Cagri G Besirli, MD, PhD

 Cagri G. Besirli
Skillman Foundation Research Professor of Pediatric Ophthalmology
Associate Professor of Ophthalmology and Visual Sciences
Medical School
University of Michigan
Ophthalmology and Visual Sciences
1000 Wall Street
Ann Arbor, MI 48105
[email protected]
Available to mentor
Cagri G Besirli, MD, PhD
Cagri G. Besirli
Associate Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications

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    • Qualifications
    • Clinical Lecturer/Fellow
      University of Michigan, Ophthalmology and Visual Sciences, Ann Arbor, United State
      2010 - 2012
      Clinical Fellowship
    • Pediatric Vitreoretinal Surgery
      Associated Retinal Consultants, Royal Oak, United States
      2012 - 2012
      Other
    • Resident
      University of Michigan, Ophthalmology, Ann Arbor, United States
      2007 - 2010
      Chief Resident
    • Chief Resident
      University of Michigan, Ophthalmology, United States
      2009 - 2010
      Chief Resident
    • Resident
      Saint Joseph Mercy Health System, Ann Arbor, United States
      2006 - 2007
      Residency

    Center Memberships
    • Center Member
      Biosciences Initiative
    • Center Member
      Weil Institute for Critical Care Research

    Research Overview

    - Molecular mechanisms of photoreceptor cell death
    - Retinal metabolism
    - Gene therapy for retinal degeneration
    - Ocular toxicity of systemic medications
    - Retinopathy of prematurity screening and diagnosis
    - Telemedicine applications in ophthalmic diseases
    - Medical device and drug delivery development

    Links
    • https://www.uofmhealth.org/profile/1154443497/cagri-giray-besirli

    Recent Publications

     See All Publications
    • Journal Article
      Interim Results From a Multicenter Observational Safety Study of Patients Treated With Voretigene Neparvovec-rzyl in the United States
      Nagiel A, Russell SR, Lam BL, Comander JI, Aleman TS, Besirli CG, Sisk RA, Yang P, Weng CY, Chung DC, Thakre A, Savola J-M, Rousso DL, Weng C, Stout T, Scholle T, Nagiel A, Borchert M, Schwartz H, Lee T, Sisk R, Riemann C, Comander J, Yang P, Bailey S, Everett L, Lauer A, Pennesi M, Aleman TS, Maguire AM, Russell S, Drack A, Dumitrescu A, Han I, Larson S, Sohn E, Lam B, Berrocal A, Davis J, Gregori N, Mendoza-Santiesteban C, Townsend J, Besirli C, Branham K, Fahim A, Jayasundera K, Khan N. Ophthalmology, 2026 Jul 23; DOI:10.1016/j.ophtha.2026.07.007
    • Journal Article
      High-Density Lipoprotein Nanoparticles Delivering Liver X Receptor Agonist for the Treatment of Age-Related Macular Degeneration.
      Mei L, Weh E, Yu M, Walsh L, Fahim AT, Liu Y, Besirli CG, Schwendeman A. Mol Pharm, 2026 May 22; DOI:10.1021/acs.molpharmaceut.5c01852
      PMID: 42172633
    • Preprint
      Racial and ethnic representation in retinopathy of prematurity related clinical trials from 1995 to 2023
      Daniel Y, Lyu X, Besirli CG, Eton EA. 2026 May 23; Research Square, DOI:10.21203/rs.3.rs-9673009/v1
    • Journal Article
      Multi-grader validation of the telemedicine retinopathy of prematurity severity score.
      Pratt HW, Shah SV, Zhao CS, Brant AR, Baumal CR, Besirli CG, Berrocal AM, Drenser KA, Ells AL, Harper CA, Hubbard GB, Nudleman ED, Quiram P, Tsui I, Wood E, Yonekawa Y, Rosenblatt T, Kumm J, Moshfeghi DM. Sci Rep, 2026 May 12; DOI:10.1038/s41598-026-51824-0
      PMID: 42120460
    • Journal Article
      Comparing Rhegmatogenous and Tractional Retinal Detachment in Regressed Retinopathy of Prematurity: An International, Multicenter Study
      HSU HANTUNG, KANG EYC, BLAIR MP, SHAPIRO M, KOMATI R, HUBBARD BG, PRICE KW, CAPONE A, DRENSER KA, TRESE MGJ, SHIELDS RYAN, KONDO H, MATSUSHITA I, YONEKAWA Y, PATEL SN, KUSAKA S, MANO F, OLSEN KR, ELLS ANNA, AMPHORNPHRUET A, WALSH MK, BESIRLI CG, MOINUDDIN OMAR, BAUMAL CR, ENRIQUEZ AB, HWANG YIHSHIOU, LAI CHICHUN, HUANG PINHSUAN, WU WEICHI. American Journal of Ophthalmology, 2026 Feb 1; 282: 1 - 10. DOI:10.1016/j.ajo.2025.10.022
      PMID: 41135932
    • Journal Article
      Online Information on Retinopathy of Prematurity: A Comparative Study Across Academic and Non-academic Hospital Websites by Region
      Fleifil S, Parekh B, Purt B, Besirli C, Vartanian R, Valikodath N, Cole ED. Journal of Neonatology, 2026 Jan 1; DOI:10.1177/09732179261450848
    • Journal Article
      A Review of Retinopathy of Prematurity
      Fleifil S, Eton E, Besirli C, Valikodath N. Review of Ophthalmology, 2026 Jan 3;
    • Journal Article
      Incidence and Impact of Outer Retinal Folds After Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment Repair
      Eton EA, Pan WW, Besirli CG, Zacks DN, Wubben TJ. Journal of Vitreoretinal Diseases, 2025 Sep 1; 9 (5): 607 - 613. DOI:10.1177/24741264251350023