Elliot B Tapper, MD, FAASLD
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About
Elliot B. Tapper MD is a Professor in the Division of Gastroenterology and Hepatology. He is Academic Chief of Hepatology. His primary goal is to empower patients to enjoy a high quality of life. He is an expert in the management of chronic liver disease, performance of clinical trials, and big data for the study of liver disease. He has developed strategies that reduce symptoms and improve quality of life and invented tools that have helped keep patients with cirrhosis at home and away from the hospital. He is the Editor-in-Chief of Hepatology Communications.
Center Memberships
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Center MemberInstitute for Healthcare Policy and Innovation
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Center MemberAI and Digital Health Innovation
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Center MemberEisenberg Family Depression Center
Research Overview
1. Patient reported outcomes (PROs) and symptoms of cirrhosis: We seek to characterize the burden, determinants, and impact of poor health related quality of life and symptoms in cirrhosis. We conduct clinical trials that aim to alleviate these symptoms.
2. Frailty and sarcopenia: Prior work has focused on defining the burden and impact of frailty and sarcopenia, the relationship between hepatic encephalopathy and frailty, and the development of risk-assessment tools. Current research is focused on nutritional, behavioral, and pharmacological interventions to improve and prevent frailty.
3. Hepatic encephalopathy (HE): We aim to optimize risk stratification for overt HE and its complications with a focus on hospitalization and falls and to develop interventions to prevent HE.
4. Quality improvement: We utilize electronic interventions to standardize care, improve quality indicators, integrate patient reported outcomes in care delivery, and reduce patient harms.
Recent Publications
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2026 Sep 28;PresentationAcademic Debates
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Tapper EB, Asrani S, Weinberg E, Zhao L, Nikirk S, Mehta S, Alexander NB, Chen X, Evon DM, Serper M. Hepatology, 2026 Sep 16;Journal ArticleLactulose with or without TeleTai-Chi for the prevention of falls: A sequential multiple assignment randomized controlled trial (LiveSMART).
DOI:10.1097/HEP.0000000000001869 PMID: 42752551 -
Verma M, John BV, Rockey D, Barritt S, Navarro V, Shaw LK, Kosinski A, Tapper EB, Desai A. Hepatol Commun, 2026 Sep 1; 10 (9):Journal ArticleMeasuring quality of life in advanced chronic liver disease with FACT-Hep: Findings from the PAL LIVER trial.
DOI:10.1097/HC9.0000000000001043 PMID: PMC13533500 -
Kasmikha L, Chen X, Serper M, Tapper EB. Liver Int, 2026 Aug; 46 (8): e70765Journal ArticleSystematic Review and Meta-Analysis of Lactulose for the Prevention and Treatment of Hepatic Encephalopathy.
DOI:10.1111/liv.70765 PMID: 42402719 -
Niezen S, Kalligeros M, Mehta MKS, Tapper EB. Journal of Clinical and Experimental Hepatology, 2026 Jul 15; 103612Journal ArticleCoffee Consumption and Lower Advanced Fibrosis Risk in MASLD and MetALD: Dose-Dependent Association with Heightened Protection Among Moderate Alcohol Users
DOI:10.1016/j.jceh.2026.103612 -
Giri S, Panda S, Singh A, Varghese J, Ingawale S, Tapper EB, Rockey DC, Choudhury A. Hepatology Forum, 2026 Jul 1; 7 (3): 218 - 226.Journal ArticleDuration of vasoconstrictors after endoscopic variceal ligation in acute variceal bleeding: A systematic review and network meta-analysis
DOI:10.14744/hf.2025.82371 -
Tranah TH, Kronsten VT, Frolkis A, Seager M, Mangini C, Ntuli Y, Montagnese S, Shawcross DL, Tapper EB. Frontline Gastroenterology, 2026 Jul 1; 17 (4): 357 - 369.Journal ArticleHepatic encephalopathy: Part 3, outpatient management
DOI:10.1136/flgastro-2026-103734 -
Yoder L, Tapper EB, Kalman R, Rinella M, Bendin N, Verma M, Pike F, Chalasani N, Nalumasu N, Orman ES. Hepatol Commun, 2026 Jul 1; 10 (7):Journal ArticleThe Transitional Liver Clinic: Study protocol for a stepped-wedge cluster randomized trial.
DOI:10.1097/HC9.0000000000000990 PMID: PMC13286549
Featured News & Stories
Drug candidate treats severe fatty liver disease by protecting the gut in animal models
Managing cirrhosis pain without drugs
Lactulose and tai chi show promise preventing falls for cirrhosis patients
CME Event - 28th Annual Liver Disease Wrap-Up
Internal Medicine Faculty Spotlight − Dr. Elliot Tapper