Elliot B Tapper, MD, FAASLD

Elliot Tapper
Andrews Family Research Professor of Hepatology and Professor of Internal Medicine
Medical School
Email:
[email protected]
Available to mentor
Elliot B Tapper, MD, FAASLD
Elliot Tapper
Professor
  • About
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    Elliot B. Tapper MD is a Professor in the Division of Gastroenterology and Hepatology. He is Academic Chief of Hepatology. His primary goal is to empower patients to enjoy a high quality of life. He is an expert in the management of chronic liver disease, performance of clinical trials, and big data for the study of liver disease. He has developed strategies that reduce symptoms and improve quality of life and invented tools that have helped keep patients with cirrhosis at home and away from the hospital. He is the Editor-in-Chief of Hepatology Communications.

    Center Memberships

    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      AI and Digital Health Innovation
    • Center Member
      Eisenberg Family Depression Center

    Research Overview

    1. Patient reported outcomes (PROs) and symptoms of cirrhosis: We seek to characterize the burden, determinants, and impact of poor health related quality of life and symptoms in cirrhosis. We conduct clinical trials that aim to alleviate these symptoms.
    2. Frailty and sarcopenia: Prior work has focused on defining the burden and impact of frailty and sarcopenia, the relationship between hepatic encephalopathy and frailty, and the development of risk-assessment tools. Current research is focused on nutritional, behavioral, and pharmacological interventions to improve and prevent frailty.
    3. Hepatic encephalopathy (HE): We aim to optimize risk stratification for overt HE and its complications with a focus on hospitalization and falls and to develop interventions to prevent HE.
    4. Quality improvement: We utilize electronic interventions to standardize care, improve quality indicators, integrate patient reported outcomes in care delivery, and reduce patient harms.

    Recent Publications

    See All Publications
    • Presentation
      Academic Debates
      2026 Sep 28;
    • Journal Article
      Lactulose with or without TeleTai-Chi for the prevention of falls: A sequential multiple assignment randomized controlled trial (LiveSMART).
      Tapper EB, Asrani S, Weinberg E, Zhao L, Nikirk S, Mehta S, Alexander NB, Chen X, Evon DM, Serper M. Hepatology, 2026 Sep 16; DOI:10.1097/HEP.0000000000001869
      PMID: 42752551
    • Journal Article
      Measuring quality of life in advanced chronic liver disease with FACT-Hep: Findings from the PAL LIVER trial.
      Verma M, John BV, Rockey D, Barritt S, Navarro V, Shaw LK, Kosinski A, Tapper EB, Desai A. Hepatol Commun, 2026 Sep 1; 10 (9): DOI:10.1097/HC9.0000000000001043
      PMID: PMC13533500
    • Journal Article
      Systematic Review and Meta-Analysis of Lactulose for the Prevention and Treatment of Hepatic Encephalopathy.
      Kasmikha L, Chen X, Serper M, Tapper EB. Liver Int, 2026 Aug; 46 (8): e70765 DOI:10.1111/liv.70765
      PMID: 42402719
    • Journal Article
      Coffee Consumption and Lower Advanced Fibrosis Risk in MASLD and MetALD: Dose-Dependent Association with Heightened Protection Among Moderate Alcohol Users
      Niezen S, Kalligeros M, Mehta MKS, Tapper EB. Journal of Clinical and Experimental Hepatology, 2026 Jul 15; 103612 DOI:10.1016/j.jceh.2026.103612
    • Journal Article
      Duration of vasoconstrictors after endoscopic variceal ligation in acute variceal bleeding: A systematic review and network meta-analysis
      Giri S, Panda S, Singh A, Varghese J, Ingawale S, Tapper EB, Rockey DC, Choudhury A. Hepatology Forum, 2026 Jul 1; 7 (3): 218 - 226. DOI:10.14744/hf.2025.82371
    • Journal Article
      Hepatic encephalopathy: Part 3, outpatient management
      Tranah TH, Kronsten VT, Frolkis A, Seager M, Mangini C, Ntuli Y, Montagnese S, Shawcross DL, Tapper EB. Frontline Gastroenterology, 2026 Jul 1; 17 (4): 357 - 369. DOI:10.1136/flgastro-2026-103734
    • Journal Article
      The Transitional Liver Clinic: Study protocol for a stepped-wedge cluster randomized trial.
      Yoder L, Tapper EB, Kalman R, Rinella M, Bendin N, Verma M, Pike F, Chalasani N, Nalumasu N, Orman ES. Hepatol Commun, 2026 Jul 1; 10 (7): DOI:10.1097/HC9.0000000000000990
      PMID: PMC13286549

    Featured News & Stories

    A stylized illustration of a human liver surrounded by several molecular structures labeled "DT-109" on a light yellow background. The liver is depicted in a reddish-brown color. The molecular structures include chemical bonds and letters, indicating a compound related to DT-109.
    Health Lab

    Drug candidate treats severe fatty liver disease by protecting the gut in animal models

    Researchers discovered that a potential drug developed at Michigan Medicine, DT-109, treats severe fatty liver disease by improving gut health.
    liver image with two yellow spots floating artistically
    Health Lab

    Managing cirrhosis pain without drugs

    Michigan Medicine hepatologists are preparing a year-long study looking at the techniques cirrhosis patients can use at home to relieve chronic pain without medication.
    man presenting at conference with glasses dark room screen
    Health Lab

    Lactulose and tai chi show promise preventing falls for cirrhosis patients

    Lactulose and tai chi can prevent falls in patients with cirrhosis, according to results from the LiveSMART Trial run by Michigan Medicine.
    liver
    Department News

    CME Event - 28th Annual Liver Disease Wrap-Up

    Join us for the 28th Annual Liver Disease Wrap-Up, taking place on Saturday, December 6, 2025, from 8:00am - 12:15 pm at the Detroit Marriott Livonia, Livonia, MI.
    Elliot Tapper
    Department News

    Internal Medicine Faculty Spotlight − Dr. Elliot Tapper

    Elliott Tapper, MD, FASSLD is an Associate Professor of Internal Medicine and Academic Chief of Hepatology in the Division of Gastroenterology and Hepatology.
    meditating person hands up on knees in jeans and camel sweatshirt on brown tan rug with plant in background and white wall
    Health Lab

    Can meditation and stretching relieve cramping caused by cirrhosis?

    People suffering from cirrhosis may find some symptom relief from two accessible activities: stretching and meditation. A study from the University of Michigan compared the two therapies as a means to relieve nocturnal muscle cramps and found both effective.