Frederick G L Huetwell Research Professor of Rheumatology II
Assistant Professor in Internal Medicine
Internal Medicine/Rheumatology
2800 Plymouth Road, Building 20, Room 1822
Ann Arbor, Michigan 48109
[email protected]
2800 Plymouth Road, Building 20, Room 1822
Ann Arbor, Michigan 48109
Available to mentor
Eliza PS Tsou, PhD
Assistant Professor
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PhDUniversity at Buffalo/ State University of New York, Buffalo, 2008
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BScNational Taiwan University, Taipei City, 2001
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Center MemberSamuel and Jean Frankel Cardiovascular Center
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Ma F, Tsou P-S, Gharaee-Kermani M, Plazyo O, Xing X, Kirma J, Wasikowski R, Hile GA, Harms PW, Jiang Y, Xing E, Nakamura M, Ochocki D, Brodie WD, Pillai S, Maverakis E, Pellegrini M, Modlin RL, Varga J, Tsoi LC, Lafyatis R, Kahlenberg JM, Billi AC, Khanna D, Gudjonsson JE. Nat Commun, 2024 Jan 3; 15 (1): 210Journal ArticleSystems-based identification of the Hippo pathway for promoting fibrotic mesenchymal differentiation in systemic sclerosis.
DOI:10.1038/s41467-023-44645-6 PMID: 38172207 -
van Straalen KR, Ma F, Tsou P-S, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. J Clin Invest, 2024 Feb 1; 134 (3):Journal ArticleSingle-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
DOI:10.1172/JCI169225 PMID: 38051587 -
Shi B, Tsou P-S, Ma F, Mariani MP, Mattichak MN, LeBrasseur NK, Chini EN, Lafyatis R, Khanna D, Whitfield ML, Gudjonsson JE, Varga J. J Invest Dermatol, 2023 Apr; 143 (4): 661 - 664.e5.Journal ArticleSenescent Cells Accumulate in Systemic Sclerosis Skin.
DOI:10.1016/j.jid.2022.09.652 PMID: 36191640 -
Kortam N, Liang W, Shiple C, Huang S, Gedert R, Clair JS, Sarosh C, Foster C, Tsou P-S, Varga J, Knight JS, Khanna D, Ali RA. Arthritis Res Ther, 2024 Jul 25; 26 (1): 139Journal ArticleElevated neutrophil extracellular traps in systemic sclerosis-associated vasculopathy and suppression by a synthetic prostacyclin analog.
DOI:10.1186/s13075-024-03379-6 PMID: 39054558 -
Hile G, Ma F, Tsou P, Gharaee-Kermani M, Zhang L, Victory A, Hurst A, Xu B, Pedersen E, Wasikowski R, Berthier C, Ognenovski V, Nakamura M, Billi A, Gudjonsson JE, Kahlenberg M. Journal of Investigative Dermatology, 2024 Aug; 144 (8): s150Proceeding / Abstract / PosterLB860 Cross-disease comparison of dermatomyositis and SLE identifies non-classical monocytes and JAK-1 signaling as drivers of endothelial cell death in DM skin
DOI:10.1016/j.jid.2024.06.1240 -
Gurrea-Rubio M, Wang Q, Mills EA, Wu Q, Pitt D, Tsou P-S, Fox DA, Mao-Draayer Y. Int J Mol Sci, 2024 Feb 20; 25 (5):Journal ArticleSiponimod Attenuates Neuronal Cell Death Triggered by Neuroinflammation via NFκB and Mitochondrial Pathways.
DOI:10.3390/ijms25052454 PMID: 38473703 -
Gurrea-Rubio M, Wu Q, Amin MA, Tsou P-S, Campbell PL, Amarista CI, Ikari Y, Brodie WD, Mattichak MN, Muraoka S, Randon PM, Lind ME, Ruth JH, Mao-Draayer Y, Ding S, Shen X, Cooney LA, Lin F, Fox DA. Cancer Immunol Immunother, 2024 Jan 27; 73 (2): 34Journal ArticleActivation of cytotoxic lymphocytes through CD6 enhances killing of cancer cells.
DOI:10.1007/s00262-023-03578-1 PMID: 38280067 -
O'Reilly S, Tsou P-S, Varga J. Trends Mol Med, 2024 Jun 17;Journal ArticleSenescence and tissue fibrosis: opportunities for therapeutic targeting.
DOI:10.1016/j.molmed.2024.05.012 PMID: 38890028
Health Lab
Targeting and blocking the sCD13 protein from interacting with the B1R protein can pave the way for new fibrosis and systemic sclerosis treatments.
