Mohamad Hakam Tiba

Mohamad H. Tiba
Research Associate Professor
Emergency Medicine
Medical School
[email protected]
Available to mentor
Mohamad Hakam Tiba
Mohamad H. Tiba
Research Associate Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
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  • About

    I am a Research Associate Professor in the Department of Emergency Medicine at the University of Michigan and a member of the Max Harry Weil Institute of Critical Care Research and Innovation. My research interests include the development of non-invasive monitoring techniques and devices, innovative resuscitative fluids and hemostatic strategies, and the testing of high-fidelity and clinically faithful preclinical models of critical care disease. I currently serve as the director of the Pre-Clinical Critical Care Laboratory (PC3L) at the Weil Institute. The PC3L provides a platform that brings together clinicians, engineers, and basic and clinical investigators to develop high-fidelity preclinical models of critical illness and injury. The PC3L impact lies in establishing the appropriate models to meet these collaborators’ research needs, especially for those with limited resources. Throughout my career, I have served and continue to serve either as a PI or Co-I on several federally and institutionally funded clinical and preclinical research projects. I also serve as a mentor for many undergraduate and graduate students and as a member of several institutional committees such as the IACUC and the Faculty Senate Research Advisory Committee (RAC).

    Links

    • twitter
    • linkedin
    • https://www.researchgate.net/profile/Mohamad_Tiba
    • https://scholar.google.com/citations?user=W250bF4AAAAJ&hl=en
    • Emergency Medicine
    • Max Harry Weil Institute for Critical Care Research and Innovation

    Qualifications

    • Clinical Research Design and Statistical Analysis
      University of Michigan, School of Public Health, Ann Arbor, United States
      2013 - 2015
      Other
    • MS
      University of Michigan, School of Public Health, Ann Arbor, United States
      2013 - 2015
    • MD
      Damascus University, Faculty of Medicine, Damascus, Syrian Arab Republic
      1985 - 1992

    Center Memberships

    • Center Member
      Weil Institute for Critical Care Research

    Research Overview

    Development of pre-clinical models to study critical care illness and injury
    Development of non-invasive technologies to evaluate intravenous volume status in critically ill patients using bioimpedance
    Development of non-invasive technologies to evaluate cerebrovascular autoregulation using ocular bioimpedance
    Development of non-invasive spectroscopic technologies to monitor tissue oxygenation using Resonance Raman Spectroscopy (RRS)
    Development of resuscitation Fluids, hemoglobin, and non-hemoglobin oxygen carriers
    Development of closed-loop feedback CPR devices
    Development of hemorrhage control materials and devices

    Recent Publications

    See All Publications
    • Journal Article
      In sepsis, circulating bacterial DNA correlates with disease severity and is filtered by the lungs.
      Drohan CM, Falkowski NR, Hough TA, Branton WR, Luth JE, Ranjan P, Thau MR, Tiba MH, Stringer KA, Dickson RP. Am J Respir Crit Care Med, 2026 May 13; DOI:10.1093/ajrccm/aamag233
      PMID: 42127977
    • Journal Article
      A103-05 Angiopoietin 2 Inhibition Preserves Hemodynamics in a Swine Model of Sepsis
      Riedmann KJ, Flott T, Tiba MH, Dickson RP, Tetreault J, Liu L, Majumdar A, Singer BH, Stringer KA. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.6173 DOI:10.1093/ajrccm/aamag162.6173
    • Journal Article
      C54-03 Sepsis Precipitates Dynamic Changes in Distinct Monocyte States: Insights From Serial Single-cell Profiling in Pigs
      Resnick JM, Ranjan P, Flott T, Tiba MH, Dickson RP, Stringer KA, Denstaedt SJ. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.5185 DOI:10.1093/ajrccm/aamag162.5185
    • Presentation
      Modulation of Coronary Perfusion Pressure During CPR in Porcine Cardiac Arrest Models
      Tiba M. 2026 May 7;
    • Journal Article
      Pathogen characteristics are key determinants of distinct host response phenotypes of sepsis.
      Chanderraj R, Bartek B, Stringer KA, Tiba MH, Sjoding MW, He Y, Nuppnau M, Bongers KS, Adame MD, Lou SS, Kerschberger VE, Churpek MM, Calfee CS, Tripathi S, Foster DM, Kellum JA, Dickson RP, Sinha P. J Clin Invest, 2026 Mar 16; 136 (6): DOI:10.1172/JCI197346
      PMID: PMC12987626
    • Proceeding / Abstract / Poster
      Abstract Sat203: Rapid UCH-L1 and GFAP Brain Injury Biomarker Detection in Out-of-Hospital Cardiac Arrest: A Swine Model and Prehospital Feasibility Study
      Moll K, Sharpe Z, Harding L, Gomez C, Duckett Z, Greer N, Tiba M, Gherasim C, Korley F, Rees P, Price J, Hsu C. Circulation, 2025 Nov 6; 152 (Suppl_3): asat203 - asat203. DOI:10.1161/circ.152.suppl_3.sat203
    • Proceeding / Abstract / Poster
      Abstract Sat204: Prediction of Common Carotid Flow using Pressure Values in a Swine Model of CPR
      Sharpe Z, Neumar R, Tiba M. Circulation, 2025 Nov 5; 152 (Suppl_3): asat204 - asat204. DOI:10.1161/circ.152.suppl_3.sat204
    • Journal Article
      Assessment of Cerebral Autoregulation Using Ultrasound-Based Intra- and Extracranial Blood Flow Indices in a Swine Model of Brain Injury.
      Tiba MH, Sharpe ZJ, Greer NL, Davis AN, Dennis CA, Picton P, Rajajee V, Ward KR, Rubin JM, Fowlkes JB. J Neurotrauma, 2025 Sep 3; DOI:10.1177/08977151251372544
      PMID: 40899350

    Featured News & Stories

    Dr. Joseph Wider prepares cells for the microscope
    Department News

    Supercharged science: New high-tech microscopes fuel brain injury research in the Emergency Medicine Department

    Thanks to a $1.2 million Department of Defense grant, scientists in the Department of Emergency Medicine can now study cells too fragile to image previously — pushing brain injury research forward with two advanced microscopes and a state-of-the-art brain monitor.
    Photo of a hand holding a magnifying glass over a checklist.
    Research News

    Director of Weil Institute Preclinical Critical Care Lab to serve as U-M Medical School Research Scout

    Dr. Hakam Tiba joins a select team of scientists from the University of Michigan tasked with seeking out and funding innovative research across the Medical School.