Mohamad Hakam Tiba
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About
I am a Research Associate Professor in the Department of Emergency Medicine at the University of Michigan and a member of the Max Harry Weil Institute of Critical Care Research and Innovation. My research interests include the development of non-invasive monitoring techniques and devices, innovative resuscitative fluids and hemostatic strategies, and the testing of high-fidelity and clinically faithful preclinical models of critical care disease. I currently serve as the director of the Pre-Clinical Critical Care Laboratory (PC3L) at the Weil Institute. The PC3L provides a platform that brings together clinicians, engineers, and basic and clinical investigators to develop high-fidelity preclinical models of critical illness and injury. The PC3L impact lies in establishing the appropriate models to meet these collaborators’ research needs, especially for those with limited resources. Throughout my career, I have served and continue to serve either as a PI or Co-I on several federally and institutionally funded clinical and preclinical research projects. I also serve as a mentor for many undergraduate and graduate students and as a member of several institutional committees such as the IACUC and the Faculty Senate Research Advisory Committee (RAC).
Links
twitter linkedin https://www.researchgate.net/profile/Mohamad_Tiba https://scholar.google.com/citations?user=W250bF4AAAAJ&hl=en Emergency Medicine Max Harry Weil Institute for Critical Care Research and Innovation
Qualifications
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Clinical Research Design and Statistical AnalysisUniversity of Michigan, School of Public Health, Ann Arbor, United States
2013 - 2015
Other
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MSUniversity of Michigan, School of Public Health, Ann Arbor, United States
2013 - 2015
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MDDamascus University, Faculty of Medicine, Damascus, Syrian Arab Republic
1985 - 1992
Center Memberships
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Center MemberWeil Institute for Critical Care Research
Research Overview
Development of pre-clinical models to study critical care illness and injury
Development of non-invasive technologies to evaluate intravenous volume status in critically ill patients using bioimpedance
Development of non-invasive technologies to evaluate cerebrovascular autoregulation using ocular bioimpedance
Development of non-invasive spectroscopic technologies to monitor tissue oxygenation using Resonance Raman Spectroscopy (RRS)
Development of resuscitation Fluids, hemoglobin, and non-hemoglobin oxygen carriers
Development of closed-loop feedback CPR devices
Development of hemorrhage control materials and devices
Recent Publications
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Drohan CM, Falkowski NR, Hough TA, Branton WR, Luth JE, Ranjan P, Thau MR, Tiba MH, Stringer KA, Dickson RP. Am J Respir Crit Care Med, 2026 May 13;Journal ArticleIn sepsis, circulating bacterial DNA correlates with disease severity and is filtered by the lungs.
DOI:10.1093/ajrccm/aamag233 PMID: 42127977 -
Riedmann KJ, Flott T, Tiba MH, Dickson RP, Tetreault J, Liu L, Majumdar A, Singer BH, Stringer KA. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.6173Journal ArticleA103-05 Angiopoietin 2 Inhibition Preserves Hemodynamics in a Swine Model of Sepsis
DOI:10.1093/ajrccm/aamag162.6173 -
Resnick JM, Ranjan P, Flott T, Tiba MH, Dickson RP, Stringer KA, Denstaedt SJ. American Journal of Respiratory and Critical Care Medicine, 2026 May 20; 212 (Supplement_1): aamag162.5185Journal ArticleC54-03 Sepsis Precipitates Dynamic Changes in Distinct Monocyte States: Insights From Serial Single-cell Profiling in Pigs
DOI:10.1093/ajrccm/aamag162.5185 -
Tiba M. 2026 May 7;PresentationModulation of Coronary Perfusion Pressure During CPR in Porcine Cardiac Arrest Models
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Chanderraj R, Bartek B, Stringer KA, Tiba MH, Sjoding MW, He Y, Nuppnau M, Bongers KS, Adame MD, Lou SS, Kerschberger VE, Churpek MM, Calfee CS, Tripathi S, Foster DM, Kellum JA, Dickson RP, Sinha P. J Clin Invest, 2026 Mar 16; 136 (6):Journal ArticlePathogen characteristics are key determinants of distinct host response phenotypes of sepsis.
DOI:10.1172/JCI197346 PMID: PMC12987626 -
Moll K, Sharpe Z, Harding L, Gomez C, Duckett Z, Greer N, Tiba M, Gherasim C, Korley F, Rees P, Price J, Hsu C. Circulation, 2025 Nov 6; 152 (Suppl_3): asat203 - asat203.Proceeding / Abstract / PosterAbstract Sat203: Rapid UCH-L1 and GFAP Brain Injury Biomarker Detection in Out-of-Hospital Cardiac Arrest: A Swine Model and Prehospital Feasibility Study
DOI:10.1161/circ.152.suppl_3.sat203 -
Sharpe Z, Neumar R, Tiba M. Circulation, 2025 Nov 5; 152 (Suppl_3): asat204 - asat204.Proceeding / Abstract / PosterAbstract Sat204: Prediction of Common Carotid Flow using Pressure Values in a Swine Model of CPR
DOI:10.1161/circ.152.suppl_3.sat204 -
Tiba MH, Sharpe ZJ, Greer NL, Davis AN, Dennis CA, Picton P, Rajajee V, Ward KR, Rubin JM, Fowlkes JB. J Neurotrauma, 2025 Sep 3;Journal ArticleAssessment of Cerebral Autoregulation Using Ultrasound-Based Intra- and Extracranial Blood Flow Indices in a Swine Model of Brain Injury.
DOI:10.1177/08977151251372544 PMID: 40899350
Featured News & Stories
Supercharged science: New high-tech microscopes fuel brain injury research in the Emergency Medicine Department