorganic Biochemistry, 2018 Aug 1; 185: 17 - 25.Journal ArticleStructure of cytochrome P450 2B4 with an acetate ligand and an active site hydrogen bond network similar to oxyferrous P450cam
DOI:10.1016/j.jinorgbio.2018.04.015 PMID: 29730233 -
Prade E, Mahajan M, Im SC, Zhang M, Gentry KA, Anantharamaiah GM, Waskell L, Ramamoorthy A. Angewandte Chemie - International Edition, 2018 Jul 9; 57 (28): 8458 - 8462.Journal ArticleA Minimal Functional Complex of Cytochrome P450 and FBD of Cytochrome P450 Reductase in Nanodiscs
DOI:10.1002/anie.201802210 PMID: 29722926 -
Barnaba C, Sahoo BR, Ravula T, Medina-Meza IG, Im SC, Anantharamaiah GM, Waskell L, Ramamoorthy A. Angewandte Chemie - International Edition, 2018 Mar 19; 57 (13): 3391 - 3395.Journal ArticleCytochrome-P450-Induced Ordering of Microsomal Membranes Modulates Affinity for Drugs
DOI:10.1002/anie.201713167 PMID: 29385304 -
Xia C, Rwere F, Im S, Shen AL, Waskell L, Kim JJP. Biochemistry, 2018 Feb 13; 57 (6): 945 - 962.Journal ArticleStructural and Kinetic Studies of Asp632 Mutants and Fully Reduced NADPH-Cytochrome P450 Oxidoreductase Define the Role of Asp632 Loop Dynamics in the Control of NADPH Binding and Hydride Transfer
DOI:10.1021/acs.biochem.7b01102 PMID: 29308883 -
Ravula T, Hardin NZ, Bai J, Im SC, Waskell L, Ramamoorthy A. Chem Commun (Camb), 2018 Jan 1; published ahead:Journal ArticleEffect of polymer charge on functional reconstitution of membrane proteins in polymer nanodiscs.
