David N Zacks

 David N. Zacks
Edna H Perkiss Research Professor of Ophthalmology and Visual Sciences
Professor of Ophthalmology and Visual Sciences, Medical School
Email:
[email protected]
Available to mentor
David N Zacks
David N. Zacks
Professor
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    • Center Memberships
    • Center Member
      Global REACH
    • Center Member
      MM-PKUHSC Joint Institute
    • Center Member
      Caswell Diabetes Institute

    Recent Publications

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    • Journal Article
      Recovery from apoptosis in photoreceptor cells: A role for mitophagy
      Kaur B, Miglioranza Scavuzzi B, Yao J, Yang M, Jia L, Lentz SI, Sadda J, Kocab AJ, Shanmugam S, Zacks DN. Cell Death and Disease, 2026 Dec 1; 17 (1): DOI:10.1038/s41419-026-08436-3
      PMID: 41617676
    • Journal Article
      Intravitreal ONL1204 Ophthalmic Solution in Subjects With Macula-Off Rhegmatogenous Retinal Detachment.
      Kleinman DM, Wykoff CC, Borkar DS, Almeida DRP, Ho AC, Miller JW, Kocab AJ, Puscas L, Wietholter SC, Kesteloot LL, Zacks DN. J Vitreoretin Dis, 2026 Oct 17; 24741264261495492 DOI:10.1177/24741264261495492
      PMID: PMC13676687
    • Journal Article
      Time to Revisit the Endophthalmitis Vitrectomy Study: Areas for Improvement in the Diagnosis and Treatment of Endophthalmitis
      Conrady CD, Zacks DN. Ophthalmology, 2026 Jun 1; 133 (6): 697 - 699. DOI:10.1016/j.ophtha.2026.02.016
      PMID: 42167827
    • Journal Article
      Pathogen-Associated Visual Outcomes Following Postprocedure Endophthalmitis
      Ather M, Lyden E, Zhan Y, Haliyur R, Sinha A, Patel S, Feist RM, Shakoor A, Vitale AT, Zacks DN, Yeh S, Forest TEDC, Huvard MJ, Conrady CD. American Journal of Ophthalmology, 2026 Mar 1; 283: 72 - 80. DOI:10.1016/j.ajo.2025.11.038
      PMID: 41317830
    • Journal Article
      ONL1204 for the Treatment of Geographic Atrophy: Phase Ib Study Evaluating Safety, Tolerability, and Efficacy
      Kleinman DM, Wykoff CC, Borkar DS, Guymer RH, Kocab AJ, Puscas L, Wietholter SC, Kesteloot LL, Zacks DN. Ophthalmology Science, 2026 Jan 1; 6 (1): DOI:10.1016/j.xops.2025.100954
    • Journal Article
      Neuroprotection of photoreceptors by combined inhibition of both Fas and autophagy pathways in P23H mice
      Yang M, Yao J, Jia L, Kocab AJ, Zacks DN. Cell Death and Disease, 2025 Dec 1; 16 (1): DOI:10.1038/s41419-025-07793-9
      PMID: 40592891
    • Journal Article
      In Vivo Characterization of ONL1204, a Small Peptide Inhibitor of the Fas Receptor, as a Potential Neuroprotective Therapy for Geographic Atrophy and Dry Age-Related Macular Degeneration
      Kocab AJ, Cano M, Bacellar-Galdino M, Jamison JA, Brock WJ, Zacks DN, Handa JT. Biomedicines, 2025 Sep 1; 13 (9): DOI:10.3390/biomedicines13092052
    • Journal Article
      Incidence and Impact of Outer Retinal Folds After Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment Repair
      Eton EA, Pan WW, Besirli CG, Zacks DN, Wubben TJ. Journal of Vitreoretinal Diseases, 2025 Sep 1; 9 (5): 607 - 613. DOI:10.1177/24741264251350023

    Featured News & Stories

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    Health Lab

    Cell death in photoreceptor cells is reversible, study finds

    A team of researchers from the University of Michigan found functional mitochondria are key to the recovery of dying photoreceptor cells.