Melvin G McInnis, MD, FRCPsych
Thomas B and Nancy Upjohn Woodworth Professor of Bipolar Disorder and Depression
Professor of Psychiatry
Professor of Learning Health Sciences
Program Director of Bipolar Psychiatry
Medical School
[email protected]

Available to mentor
Melvin G McInnis, MD, FRCPsych
Professor
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    Center Memberships
    • Center Member
      Center for Computational Medicine and Bioinformatics
    • Center Member
      Eisenberg Family Depression Center
    Recent Publications See All Publications
    • Journal Article
      Predictive evidence for the impact of personality styles on depression and functioning in two bipolar disorder cohorts.
      Ryan KA, Yocum AK, Zhang Y, Han P, Marshall DF, Costa PT, Sperry SH, Suzuki T, McInnis MG, Zöllner S. J Affect Disord, 2025 Jul 1; 380: 746 - 755. DOI:10.1016/j.jad.2025.03.131
      PMID: 40139400
    • Journal Article
      Circadian clock genes and cell survival in bipolar disorder: Insights into lithium responsiveness and molecular mechanisms in patient-derived neural progenitor cells and mouse neurons.
      Mishra HK, Wei H, LeRoux M, Ko D, Rohr K, Nievergelt CM, Maihofer AX, Shilling PD, Alda M, Berrettini WH, Coryell WH, Frye M, Gershon E, McInnis MG, Nurnberger J, Oedegaard KJ, Zandi PP, Kelsoe JR, McCarthy MJ. FEBS J, 2025 Jun; 292 (11): 2806 - 2822. DOI:10.1111/febs.70034
      PMID: 39995020
    • Journal Article
      Integrating Knowledge: The Power of Ontologies in Psychiatric Research and Clinical Informatics.
      McInnis MG, Coleman B, Hurwitz E, Robinson PN, Williams AE, Haendel MA, McMurry JA. Biol Psychiatry, 2025 May 23; DOI:10.1016/j.biopsych.2025.05.014
      PMID: 40414449
    • Proceeding / Abstract / Poster
      91. Novel Methods for Characterizing and Predicting Mood Instability in Bipolar Disorder
      Sperry S, Stromberg A, Yocum A, Tso I, McInnis M. Biological Psychiatry, 2025 Apr 11; 97 (9): s132 DOI:10.1016/j.biopsych.2025.02.328
    • Journal Article
      Response Monitoring Theta-Band Activities across Emotional Contexts in Schizophrenia- and Bipolar-Spectrum Disorders
      Suzuki T, Menkes MW, McInnis MG, Kang J, Niendam TA, Walton MA, Deldin PJ, Tso IF, Taylor SF. Biological Psychiatry Global Open Science, 2025 May 29; 100540 DOI:10.1016/j.bpsgos.2025.100540
    • Journal Article
      Polygenic Scores and Mood Disorder Onsets in the Context of Family History and Early Psychopathology.
      Freeman K, Zwicker A, Fullerton JM, Hafeman DM, van Haren NEM, Merranko J, Goldstein BI, Stapp EK, de la Serna E, Moreno D, Sugranyes G, Mas S, Roberts G, Toma C, Schofield PR, Edenberg HJ, Wilcox HC, McInnis MG, Propper L, Pavlova B, Stewart SA, Denovan-Wright EM, Rouleau GA, Castro-Fornieles J, Hillegers MHJ, Birmaher B, Mitchell PB, Alda M, Nurnberger JI, Uher R. JAMA Netw Open, 2025 Apr 1; 8 (4): e255331 DOI:10.1001/jamanetworkopen.2025.5331
      PMID: PMC12004201
    • Journal Article
      Suicide risk estimation in bipolar disorder using N200 and P300 event-related potentials and machine learning: A pilot study
      Lee C, Gates KM, Chun J, Kontar RA, Kamali M, McInnis MG, Deldin P. Journal of Affective Disorders Reports, 2025 Apr 1; 20: DOI:10.1016/j.jadr.2025.100875
    • Journal Article
      Alcohol and substance use differentially impact suicidal ideation in a longitudinal cohort of bipolar disorder.
      Smith JL, McInnis MG, Sperry SH. Psychiatry Res, 2025 Feb; 344: 116357 DOI:10.1016/j.psychres.2025.116357
      PMID: PMC12063688
    Featured News & Stories
    Research News
    New Research from the Prechter Program: Exposure to SARS-CoV-2, Acute Kidney Injury, and Lithium Toxicity
    Prechter Program Director and Research Program Manager found instances of lithium toxicity among individuals with bipolar disorder who were diagnosed with COVID-19.