Professor of Internal Medicine
Program Director of Fellowship
Transplant Hepatology
[email protected]
Available to mentor
Robert John Fontana, MD
Professor
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Fellow, GastroenterologyUniversity of Michigan, Ann Arbor, Michigan, 1995
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Chief Medical ResidentSt. Joseph Hospital, Chicago, Illinois, 1992
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Residency, Internal MedicineNorthwestern University, Chicago, Illinois, 1991
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B.S. ChemistryWayne State University, Detroit, Michigan, 1984
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Humphries C, Addison M, Aithal G, Boyd J, Briody L, Campbell JDM, Candela ME, Clarke E, Coulson J, Downing-James N, Fontana RJ, Geddes A, Grahamslaw J, Grant A, Heye A, Hutchinson JA, Jones A, Mitchell F, Moore J, Riddell A, Rodriguez A, Thomas A, Tucker G, Walker K, Weir CJ, Woods R, Zahra S, Forbes SJ, Dear JW. BMJ Open, 2024 Dec 9; 14 (12): e089417Journal ArticleMacrophage Therapy for Acute Liver Injury (MAIL): a study protocol for a phase 1 randomised, open-label, dose-escalation study to evaluate safety, tolerability and activity of allogeneic alternatively activated macrophages in patients with paracetamol-induced acute liver injury in the UK.
DOI:10.1136/bmjopen-2024-089417 PMID: 39653576 -
Miller MJ, Fontana RJ. Liver Transpl, 2024 Dec 1; 30 (12): 1209 - 1211.Journal ArticleAcute liver failure: Do we have a consensus regarding management?
DOI:10.1097/LVT.0000000000000464 PMID: 39172016 -
Fontana RJ, Choi E-YK, Kaganove J, Dodson A. Clin Gastroenterol Hepatol, 2024 Dec; 22 (12): 2538 - 2539.Journal ArticleFirst Report of Tirzepatide Hepatotoxicity with Jaundice.
DOI:10.1016/j.cgh.2024.06.025 PMID: 38964597 -
Fettiplace A, Marcinak J, Merz M, Zhang H-T, Kikuchi L, Regev A, Palmer M, Rockey D, Fontana R, Hayashi PH, Tillmann HL, Di Bisceglie AM, Lewis JH. Aliment Pharmacol Ther, 2024 Nov; 60 (10): 1293 - 1307.Journal ArticleReview article: Recommendations for detection, assessment and management of suspected drug-induced liver injury during clinical trials in oncology patients.
DOI:10.1111/apt.18271 PMID: 39300766 -
Dong V, Durkalski V, Lee WM, Karvellas CJ, and the United States Acute Liver Failure Study Group . Hepatol Commun, 2024 Nov 1; 8 (11):Journal ArticleOutcomes of patients with acute liver failure not listed for liver transplantation: A cohort analysis.
DOI:10.1097/HC9.0000000000000575 PMID: 39470433 -
Conlon C, Li Y-J, Ahmad J, Barnhart H, Fontana RJ, Ghabril M, Hayashi PH, Kleiner DE, Lee WM, Navarro V, Odin JA, Phillips EJ, Stolz A, Vuppalanchi R, Halegoua-DeMarzio D, Drug‐Induced Liver Injury Network (DILIN) . Aliment Pharmacol Ther, 2024 Sep; 60 (6): 787 - 795.Journal ArticleClinical characteristics and HLA associations of azithromycin-induced liver injury.
DOI:10.1111/apt.18160 PMID: 38988034 -
Fontana RJ, Li Y-J, Chen V, Kleiner D, Stolz A, Odin J, Vuppalanchi R, Gu J, Dara L, Barnhart H, Drug-Induced Liver Injury Network . Hepatol Commun, 2024 Sep 1; 8 (9):Journal ArticleGenetic variants associated with immune-mediated liver injury from checkpoint inhibitors.
DOI:10.1097/HC9.0000000000000518 PMID: 39185906 -
Fontana RJ, Li YJ, Vuppalanchi R, Kleiner DE, Gu J, Shroff H, Van Wagner LB, Watkins PB, US DILIN study group . Am J Gastroenterol, 2024 Aug 1; 119 (8): 1496 - 1505.Journal ArticleERAP-1 and ERAP-2 Variants in Liver Injury After COVID-19 mRNA Vaccination: A US Multicenter Study.
DOI:10.14309/ajg.0000000000002702 PMID: 38314748
Department News
Join us for the 27th Annual Liver Disease Wrap-Up conference taking place on Saturday, December 7, 2024
Health Lab
Glucagon-like peptide-1, or GLP-1, receptor agonists, that aid in weight loss, are now being investigated for their ability to help other patients, including those with liver disease. However, a research letter discusses the first known case of hepatitis and jaundice in a patient taking these drugs.
Health Lab
Millions of Americans consume supplements that contain potentially hepatoxic botanical ingredients, according to a study from University of Michigan researchers.
