Srijan Sen
Frances and Kenneth Eisenberg Professor of Depression and Neurosciences
Center Director
University of Michigan Depression Center
Professor of Psychiatry and Research Professor
Michigan Neuroscience Institute
Medical School
[email protected]

Available to mentor

Srijan Sen
Center Director
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    About

    Srijan Sen is the Frances and Kenneth Eisenberg Professor of Depression and Neurosciences and Director of the Eisenberg Family Depression Center at the University of Michigan. He received his M.D. and Ph.D. from the University of Michigan, completed a psychiatry residency at Yale University and returned to Michigan as faculty in 2009. The Intern Health Study is a longitudinal cohort study that assesses stress and mood in training physicians, enrolling over 25,000 participants from 100+ institutions. The project has produced high-impact findings across a wide range of interdisciplinary academic topics including genomics, mobile technology, economics, gender and racial disparities, survey methodology and medical education policy. Work from the study has been published in JAMA, BMJ, New England Journal of Medicine and other leading journals covered in the New York Times, Washington Post, Time Magazine and other media outlets. Dr. Sen is a member of the National Academy of Medicine Collaborative on Clinician Well-Being.

    Center Memberships
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Global REACH
    • Center Member
      Precision Health Initiative
    • Center Member
      Eisenberg Family Depression Center
    • Center Member
      Institute for Healthcare Policy and Innovation
    • Center Member
      Taubman Institute
    • Center Member
      MM-PKUHSC Joint Institute
    Recent Publications See All Publications
    • Journal Article
      Seasonal timing and interindividual differences in shiftwork adaptation.
      Kim R, Fang Y, Lee M, Kim DW, Tang Z, Sen S, Forger DB. NPJ Digit Med, 2025 May 28; 8 (1): 300 DOI:10.1038/s41746-025-01678-z
      PMID: PMC12119876
    • Journal Article
      CareQOL Mobile App: A Low-Burden, Mobile App–Based Intervention for Care Partners of People with Traumatic Brain Injury
      Carlozzi N, Troost J, Sander A, Choi S, Wu Z, Miner J, Lombard W, Graves C, Sen S. Archives of Physical Medicine and Rehabilitation, 2025 Apr 2; 106 (4): e130 DOI:10.1016/j.apmr.2025.01.337
    • Journal Article
      Improving Outcomes for Care Partners of Individuals With Traumatic Brain Injury: Results for a mHealth Randomized Control Trial of the CareQOL App.
      Carlozzi NE, Troost JP, Sen S, Choi SW, Wu Z, Miner JA, Lombard WL, Graves C, Sander AM. Arch Phys Med Rehabil, 2025 Apr; 106 (4): 548 - 561. DOI:10.1016/j.apmr.2024.12.022
      PMID: PMC11968231
    • Preprint
      Depression Risk and Work Hours in Training Physicians Before and During the COVID-19 Pandemic.
      Cleary JL, Pereira-Lima K, Ma X, Chen L, Burmeister M, Meeks LM, Zhao Z, Ye J, Fang Y, Wu Z, Frank E, Zhang R, Zeng S, Zhao Q, Mata DA, Bohnert A, Li W, Sen S. 2025 Mar 17; DOI:10.1101/2025.03.09.25323517
      PMID: 40166545
    • Preprint
      Feasibility and acceptability of collecting passive phone usage and sensor data via Apple SensorKit
      Funk C, Zhao Z, Horwitz AG, Fang Y, Pereira-Lima K, Kheterpal V, Sen S, Frank E. 2025 Feb 9; medRxiv, DOI:10.1101/2025.02.06.25321806
    • Journal Article
      Burnout, Depression, and Diminished Well-Being among Physicians. Reply.
      Guille C, Sen S. N Engl J Med, 2025 Jan 16; 392 (3): 312 DOI:10.1056/NEJMc2415470
      PMID: 39813662
    • Journal Article
      Epigenome-wide association study of perceived discrimination in the Multi-Ethnic Study of Atherosclerosis (MESA).
      Zhao W, Lin L, Kelly KM, Opsasnick LA, Needham BL, Liu Y, Sen S, Smith JA. Epigenetics, 2025 Dec; 20 (1): 2445447 DOI:10.1080/15592294.2024.2445447
      PMID: PMC12118157
    • Journal Article
      Female Physician Suicide Compared to the General Population.
      Frank E, Sen S, Guille C. JAMA Psychiatry, 2025 Feb 26; DOI:10.1001/jamapsychiatry.2024.4786
      PMID: 40009396
    Featured News & Stories Kenneth Eisenberg and the late Frances Eisenberg
    News Release
    $40 million gift supports Michigan Medicine’s new specialty care facility in Troy and mental health research
    A $40 million gift to Michigan Medicine from the Eisenberg Foundation will be honored with the naming of a center for specialty care that will be built in Troy, and will support depression prevention research.
    doctor with head and neck in hands sitting down seeming depressed or stressed
    Health Lab
    More research is needed to support physicians' mental health, experts say
    A pair of researchers who have studied physician mental health and stress call for more efforts to supports to prevent burnout and support wellbeing.
    Dart flying toward target precision medicine
    News Release
    From ‘trial and error’ to targeted precision: $17.9M grant accelerates U-M mental health research
    A new major grant aims to bring the same precision to mental health care for depression, anxiety and other psychiatric conditions that already exists for cancer and heart disease.