Alice Telesnitsky, PhD
Professor
Microbiology and Immunology
1150 W. Medical Center Drive
Ann Arbor, MI 48109
[email protected]

Available to mentor

Alice Telesnitsky, PhD
Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    Alice Telesnitsky earned her BS degree in Genetics at the University of California, Davis in 1979. She earned her PhD in Biochemistry from the University of California, Berkley in 1988. She performed her post-doctorate fellowship at the College of Physicians and Surgeons Laboratory of Dr. Stephen Goff, Columbia University in New York. She joined the faculty at the University of Michigan, Ann Arbor in 1994, and currently resides over a lab studying the functions and dynamics of RNA in the context of retroviral replication, mechanisms of retroviral genetic variation, and the epigenetics of HIV-1 persistence.

    Links
    • Telesnitsky Lab
    Qualifications
    • Postdoctoral Fellow
      College of Physicians and Surgeons, New York, 1994
    • PhD
      University of California, Berkeley, Berkeley, 1988
    • BS
      University of California, Davis, Davis, 1979
    Center Memberships
    • Center Member
      Global REACH
    Research Overview

    * Retroviral genomic RNA structure, dynamics, and molecular recognition
    * Epigenetics of HIV persistence
    * Mechanisms of retroviral genetic variation
    * Reverse transcriptase enzymology and the process of reverse transcription
    * Determinants and roles of host RNAs in retroviral particles

    Recent Publications See All Publications
    • Journal Article
      Role of RNA structural plasticity in modulating HIV-1 genome packaging and translation.
      Yasin S, Lesko SL, Kharytonchyk S, Brown JD, Chaudry I, Geleta SA, Tadzong NF, Zheng MY, Patel HB, Kengni G, Neubert E, Quiambao JMC, Becker G, Ghinger FG, Thapa S, Williams A, Radov MH, Boehlert KX, Hollmann NM, Singh K, Bruce JW, Marchant J, Telesnitsky A, Sherer NM, Summers MF. Proc Natl Acad Sci U S A, 2024 Aug 13; 121 (33): e2407400121 DOI:10.1073/pnas.2407400121
      PMID: 39110735
    • Journal Article
      Transcription start site heterogeneity and its role in RNA fate determination distinguish HIV-1 from other retroviruses and are mediated by core promoter elements.
      Kharytonchyk S, Burnett C, Gc K, Telesnitsky A. J Virol, 2023 Sep 28; 97 (9): e0081823 DOI:10.1128/jvi.00818-23
      PMID: 37681957
    • Preprint
      Transcription start site heterogeneity and its role in RNA fate determination distinguish HIV-1 from other retroviruses and are mediated by core promoter elements.
      Kharytonchyk S, Burnett C, Gc K, Telesnitsky A. 2023 May 22; DOI:10.1101/2023.05.22.541776
      PMID: 37292892
    • Journal Article
      PP 3.5 – 00110 The proviral quasispecies of HIV-1
      Telesnitsky A, Atindaana E, Gopal K, Emery S, Kidd J, Telesnitsky A. Journal of Virus Eradication, 2022 Dec; 8: 100185 DOI:10.1016/j.jve.2022.100185
    • Journal Article
      Bimodal Expression Patterns, and Not Viral Burst Sizes, Predict the Effects of Vpr on HIV-1 Proviral Populations in Jurkat Cells.
      Atindaana E, Kissi-Twum A, Emery S, Burnett C, Pitcher J, Visser M, Kidd JM, Telesnitsky A. mBio, 2022 Apr 26; 13 (2): e0374821 DOI:10.1128/mbio.03748-21
      PMID: 35384697
    • Journal Article
      Stability and conformation of the dimeric HIV-1 genomic RNA 5'UTR.
      Blakemore RJ, Burnett C, Swanson C, Kharytonchyk S, Telesnitsky A, Munro JB. Biophys J, 2021 Nov 2; 120 (21): 4874 - 4890. DOI:10.1016/j.bpj.2021.09.017
      PMID: 34529947
    • Preprint
      Vpr shapes the proviral landscape and polyclonal HIV-1 reactivation patterns in cultured cells
      Atindaana E, Emery S, Burnett C, Pitcher J, Kidd J, Telesnitsky A. 2021 bioRxiv, DOI:10.1101/2021.10.08.463623
    • Journal Article
      5'-Cap sequestration is an essential determinant of HIV-1 genome packaging.
      Ding P, Kharytonchyk S, Kuo N, Cannistraci E, Flores H, Chaudhary R, Sarkar M, Dong X, Telesnitsky A, Summers MF. Proc Natl Acad Sci U S A, 2021 Sep 14; 118 (37): DOI:10.1073/pnas.2112475118
      PMID: 34493679
    Featured News & Stories
    Department News
    M&I ranks # 10 and A.Telesnitsky, PhD., ranks 10th PI in the Blue Ridge Institute for Medical Research
    M&I ranks # 10 and A.Telesnitsky, PhD, ranks 10th PI in the Blue Ridge Institute for Medical Research